Body fluid component separating device
View Patent ↗A body fluid component separating device according to an embodiment may comprise: a housing; a piston which divides the housing into a first space and a second space and connects the first space and the second space via fluid-connection; and a manipulator which is coupled to the piston to be operable and is configured to maintain a pressure balance between the first space and the second space, adjust movement of the piston between a first location at which the first space has a first volume and a second location at which the first space has a second volume that is different from the first volume, and fix the piston on an arbitrary location between the first location and the second location.
1. A body fluid component separating device comprising:
a housing comprising a container and a lid that define a space sealed against the outside;
a piston configured to divide the sealed space of the housing into a first space and a second space and to fluidly connect the first space and the second space;
a manipulator configured to adjust a movement of the piston between a first location in which the first space has a first volume and a second location in which the first space has a second volume different from the first volume, and configured to fix the piston at an arbitrary location between the first location and the second location, the manipulator being operably coupled to the piston; and
a filter structure configured to fluidly connect the first space and the second space and to filter a fluid flowing from the first space to the second space,
wherein the body fluid component separating device is configured to maintain the pressure balance between the first space and the second space such that when the piston descends, a pressure of the first space increases, and a pressure of the second space decreases regardless of an external force that causes the piston to move downward,
wherein the manipulator comprises:
a shaft having a longitudinal axis;
a male engagement element formed on the shaft;
a female engagement element engaged with the male engagement element and fixedly installed to the piston;
a handle comprising a first engagement member; and
a second engagement member connected to the shaft and engaged with the first engagement member,
wherein when the manipulator is not operated by the male engagement element, the female engagement element, handle, and the second engagement member, the manipulator fixes a position of the piston with respect to the housing, and wherein the lid comprises a piston guide configured to guide a movement of the piston, and
wherein the filter structure comprises:
a filter housing having an inlet port fluidly connected to the first space, a first outlet port fluidly connected to the second space, and a second outlet port fluidly connected to the second space and disposed opposite the first outlet port;
a first filter installed in the first outlet port; and
a second filter installed in the second outlet port.
2. The body fluid component separating device of claim 1 , further comprising:
an indicator configured to fluidly connect the first space and the second space and to indicate a layer including a target material flowing from the first space to the second space.
3. The body fluid component separating device of claim 2 , wherein the indicator comprises:
a tube comprising an inlet port, an outlet port, and a main channel defined between the inlet port and the outlet port; and
an insert disposed inside the tube and on the main channel, and configured to define a sub-channel having a cross section less than a cross section of the main channel together with the tube.
4. The body fluid component separating device of claim 3 , wherein the insert comprises a guide portion to guide a fluid flowing through the main channel to the sub-channel.
5. The body fluid component separating device of claim 1 , wherein
the filter structure comprises a tube that includes a first end portion fluidly connected to the first space, a second end portion fluidly connected to the inlet port of the filter housing, and a longitudinal portion extending between the first end portion and the second end portion, and
the second end portion of the tube protrudes from an inner wall of the filter housing toward an inside of the filter housing.
6. The body fluid component separating device of claim 1 , wherein the piston comprises:
an outer body moving along the housing;
an inner body located inside the outer body;
a partition configured to connect an end portion of the outer body and an end portion of the inner body and configured to partition an interior of the housing into the first space and the second space; and
a fluid passage extending between the outer body and the inner body and from the partition and configured to fluidly connect the first space and the second space.
7. The body fluid component separating device of claim 6 , wherein the partition comprises a groove to receive a target material.