IP Library › Granted Patent US 12,465,612
Granted Patent B2
US 12,465,612 · App. 18/095,493 · Granted Nov 11, 2025

Method of using extract of Dendrobii Caulis and method of protecting eye

Inventors: Yi-Yueh Wang (Taipei, TW); Yun-Lian Lin (Taipei, TW); Wei-Hsiang Hsu (Taipei, TW)
Assignee: AXR PHARMA INC.
A61K31/55A61K36/8984A61P27/02
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Quick Facts
Patent No.
US 12,465,612
App. No.
18/095,493
Granted
Nov 11, 2025
Kind
B2
Abstract

The present invention provides an extract of Dendrobii Caulis with eye care effect, wherein the extract of Dendrobii Caulis has an active ingredient including a picrotoxane-type sesquiterpene. The present invention further provides a pharmaceutical composition with eye care and a use of an extract of Dendrobii Caulis for preparing a pharmaceutical composition with eye care effect.

Claims (2)

1 . A method of protecting an eye, comprising administering an effective amount of an extract of Dendrobii Caulis, wherein the extract of Dendrobii Caulis has an active ingredient comprising 2β, 3β, 11, 12-tetrahydroxypicrotoxan-3(15)-olide 11-O-β-D-glucopyranoside.

2 . The method according to claim 1 , wherein the active ingredient has a weight percentage of 12-20%.

Assignments (2)
CHANGE OF NAME Recorded Jan 15, 2024
From: AMX PHARMA INC.
To: AXR PHARMA INC.
Reel/Frame 066305/0995 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2023
From: WANG, YI-YUEH; LIN, YUN-LIAN; HSU, WEI-HSIANG
To: AMX PHARMA INC.
Reel/Frame 062334/0671 →
Continuity (2)
Division 16796893 · Feb 20, 2020
Related Publication 20230142504A1 · May 11, 2023
References Cited (2)
US 20190365668A1 · Chao · 2019 [cited by examiner]
Meng, C.W., et al., Picrotoxane sesquiterpenoids from the stems of Dendrobium nobile and their absolute configurations and angiogenesis effect, Fitoterapia 121 (2017) 206-211 (Year: 2017). [cited by examiner]