IP Library Granted Patent US 12,443,020
Granted Patent B2
US 12,443,020 · App. 18/369,592 · Granted Oct 14, 2025

Visualization devices, systems, and methods for otology and other uses

Inventors: Eugene de Juan (South San Francisco, CA); Signe Erickson (South San Francisco, CA); Vrad Levering (South San Francisco, CA)
Assignee: Spiral Therapeutics, Inc.
G02B21/0012A61B1/018A61B1/227A61B17/29A61B17/320068A61B17/3205A61B17/3423A61B17/3468A61B17/3478A61B18/04A61B18/1485A61B18/20A61F2/958A61F11/20A61F11/202A61M31/00A61M31/002A61M37/0015G02B21/0032G02B21/22A61B2017/00115A61B2017/00787A61B2017/00867A61B2017/32007A61B2018/00327A61B2217/005A61F2002/183A61F2250/0067A61M2037/0023A61M2037/0046A61M2205/04A61M2210/0662A61M2210/0668
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,443,020
App. No.
18/369,592
Granted
Oct 14, 2025
Kind
B2
Abstract

Devices, systems, and methods can be employed to facilitate indirect viewing into cavities such as, but not limited to, the middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. In particular implementations, a surgical microscope is used in conjunction with an inverter lens and a distal lens. In some cases, the distal lens transverses a membrane or septum such as, but not limited to, the tympanic membrane. The distal lens can be an assembly combining two or more lenses, in some embodiments. For example, in some cases wide angle lenses, zoom lenses, lenses of other various shapes and/or prisms can be used in the distal lens.

Claims (22)

1. A medical visualization system for viewing a middle ear region, comprising:

a tympanic membrane lens assembly having an outer diameter of 1 mm to 5 mm and being mountable to a tympanic membrane to facilitate visualization through the tympanic membrane and into a middle ear region, wherein the tympanic membrane lens assembly comprises a widefield lens at a distal-most end of the tympanic membrane lens assembly such that the widefield lens is positioned interiorly to the tympanic membrane when the tympanic membrane lens assembly is mounted to the tympanic membrane, and wherein a proximal-most end of the tympanic membrane lens assembly is configured to transfer an image of the middle ear region captured by the widefield lens and is positioned externally to the tympanic membrane when the tympanic membrane lens assembly is mounted to the tympanic membrane.

2. The system of claim 1 , further comprising a stereoscopic inverter lens assembly positionable external to the tympanic membrane to receive the image of the middle ear region from the proximal-most end of the tympanic membrane lens assembly.

3. The system of claim 2 , wherein the stereoscopic inverter lens assembly is adjustably mounted to a surgical microscope.

4. The system of claim 1 , wherein the proximal-most end of the tympanic membrane lens assembly comprises a prism.

5. The system of claim 4 , wherein the tympanic membrane lens assembly further comprises a zoom or objective lens disposed between the prism and the widefield lens.

6. The system of claim 5 , wherein the tympanic membrane lens assembly defines a waist having a smaller outer diameter than immediately adjacent proximal and distal portions of the tympanic membrane lens assembly.

7. The system of claim 1 , wherein the tympanic membrane lens assembly comprises a radially extending arm or ring to stabilize the tympanic membrane lens assembly relative to the tympanic membrane.

8. The system of claim 1 , wherein the tympanic membrane lens assembly comprises a housing that defines an interior space between the widefield lens and the proximal-most end of the tympanic membrane lens assembly.

9. The system of claim 1 , further comprising a speculum and an external lens assembly mechanically coupled to the speculum, wherein the external lens assembly is positionable external to the tympanic membrane to receive the image of the middle ear region from the proximal-most end of the tympanic membrane lens assembly.

10. The system of claim 9 , wherein the external lens assembly is adjustably mounted to the speculum.

11. A method for indirect viewing into a middle ear region of a patient, the method comprising:

mounting a tympanic membrane lens assembly to a tympanic membrane, wherein the tympanic membrane lens assembly comprises a widefield lens at a distal-most end of the tympanic membrane lens assembly such that the widefield lens is positioned interiorly to the tympanic membrane and a proximal-most end of the tympanic membrane lens is positioned externally to the tympanic membrane, wherein the proximal-most end of the tympanic membrane lens assembly is configured to transfer an image of the middle ear region captured by the widefield lens; and

viewing the image of the middle ear region captured by the widefield lens at the distal-most end of the tympanic membrane lens assembly and transferred from the proximal-most end of the tympanic membrane lens assembly.

12. The method of claim 11 , wherein the image of the middle ear region captured by the widefield lens at the distal-most end of the tympanic membrane lens assembly is transferred from the proximal-most end of the tympanic membrane lens assembly to a stereoscopic inverter lens assembly positioned external to the tympanic membrane.

13. The method of claim 12 , wherein the stereoscopic inverter lens assembly is adjustably mounted to a surgical microscope.

14. The method of claim 11 , wherein said viewing the image comprises viewing the image of the middle ear region view a surgical microscope positioned external to the tympanic membrane.

15. The system claim 14 , wherein said viewing comprises a hands-free operation of the surgical microscope.

16. The method of claim 11 , wherein the proximal-most end of the tympanic membrane lens assembly comprises a prism.

17. The method of claim 16 , wherein the tympanic membrane lens assembly further comprises a zoom or objective lens disposed between the prism and the widefield lens.

18. The method of claim 11 , wherein said mounting the tympanic membrane lens assembly to the tympanic membrane comprises engaging a waist of the tympanic membrane lens assembly with the tympanic membrane, the waist having a smaller outer diameter than immediately adjacent proximal and distal portions of the tympanic membrane lens assembly.

19. The method of claim 11 , wherein said mounting the tympanic membrane lens assembly to the tympanic membrane comprises engaging a radially extending arm or ring of the tympanic membrane lens assembly to the tympanic membrane so as to stabilize the tympanic membrane lens assembly relative to the tympanic membrane.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2023
From: JUAN, EUGENE DE; ERICKSON, SIGNE; LEVERING, VRAD
To: SPIRAL THERAPEUTICS INC.
Reel/Frame 065116/0029 →
Continuity (11)
Continuation 17155580 · Jan 22, 2021
Provisional Application 63082996 · Sep 24, 2020
Provisional Application 63081015 · Sep 21, 2020
Provisional Application 63080510 · Sep 18, 2020
Provisional Application 63078141 · Sep 14, 2020
Provisional Application 63077448 · Sep 11, 2020
Provisional Application 63051568 · Jul 14, 2020
Provisional Application 63040495 · Jun 17, 2020
Provisional Application 63024183 · May 13, 2020
Provisional Application 62965481 · Jan 24, 2020
Related Publication 20240019674A1 · Jan 18, 2024
References Cited (51)
US 4335713A · Komiya · 1982 [cited by applicant]
US 5421818A · Arenberg · 1995 [cited by applicant]
US 6024726A · Hill · 2000 [cited by applicant]
US 6045528A · Arenberg et al. · 2000 [cited by applicant]
US 6120484A · Silverstein · 2000 [cited by applicant]
US 6440102B1 · Arenberg et al. · 2002 [cited by applicant]
US 6648873B2 · Arenberg et al. · 2003 [cited by applicant]
US 7351246B2 · Epley · 2008 [cited by applicant]
US 7704259B2 · Kaplan et al. · 2010 [cited by applicant]
US 8197461B1 · Arenberg et al. · 2012 [cited by applicant]
US 9352084B2 · Decker et al. · 2016 [cited by applicant]
US 9616207B2 · Verhoeven et al. · 2017 [cited by applicant]
US 10098529B2 · Gao et al. · 2018 [cited by applicant]
US 10130514B2 · Imran et al. · 2018 [cited by applicant]
US 10492670B1 · Bendory et al. · 2019 [cited by applicant]
US 11796781B2 · de Juan · 2023 [cited by examiner]
US 20030220536A1 · Hissong · 2003 [cited by applicant]
US 20040133099A1 · Dyer et al. · 2004 [cited by applicant]
US 20040172005A1 · Arenberg et al. · 2004 [cited by applicant]
US 20040263958A1 · Bihr et al. · 2004 [cited by applicant]
US 20110142274A1 · Perkins et al. · 2011 [cited by applicant]
US 20110152621A1 · Magalhaes Mendes et al. · 2011 [cited by applicant]
US 20110224629A1 · Jolly et al. · 2011 [cited by applicant]
US 20120203200A1 · Kenney et al. · 2012 [cited by applicant]
US 20130060131A1 · Oghalai et al. · 2013 [cited by applicant]
US 20130245569A1 · Jolly et al. · 2013 [cited by applicant]
US 20130267783A1 · Davis et al. · 2013 [cited by applicant]
US 20150031941A1 · Perkins et al. · 2015 [cited by applicant]
US 20160346511A1 · Cohen et al. · 2016 [cited by applicant]
US 20170172804A1 · Watanabe et al. · 2017 [cited by applicant]
US 20170239091A1 · Franz · 2017 [cited by examiner]
US 20190015254A1 · Bendory et al. · 2019 [cited by applicant]
US 20190321610A1 · Goldfarb et al. · 2019 [cited by applicant]
US 20200094030A1 · Kim et al. · 2020 [cited by applicant]
CN 1829468A · 2006 [cited by applicant]
CN 102429630A · 2012 [cited by applicant]
DE 3539009 · 1987 [cited by applicant]
GB 2255651 · 1992 [cited by applicant]
JP S55110528 · 1980 [cited by applicant]
JP H05130974 · 1993 [cited by applicant]
WO WO1994010596 · 1994 [cited by applicant]
WO WO2008097317 · 2008 [cited by applicant]
WO WO2019116024 · 2019 [cited by applicant]
WO WO2019152866 · 2019 [cited by applicant]
WO WO2019200259 · 2019 [cited by applicant]
WO WO2020115674 · 2020 [cited by applicant]
Extended European Search Report in European Appln No. 21744103.9, dated Jan. 22, 2024, 8 pages. [cited by applicant]
Ent4Kids.co, “Microscopic Examination & Procedures,” Ent4kids, retrieved on May 8, 2023, retrieved from URL<https://www.ent4kids.co.uk/pagem>, 3 pages. [cited by applicant]
International Preliminary Report on Patentability in International Appln. No. PCT/US2021/014609, mailed on Aug. 4, 2022, 8 pages. [cited by applicant]
PCT International Search Report and Written Opinion in International Appln. No. PCT/US2021/014609, dated Apr. 8, 2021, 10 pages. [cited by applicant]
Zeiss, “Zeiss Surgical Microscopes,” Ent4kids, retrieved on May 8, 2023, retrieved from URL<https://www.zeiss.com/meditec/en/products/surgical-microscopes.html#ent-surgery>, 12 pages. [cited by applicant]