IP Library › Granted Patent US 12,453,868
Granted Patent B2
US 12,453,868 · App. 18/208,425 · Granted Oct 28, 2025

Patient volume segmentation apparatus and method

Inventors: Xinhui Yang (Oberrohrdorf, CH); Armel Rosselet (Baden, CH); Daniel von Büren (Sierentz, FR)
Assignee: Varian Medical Systems Particle Therapy GmbH & Co. KG
A61N5/1039G06T5/50G06T7/0012G06T7/10G06T2207/10072G06T2207/10116G06T2211/404
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,453,868
App. No.
18/208,425
Granted
Oct 28, 2025
Kind
B2
Abstract

By one approach, a control circuit accesses planning computed tomography image information for a particular patient. The control circuit also accesses two-dimensional digital subtraction angiography image information for the particular patient. The control circuit then fuses the planning computed tomography image information with the two-dimensional digital subtraction angiography image information to provide fused image information of the patient target volume.

Claims (35)

1 . A method to facilitate segmenting a patient target volume in support of radiation treatment planning, the method comprising:

by a control circuit:

accessing planning computed tomography image information for a particular patient;

accessing two-dimensional digital subtraction angiography image information for the particular patient;

fusing the planning computed tomography image information with the two-dimensional digital subtraction angiography image information to provide fused image information of the patient target volume.

2 . The method of claim 1 wherein the patient target volume comprises, at least in part, an arteriovenous malformation.

3 . The method of claim 1 wherein the planning computed tomography image information comprises, at least in part, segmented three-dimensional contours from corresponding computed tomography image information and wherein fusing the planning computed tomography image information with the two-dimensional digital subtraction angiography image information comprises, at least in part, projecting the segmented three-dimensional contours into two-dimensional contours on the two-dimensional digital subtraction angiography image information.

4 . The method of claim 1 further comprising:

generating the two-dimensional digital subtraction angiography image information as a function of at least two x-ray images.

5 . The method of claim 4 wherein the at least two x-ray images include two images that are at least substantially orthogonal to one another.

6 . The method of claim 1 wherein the two-dimensional digital subtraction angiography image information for the particular patient includes at least one closed two-dimensional contour surrounding an image of the patient target volume on each of at least two two-dimensional digital subtraction angiography images.

7 . The method of claim 1 wherein fusing the planning computed tomography image information with the two-dimensional digital subtraction angiography image information comprises, at least in part, and for each image pair of x-ray and planning computed tomography images, effecting a registration therebetween.

8 . The method of claim 1 further comprising:

simultaneously presenting on an interactive user display:

at least two digital subtraction angiography images that each include pre-delineated two-dimensional guide structures that correspond to the patient target volume and at least one pipeline projection;

at least three three-dimensional planning computed tomography images.

9 . The method of claim 8 , wherein the at least three three-dimensional planning computed tomography images include an axial image, a sagittal image, and a coronal image.

10 . The method of claim 8 , wherein the at least three three-dimensional planning computed tomography images each include a three-dimensional guide box that is reconstructed from two-dimensional guide contours from at least two of the digital subtraction angiography images.

11 . An apparatus to facilitate segmenting a patient target volume in support of radiation treatment planning, the apparatus comprising:

a control circuit configured to:

access planning computed tomography image information for a particular patient;

access two-dimensional digital subtraction angiography image information for the particular patient;

fuse the planning computed tomography image information with the two-dimensional digital subtraction angiography image information to provide fused image information of the patient target volume.

12 . The apparatus of claim 11 wherein the patient target volume comprises, at least in part, an arteriovenous malformation.

13 . The apparatus of claim 11 wherein the planning computed tomography image information comprises, at least in part, segmented three-dimensional contours from corresponding computed tomography image information and wherein the control circuit is configured to fuse the planning computed tomography image information with the two-dimensional digital subtraction angiography image information by, at least in part, projecting the segmented three-dimensional contours into two-dimensional contours on the two-dimensional digital subtraction angiography image information.

14 . The apparatus of claim 11 wherein the control circuit is further configured to: generate the two-dimensional digital subtraction angiography image information as a function of at least two x-ray images.

15 . The apparatus of claim 14 wherein the at least two x-ray images include two images that are at least substantially orthogonal to one another.

16 . The apparatus of claim 11 wherein the two-dimensional digital subtraction angiography image information for the particular patient includes at least one closed two-dimensional contour surrounding an image of the patient target volume on each of at least two two-dimensional digital subtraction angiography images.

17 . The apparatus of claim 11 wherein the control circuit is configured to fuse the planning computed tomography image information with the two-dimensional digital subtraction angiography image information by, at least in part, and for each image pair of x-ray and planning computed tomography images, effecting a registration therebetween.

18 . The apparatus of claim 11 wherein the control circuit is further configured to:

simultaneously present on an interactive user display:

at least two digital subtraction angiography images that each include pre-delineated two-dimensional guide structures that correspond to the patient target volume and at least one pipeline projection;

at least three three-dimensional planning computed tomography images.

19 . The apparatus of claim 18 , wherein the at least three three-dimensional planning computed tomography images include an axial image, a sagittal image, and a coronal image.

20 . The apparatus of claim 18 , wherein the at least three three-dimensional planning computed tomography images each include a three-dimensional guide box that is reconstructed from two-dimensional guide contours from at least two of the digital subtraction angiography images.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2024
From: YANG, XINHUI; ROSSELET, ARMEL; VON BUREN, DANIEL
To: VARIAN MEDICAL SYSTEMS IMAGING LABORATORY GMBH
Reel/Frame 067534/0763 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2024
From: VARIAN MEDICAL SYSTEMS IMAGING LABORATORY GMBH
To: VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH & CO. KG
Reel/Frame 067534/0776 →
Continuity (1)
Related Publication 20240408409A1 · Dec 12, 2024
References Cited (15)
US 7995824B2 · Yim · 2011 [cited by applicant]
US 11410317B2 · Paul · 2022 [cited by applicant]
US 20080109013A1 · Fu · 2008 [cited by examiner]
US 20090005668A1 · West · 2009 [cited by applicant]
US 20210370097A1 · Thomas · 2021 [cited by examiner]
US 20220230310A1 · Xie · 2022 [cited by applicant]
US 20220409929A1 · Rusanen · 2022 [cited by examiner]
US 20230094681A1 · Lambin · 2023 [cited by examiner]
US 20230095485A1 · Czeizler · 2023 [cited by examiner]
US 20240001139A1 · Kuusela · 2024 [cited by examiner]
CN 112509077A · 2021 [cited by applicant]
EP 3746980B1 · 2022 [cited by applicant]
Coste, Eric et al.; 3D reconstruction of the encapsulating contour of arteriovenous malformations for radiosurgery using digital subtraction angiography; Int J Radiat Oncol Biol Phys May 1, 2001;50(1):247-55. [cited by applicant]
Extended European Search Report from related European Patent Application No. 24180434.3 dated Nov. 18, 2024; 8 pages. [cited by applicant]
Liao, Rui et al.; A Review of Recent Advances in Registration Techniques Applied to Minimally Invasive Therapy; IEEE Transactions on Multimedia, vol. 15, No. 5, Aug. 31, 2013, pp. 983-1000; DOI: 10.1109/TMM.2013.2244869. [cited by applicant]