IP Library Granted Patent US 12,458,049
Granted Patent B2
US 12,458,049 · App. 17/807,798 · Granted Nov 4, 2025

Steviol glycoside solubility enhancers

Inventors: Dan S. Gaspard (Victoria, MN); Adam T. Zarth (St. Louis Park, MN)
Assignee: CARGILL, INCORPORATED
A23L27/36A23F3/34A23L2/56A23L2/60A23L2/68A23L5/40A23L27/30A23L27/39A23L27/88A61K31/192A61K31/235A61K36/28B01D15/361C07H15/256C07K1/16C07K1/18A23V2002/00A23V2200/15A23V2250/258A61K2236/31A61K2236/39
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Quick Facts
Patent No.
US 12,458,049
App. No.
17/807,798
Granted
Nov 4, 2025
Kind
B2
Abstract

A solubilized steviol glycoside composition including one or more steviol glycosides and one or more steviol glycoside solubility enhancers can be used as a sweetener composition to sweeten other compositions (sweetenable compositions) such as foods, beverages, medicines, oral hygiene compositions, pharmaceuticals, nutraceuticals, and the like.

Claims (35)

1 . An aqueous steviol glycoside solution comprising:

a) greater than 0.3% by weight of a total steviol glycoside composition comprising rebaudioside M, rebaudioside D, or combinations thereof; and

b) a steviol glycoside solubility enhancer composition in an amount such that the aqueous solution comprises a 1:0.3 to 1:3 ratio by weight of steviol glycoside to solubility enhancer composition, the steviol glycoside solubility enhancer composition comprising

i) one or more monocaffeoylquinic acids or salts thereof; and

ii) at least 20% by weight of one or more dicaffeoylquinic acids or salts thereof;

wherein the steviol glycoside remains in solution for at least 7 days at about 25° C.

2 . The aqueous steviol glycoside solution of claim 1 wherein the total steviol glycoside composition comprises about 1% or less by weight of rebaudioside A.

3 . The aqueous steviol glycoside solution of claim 1 , wherein the total steviol glycoside composition comprises 90 wt % or greater of the combination of rebaudioside D and rebaudioside M.

4 . The aqueous steviol glycoside solution of claim 1 comprising less 10% by weight of a C1-C4 alcohol.

5 . The aqueous steviol glycoside solution of claim 4 which is free of the C1-C4 alcohol.

6 . The aqueous steviol glycoside solution of claim 1 , wherein the solution is substantially free of one or more of malonate, malonic acid, oxalate, oxalic acid, succinate, succinic acid, malate, malic acid, pyruvate, pyruvic acid, fumarate, fumaric acid, tartrate, tartaric acid, sorbate, sorbic acid, acetate, acetic acid, ammonia, ammonium, kaempferol, myricetin, fisetin, galangin, isorhamnetin, pachypodol, rhamnazin, pyranoflavonols, furanoflavonols, luteolin, apigenin, tangeritin, or chlorophyll.

7 . The aqueous steviol glycoside solution of claim 1 , wherein the solution comprises greater than 0.5% by weight steviol glycosides.

8 . The aqueous steviol glycoside solution of claim 1 , wherein the solution comprises greater than 3% by weight steviol glycosides.

9 . The aqueous steviol glycoside solution of claim 1 having a pH of 2 to 4.

10 . A beverage composition comprising the aqueous steviol glycoside solution of claim 1 and one or more of phosphoric acid, citric acid, sodium citrate, and carbonated water.

11 . The aqueous steviol glycoside solution of claim 1 , wherein the aqueous solution comprises a 1:1 to 1:3 ratio by weight of steviol glycoside to solubility enhancer composition.

12 . The aqueous steviol glycoside solution of claim 1 , wherein the solution comprises greater than 1.0% by weight steviol glycosides.

13 . A sweetener comprising:

a) a steviol glycoside composition comprising rebaudioside D, rebaudioside M, or a combination thereof;

b) a steviol glycoside solubility enhancer composition comprising (i) one or more monocaffeoylquinic acids or salts thereof; and (ii) at least 20% by weight of one or more dicaffeoylquinic acids or salts thereof,

wherein the sweetener is soluble in water without alcohol at a temperature of about 25° C. at a total steviol glycoside concentration of greater than 0.3% by weight.

14 . An aqueous steviol glycoside solution comprising:

a) greater than 0.3% by weight of a total steviol glycoside composition comprising rebaudioside D, rebaudioside M, or a combination thereof; and

b) a steviol glycoside solubility enhancer composition comprising

i) one or more monocaffeoylquinic acids or salts thereof; and

ii) at least 20% by weight of one or more dicaffeoylquinic acids or salts thereof;

wherein the solution comprises a 1:1 to 1:3 ratio by weight of steviol glycoside to solubility enhancer compound; and

wherein the steviol glycoside remains in solution for at least 7 days at about 25° C.

15 . The aqueous steviol glycoside solution of claim 14 , wherein the steviol glycoside composition additionally comprises rebaudioside A.

16 . The aqueous steviol glycoside solution of claim 14 , wherein the steviol glycoside composition comprises 90 wt % or greater of the combination of rebaudioside D and rebaudioside M.

17 . The aqueous steviol glycoside solution of claim 14 , wherein the solution is free of C1-C4 alcohol.

18 . The aqueous steviol glycoside solution of claim 14 , wherein the solution comprises greater than 0.5% by weight steviol glycosides.

19 . The aqueous steviol glycoside solution of claim 14 , wherein the solution comprises greater than 3% by weight steviol glycosides.

20 . The aqueous steviol glycoside solution of claim 14 , wherein the solution has a pH of 2 to 4.

21 . The aqueous steviol glycoside solution of claim 14 , wherein the solution comprises greater than 1.0% by weight steviol glycosides.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2023
From: GASPARD, DAN S.; ZARTH, ADAM T.
To: CARGILL, INCORPORATED
Reel/Frame 063855/0301 →
Continuity (5)
Continuation 16373206 · Apr 2, 2019
Continuation PCTUS2018054691 · Oct 5, 2018
Provisional Application 62676722 · May 25, 2018
Provisional Application 62569279 · Oct 6, 2017
Related Publication 20220323528A1 · Oct 13, 2022
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