Granted Patent
B2
US 12,486,287 · App. 17/426,882 · Granted Dec 2, 2025
Solid forms of a promoter of spinogenesis
Assignee:
Spinogenix, Inc.
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Abstract
Provided herein are crystalline forms of 2-(2-(2-(2-(4-(benzo[d]thiazol-2-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethan-1-ol (Compound I): Also provided are processes of manufacture and methods of using the crystalline forms.
Claims (4)
1 . Crystalline 2-(2-(2-(2-(4-(benzo[d]thiazol-2-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethan-1-ol (Compound I Form I) characterized by an X-ray powder diffractogram comprising the following peaks (° 2θ±0.2° 2θ): 4.6, 20.8, and 23.7 as determined on a diffractometer using Cu-Kα radiation at a wavelength of 1.5406 Å.
2 . Compound I Form I according to claim 1 , wherein the diffractogram further comprises peaks (° 2θ±0.2° 2θ) at 9.2, 16.3, about 18.6, and 19.6.
3 . Compound I Form I according to claim 1 , characterized by a differential scanning calorimetry (DSC) curve that comprises an endotherm at 70° C. ±2° C.
4 . A pharmaceutical composition comprising the crystalline form of claim 1 and one or more pharmaceutically acceptable carriers.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 3, 2022
From: SARRAF, STELLA T.; VADAS, ELIZABETH BÜCHLER
To: SPINOGENIX, INC.
Reel/Frame 058879/0219 →
Continuity (2)
Provisional Application
62799644
· Jan 31, 2019
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