Method and system for monitoring brain function and intracranial pressure
View Patent ↗Embodiments of the present systems and methods may provide improved, automated monitoring of brain function. In embodiments, a multimodal, multi-sensor monitoring device may provide to monitoring of the full spectrum of brain function. In an embodiment, a system for monitoring brain function of a subject may include an apparatus for mounting a plurality of stimulus and response sensors on a head of the subject, including a cognizance stimuli-sensor suite, a physiologic sensor suite, and advance monitoring devices such as a transcranial Doppler puck, an electroencephalograph monitor, and an optic nerve sheath parameter sensor.
1 . A portable system for monitoring brain function of a subject, comprising:
an apparatus configured for mounting a plurality of stimulus devices and a plurality of response sensors on a head of the subject, the plurality of stimulus devices including at least one cognizance stimulus device selected from a speaker to provide auditory stimuli to the subject and fall an internal display to provide visual stimuli to the subject, and the plurality of response sensors including at least one cognizance sensor selected from a microphone to record sounds made by the subject, a camera to record eye position and movement of the subject, and a touch/motion sensor to receive input from the subject;
a processor and memory for executing and storing program instructions to provide stimuli to the subject using the plurality of stimulus devices, to receive responses of the subject recorded by the plurality of response sensors, and to process the received responses to generate response information; and
an external display mounted to the apparatus and configured to display the generated response information.
2 . The system of claim 1 , further comprising communications circuitry to transmit the received responses and the generated response information and to receive information relating to stimuli to be provided to the subject.
3 . The system of claim 1 , wherein the plurality of response sensors further includes at least one physiological sensor selected from a vibration sensor, a heart rate monitor, a blood oxygen saturation sensor, a temperature sensor, a head position sensor, and a vibration microphone.
4 . The system of claim 1 , further comprising a vibration sensor configured to remove background vibration artifacts from signals received at the plurality of response sensors.
5 . The system of claim 1 , further comprising at least one of a transcranial Doppler device, an electroencephalograph monitor device, and an optic nerve sheath diameter measurement device.
6 . The system of claim 1 , further comprising an optic nerve sheath diameter measurement device that comprises a two-dimensional array of ultrasonic transducers to scan across the optic nerve sheath, wherein
the processor is configured for receiving and processing data obtained from the two-dimensional array of ultrasonic transducers, calculating volumes of segments of an optical nerve sheath of a subject, and producing a three-dimensional image of the optical nerve sheath on the external a graphical display in communication with the processor.
7 . The system of claim 6 , wherein the processer stores an algorithm for calculating the volume of segments of the optic nerve sheath.
8 . The system of claim 6 , wherein the two-dimensional array of ultrasonic transducers comprises lights for aligning the ultrasonic transducers with the optic nerve sheath.
9 . The system of claim 1 , wherein the apparatus is a pair of goggles.
10 . A portable telemedicine system for monitoring brain function of a subject, comprising:
a wearable platform comprising a plurality of stimulus devices, a plurality of response sensors, and an external display screen each mounted to the wearable platform, wherein the plurality of stimulus devices comprise a speaker to provide auditory stimuli to the subject and an internal display to provide visual stimuli to the subject, and the plurality of response sensors comprise a microphone to record sounds made by the subject, a camera to record eye position and movement of the subject, and a touch/motion sensor to receive input from the subject, and wherein the external display screen is configured to display information received at the plurality of response sensors; and
a processor and memory for executing and storing program instructions to provide stimuli to the subject using the plurality of stimulus devices, to receive responses of the subject recorded by the plurality of response sensors, and to process the received responses to generate response information.
11 . The system of claim 10 , further comprising communications circuitry to transmit the received responses and the generated response information and to receive information relating to stimuli to be provided to the subject.
12 . The system of claim 10 , wherein the plurality of response sensors further includes at least one physiological sensor selected from a vibration sensor, a heart rate monitor, a blood oxygen saturation sensor, a temperature sensor, a head position sensor, and a vibration microphone.
13 . The system of claim 10 , further comprising a vibration sensor configured to remove background vibration artifacts from signals received at the plurality of response sensors.
14 . The system of claim 10 , wherein the plurality of response sensors are used to monitor the subject's level of consciousness.
15 . The system of claim 10 , further comprising at least one of a transcranial Doppler device, an electroencephalograph monitor device, and an optic nerve sheath diameter measurement device.
16 . The system of claim 15 , wherein the transcranial Doppler device, the electroencephalograph monitor device, and the optic nerve sheath diameter measurement device are only activated after the subject has been determined to be unconscious.
17 . A method for automatic monitoring of brain function in a subject in need thereof, utilizing the system of claim 10 , comprising,
placing the wearable platform onto the head of the subject in need of monitoring,
providing stimuli to the subject through one of the plurality of stimulus devices,
recording the subject's response or lack of response to the stimuli, and
displaying the subject's response on the external display screen.
18 . The method of claim 17 , wherein the subject is in a mass casualty environment, is being transported, or is undergoing surgery.