IP Library › Granted Patent US 12,453,842
Granted Patent B2
US 12,453,842 · App. 18/043,873 · Granted Oct 28, 2025

Catheters adapted for agent delivery

Inventors: Thomas Roewer (Sunnyvale, CA); Michael P. Allen (Los Altos, CA)
Assignee: Embolx, Inc.
A61M25/1018A61M25/0023A61M25/09A61M2025/0042
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Quick Facts
Patent No.
US 12,453,842
App. No.
18/043,873
Granted
Oct 28, 2025
Kind
B2
Abstract

Medical delivery devices, such as catheters, and methods of use and manufacture of the medical delivery devices. The medical delivery devices are adapted to facilitate delivery of an agent into a patient. The medical delivery devices may have one or more deformable lumens, each lumen of the one or more deformable lumens has a collapsed configuration and an open configuration. The medical delivery devices may include one or more agent delivery ports, any agent delivery port of the one or more agent delivery ports may be proximal or distal to an expandable device, such as a balloon.

Claims (25)

1. A catheter for delivering an agent into a patient, the catheter comprising:

an outer shaft comprising one or more agent delivery ports;

a guidewire channel within the outer shaft, the guidewire channel defining a guidewire lumen sized and configured to receive a guidewire in the guidewire lumen;

a balloon inflation channel within the outer shaft, the balloon inflation channel defining a balloon inflation lumen in fluid communication with an internal volume of an inflatable balloon; and

an agent delivery lumen defined by an inner surface of the outer shaft, an outer surface of the guidewire channel and an outer surface of the balloon inflation channel,

the agent delivery lumen in communication with the one or more agent delivery ports, and the one or more agent delivery ports proximal to at least a portion of the inflatable balloon, and

wherein a proximal portion of the guidewire channel is deformable between an open guidewire configuration and a collapsed, agent-delivery configuration.

2. The catheter of claim 1 , wherein the proximal portion of the guidewire channel is biased to the collapsed, agent-delivery configuration.

3. The catheter of claim 1 , wherein the proximal portion of the guidewire channel is adapted to deform towards the collapsed, agent-delivery configuration in response to an increase in fluid pressure in the agent delivery lumen.

4. The catheter of claim 1 , wherein the open guidewire configuration is a circular cross-sectional configuration, and the collapsed, agent-delivery configuration is not a circular cross-sectional configuration.

5. The catheter of claim 1 , wherein the guidewire lumen, in a cross-section transverse to a long axis of the catheter and through the proximal portion of the guidewire channel, has an area when the guidewire channel is in the open guidewire configuration that is greater than an area when the guidewire channel is in the collapsed, agent-delivery configuration.

6. The catheter of claim 1 , wherein the agent delivery lumen, in a cross-section transverse to a long axis of the catheter and through the proximal portion of the guidewire channel, has an area when the guidewire channel is in the open guidewire configuration that is less than an area when the guidewire channel is in the collapsed, agent-delivery configuration.

7. The catheter of claim 1 , wherein the agent delivery lumen has a greater volume when the guidewire channel is in the collapsed, agent-delivery configuration than when the guidewire channel is in the open guidewire configuration.

8. The catheter of claim 1 , wherein the guidewire channel is not adapted to collapse in a distal region that extends within the inflatable balloon.

9. The catheter of claim 1 , further comprising a balloon support coupled to the balloon inflation channel, the balloon support comprising one or more balloon inflation ports in fluid communication with the balloon inflation lumen and the internal volume of the inflatable balloon to facilitate inflation of the inflatable balloon.

10. The catheter of claim 9 , wherein the balloon inflation channel has a distal end that is disposed within a first lumen defined by the balloon support, the first lumen in fluid communication with the one or more balloon inflation ports.

11. The catheter of claim 10 , wherein the first lumen has a non-circular cross-sectional configuration.

12. The catheter of claim 10 , wherein the balloon inflation channel has a first cross-sectional configuration in a first portion that is proximal to the inflatable balloon that is circular, and wherein the balloon inflation channel has a second cross-sectional configuration in a second portion within the first lumen that is non-circular.

13. The catheter of claim 1 , further comprising a balloon support that includes a support lumen extending through the balloon support, at least a portion of the guidewire channel is disposed within the support lumen.

14. The catheter of claim 13 , wherein the guidewire channel extends through the support lumen and at least to a distal end of the support lumen.

15. The catheter of claim 1 , wherein the outer shaft is secured to a proximal end of a balloon support, and wherein the balloon is secured to the inflatable balloon support.

16. The catheter of claim 15 , wherein the balloon support is adapted to prevent elongation of the ballon support to thereby prevent elongation of the inflatable balloon.

17. The catheter of claim 16 , wherein the inflatable balloon support comprises one or more strengthening elements to prevent the elongation of the inflatable balloon.

18. The catheter of claim 1 , further comprising a balloon support, wherein the guidewire channel is secured to the balloon support thereby preventing a distal portion of the guidewire channel from collapsing within the balloon support.

19. The catheter of claim 1 , wherein the proximal portion of the guidewire channel is biased to the open guidewire configuration.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 30, 2023
From: ROEWER, THOMAS; ALLEN, MICHAEL P.
To: EMBOLX, INC.
Reel/Frame 064757/0978 →
Continuity (2)
Provisional Application 63202989 · Jul 2, 2021
Related Publication 20230226328A1 · Jul 20, 2023
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