IP Library › Granted Patent US 12,494,291
Granted Patent B2
US 12,494,291 · App. 17/101,378 · Granted Dec 9, 2025

Systems and methods for reporting blood flow characteristics

Inventors: Charles A. Taylor (Atherton, CA); Gregory R. Hart (Hayden Lake, ID)
Assignee: Heartflow, Inc.
G16H50/50A61B5/02007A61B5/026A61B5/743A61B5/7475G16H10/60G16H30/20G16H15/00
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Quick Facts
Patent No.
US 12,494,291
App. No.
17/101,378
Filed
Nov 23, 2020
Granted
Dec 9, 2025
Kind
B2
Examiner
TRAN, THO Q
Art Unit
3791
USPC
600/504
Abstract

Embodiments include a system for displays cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart and create a model representing at least a portion of the patient's heart based on the patient-specific data. The computer system may determine at least one value of the blood flow characteristic within the patient's heart based on the model. The computer system may also display a report comprising a representation of at least one artery corresponding to at least a portion the model, and display one or more indicators of the value of the blood flow characteristic on a corresponding portion of the at least one artery.

Claims (56)

1 . A system for displaying cardiovascular information of a patient, the system comprising:

at least one data storage device storing instructions for displaying cardiovascular information of a patient; and

at least one processor configured to execute the instructions to perform operations comprising:

receive patient-specific data regarding a geometry of the patient's heart;

create a model representing at least a portion of the patient's heart based on the patient-specific data;

determine a presence of at least one occlusion in at least one artery of the patient's heart based on the patient-specific data, wherein the at least one artery corresponds to at least a portion of the model;

determine at least one value of a patient-specific blood flow characteristic for the at least one artery based on the model;

generate a report comprising a representation of the at least one artery based on at least one of the model or the patient-specific data and a summary portion including a listing of the at least one artery adjacent to a graph of one or more markers of the at least one value of the patient-specific blood flow characteristic for each of the at least one artery, wherein the summary portion prioritizes and lists a presence of at least one occlusion within the summary portion first and prior to the patient-specific blood flow characteristic;

upon determining the presence of the at least one occlusion, automatically truncating the representation of the at least one artery containing the at least one occlusion at a predetermined distance to the at least one occlusion; and

display on the report one or more indicators of the at least one occlusion on a corresponding portion of the representation of the at least one artery.

2 . The system of claim 1 , the operations further comprising:

generate a plurality of notifications to a user based on the patient-specific data, wherein at least one of the plurality of notifications comprises an occlusion notification that notifies the user of the at least one occlusion; and

display the occlusion notification on the report before remaining notifications in the plurality of notifications.

3 . The system of claim 1 , wherein an indicator of an occlusion is displayed on the report if the at least one artery, at a location proximate to the occlusion, has a lumen diameter above a predetermined threshold.

4 . The system of claim 1 , the operations further comprising:

determine at least one value of a fractional flow reserve within the patient's heart based on the model; and

display an indicator, in the report, of the at least one value of the fractional flow reserve proximate to an arterial intersection upstream from an occlusion.

5 . The system of claim 1 , wherein the representation comprises a first artery display and a second artery display, and wherein an indicator of an occlusion visually indicates a point on the first artery display and a corresponding point on the second artery display.

6 . The system of claim 1 , the operations further comprising:

determine a percentage of myocardium of the patient's heart placed at risk by the at least one occlusion; and

display at least one indicator of the portion of the myocardium placed at risk by the at least one occlusion.

7 . A computer-implemented method for displaying cardiovascular information of a patient, comprising:

receiving patient-specific data regarding a geometry of the patient's heart;

creating a model representing at least a portion of the patient's heart based on the patient-specific data;

determining a presence of at least one occlusion in at least one artery of the patient's heart based on the patient-specific data, wherein the at least one artery corresponds to at least a portion of the model;

determining at least one value of a patient-specific blood flow characteristic for the at least one artery based on the model;

generating a report comprising a representation of the at least one artery based on at least one of the model or the patient-specific data and a summary portion including a listing of the at least one artery adjacent to a graph of one or more markers of the at least one value of the patient-specific blood flow characteristic for each of the at least one artery, wherein the summary portion prioritizes and lists a presence of at least one occlusion within the summary portion first and prior to the patient-specific blood flow characteristic;

truncating the representation of the at least one artery containing the at least one occlusion at a predetermined distance to the at least one occlusion; and

displaying on the report one or more indicators of the at least one occlusion on a corresponding portion of the representation of the at least one artery.

8 . The method of claim 7 , further comprising:

generating a plurality of notifications to a user based on the patient-specific data, wherein at least one of the plurality of notifications comprises an occlusion notification that notifies the user of the at least one occlusion; and

displaying the occlusion notification on the report before remaining notifications in the plurality of notifications.

9 . The method of claim 7 , wherein an indicator of an occlusion is displayed on the report if the at least one artery, at a location proximate to the occlusion, has a lumen diameter above a predetermined threshold.

10 . The method of claim 7 , further comprising:

determining at least one value of a fractional flow reserve within the patient's heart based on the model; and

displaying an indicator, in the report, of the at least one value of the fractional flow reserve proximate to an arterial intersection upstream from an occlusion.

11 . The method of claim 7 , wherein the representation comprises a first artery display and a second artery display, and wherein an indicator of an occlusion visually indicates a point on the first artery display and a corresponding point on the second artery display.

12 . The method of claim 7 , further comprising:

determining a percentage of myocardium of the patient's heart placed at risk by the at least one occlusion; and

displaying at least one indicator of the portion of the myocardium placed at risk by the at least one occlusion.

13 . A non-transitory computer-readable medium storing instructions that, when executed by a processor, cause the processor to perform a method for displaying cardiovascular information of a patient, the method including:

receiving patient-specific data regarding a geometry of the patient's heart;

creating a model representing at least a portion of the patient's heart based on the patient-specific data;

determining a presence of at least one occlusion in at least one artery of the patient's heart based on the patient-specific data, wherein the at least one artery corresponds to at least a portion of the model;

determining at least one value of a patient-specific blood flow characteristic for the at least one artery based on the model;

generating a report comprising a representation of the at least one artery based on at least one of the model or the patient-specific data and a summary portion including a listing of the at least one artery adjacent to a graph of one or more markers of the at least one value of the patient-specific blood flow characteristic for each of the at least one artery, wherein the summary portion prioritizes and lists a presence of at least one occlusion within the summary portion first and prior to the patient-specific blood flow characteristic;

upon determining the presence of the at least one occlusion, automatically truncating the representation of the at least one artery containing the at least one occlusion at a predetermined distance to the at least one occlusion; and

displaying on the report one or more indicators of the at least one occlusion on a corresponding portion of the representation of the at least one artery.

14 . The computer-readable medium of claim 13 , wherein the method further comprises:

generating a plurality of notifications to a user based on the patient-specific data, wherein at least one of the plurality of notifications comprises an occlusion notification that notifies the user of the at least one occlusion; and

displaying the occlusion notification on the report before remaining notifications in the plurality of notifications.

15 . The computer-readable medium of claim 13 , wherein an indicator of an occlusion is displayed on the report if the at least one artery, at a location proximate to the occlusion, has a lumen diameter above a predetermined threshold.

16 . The computer-readable medium of claim 13 , wherein the method further comprises:

determining at least one value of a fractional flow reserve within the patient's heart based on the model; and

displaying an indicator, in the report, of the at least one value of the fractional flow reserve proximate to an arterial intersection upstream from an occlusion.

17 . The computer-readable medium of claim 13 , wherein the representation comprises a first artery display and a second artery display, and wherein an indicator of an occlusion visually indicates a point on the first artery display and a corresponding point on the second artery display.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Sep 11, 2025
From: HAYFIN SERVICES LLP
To: HEARTFLOW, INC.
Reel/Frame 072876/0775 →
RELEASE OF SECURITY INTEREST Recorded Jun 21, 2024
From: HAYFIN SERVICES LLP
To: HEARTFLOW, INC.
Reel/Frame 067801/0032 →
SECURITY INTEREST Recorded Jun 18, 2024
From: HEARTFLOW, INC.
To: HAYFIN SERVICES LLP
Reel/Frame 067775/0966 →
SECURITY INTEREST Recorded Jan 20, 2021
From: HEARTFLOW, INC.
To: HAYFIN SERVICES LLP
Reel/Frame 055037/0890 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 22, 2020
From: TAYLOR, CHARLES A.; HART, GREGORY R.
To: HEARTFLOW, INC.
Reel/Frame 054717/0955 →
Continuity (4)
Continuation 15253335 · Aug 31, 2016
Continuation 14480870 · Sep 9, 2014
Provisional Application 62005272 · May 30, 2014
Related Publication 20210074435A1 · Mar 11, 2021
References Cited (47)
US 6616611B1 · Moehring · 2003 [cited by applicant]
US 8315812B2 · Taylor · 2012 [cited by applicant]
US 8548778B1 · Hart et al. · 2013 [cited by applicant]
US 8824752B1 · Fonte et al. · 2014 [cited by applicant]
US 20020045830A1 · Powers et al. · 2002 [cited by applicant]
US 20040002660A1 · Mielekamp · 2004 [cited by examiner]
US 20040243006A1 · Nakata et al. · 2004 [cited by applicant]
US 20050203427A1 · Judy · 2005 [cited by applicant]
US 20060004279A1 · Ikeda · 2006 [cited by examiner]
US 20070238999A1 · Specht · 2007 [cited by applicant]
US 20080118131A1 · Skinner et al. · 2008 [cited by applicant]
US 20090043208A1 · Hergum et al. · 2009 [cited by applicant]
US 20100086189A1 · Wang et al. · 2010 [cited by applicant]
US 20100130866A1 · Main et al. · 2010 [cited by applicant]
US 20100157041A1 · Klaiman et al. · 2010 [cited by applicant]
US 20110066042A1 · Pandia et al. · 2011 [cited by applicant]
US 20110074813A1 · Masumoto · 2011 [cited by applicant]
US 20110319762A1 · Lerman et al. · 2011 [cited by applicant]
US 20120041739A1 · Taylor · 2012 [cited by applicant]
US 20120101552A1 · Lazarewicz et al. · 2012 [cited by applicant]
US 20130030295A1 · Huennekens et al. · 2013 [cited by applicant]
US 20130150734A1 · Orr et al. · 2013 [cited by applicant]
US 20130216110A1 · Zheng · 2013 [cited by examiner]
US 20130231554A1 · Jung · 2013 [cited by applicant]
US 20130261420A1 · Kucherov · 2013 [cited by examiner]
US 20130303888A1 · Deladi et al. · 2013 [cited by applicant]
US 20140039276A1 · Hattangadi et al. · 2014 [cited by applicant]
US 20140088414A1 · Mittal et al. · 2014 [cited by applicant]
US 20140100442A1 · Begin · 2014 [cited by examiner]
US 20140249784A1 · Sankaran · 2014 [cited by applicant]
US 20150157259A1 · Bradu · 2015 [cited by applicant]
US 20150245776A1 · Hirohata · 2015 [cited by applicant]
US 20150250395A1 · Igarashi · 2015 [cited by applicant]
US 20150324962A1 · Itu · 2015 [cited by applicant]
US 20150359601A1 · Sauer et al. · 2015 [cited by applicant]
US 20160228071A1 · Wang · 2016 [cited by applicant]
EP 2302545 · 2011 [cited by applicant]
EP 2484285 · 2012 [cited by applicant]
JP 2009537207A · 2009 [cited by examiner]
JP 2013010005 · 2013 [cited by applicant]
KR 20100069668A · 2010 [cited by examiner]
WO 2006076409 · 2006 [cited by applicant]
WO WO2014059241A1 · 2014 [cited by examiner]
WO 2014067233 · 2015 [cited by applicant]
Notice of Reasons for Rejection received in related JP application No. 2016-567087, dated Oct. 10, 2018. [cited by applicant]
International Search Report and Written Opinion mailed on Sep. 30, 2015, in corresponding International PCT Application No. PCT/US15/33030, filed on May 30, 2015 (10 pages). [cited by applicant]
Vranckx et al. “Coronary Pressure-Derived Fractional Flow Reserve Measurements, Circulation; Cardiovascular Interventions” 2012;5:312-317, originally published Apr. 17, 2012. [cited by applicant]
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