Phase analyzer, sample analyzer, and analysis method
A phase analyzer includes a data acquisition unit that acquires a plurality of pieces of spectrum imaging data in which positions on a sample are associated with spectra which are based on signals from the sample; a first acquisition unit that acquires a first representative spectrum group for each piece of spectrum imaging data by performing multivariate analysis on each of the plurality of pieces of spectrum imaging data; a second acquisition unit that acquires a second representative spectrum group by performing multivariate analysis on the plurality of first representative spectrum groups acquired by the first acquisition unit; and a phase analysis unit that performs phase analysis on each of the plurality of pieces of spectrum imaging data by using the second representative spectrum group.
1 . A phase analyzer comprising:
a data acquisition unit that acquires a plurality of pieces of spectrum imaging data in which positions on a sample are associated with spectra which are based on signals from the sample;
a first acquisition unit that acquires a first representative spectrum group for each piece of spectrum imaging data by performing multivariate analysis on each of the plurality of pieces of spectrum imaging data by extracting representative spectra from a plurality of X-ray spectra included in each of the plurality of pieces of spectrum imaging data, thereby acquiring a plurality of first representative spectrum groups comprising a collection of spectra representing the plurality of X-ray spectra included in each of the plurality of pieces of spectrum imaging data;
a second acquisition unit that acquires a second representative spectrum group by performing multivariate analysis on the plurality of first representative spectrum groups acquired by the first acquisition unit by extracting representative spectra from each of the plurality of first representative spectrum groups to acquire the second representative spectrum group, which is an overall representative spectrum group comprising a plurality of representative spectra representing all of the plurality of pieces of spectrum imaging data;
a classification unit that classifies the plurality of representative spectra included in the second representative spectrum group acquired by the second acquisition unit and creates clusters; and
a phase analysis unit that performs phase analysis on each of the plurality of pieces of spectrum imaging data by using the second representative spectrum group by determining a similarity between an X-ray spectrum of each pixel of the plurality of pieces of spectrum imaging data and each representative spectrum included in the second representative spectrum group and determining one of the clusters to which each pixel belongs.
2 . The phase analyzer according to claim 1 , wherein
the phase analysis unit creates a phase map for each of the pieces of spectrum imaging data by classifying a spectrum of each pixel by using the second representative spectrum group, and
the phase analysis unit creates a combined phase map by combining the phase maps created respectively for the pieces of spectrum imaging data.
3 . The phase analyzer according to claim 1 , wherein
the first acquisition unit divides the plurality of pieces of spectrum imaging data into a plurality of groups, and
the first acquisition unit acquires the first representative spectrum group for each of the groups by performing multivariate analysis on each of the groups.
4 . The phase analyzer according to claim 1 , wherein
the second acquisition unit classifies the spectrum of each pixel in each of the plurality of pieces of spectrum imaging data using the first representative spectrum groups, and generates spectrum groups by integrating or averaging spectra belonging to each type, and
the second acquisition unit acquires the second representative spectrum group by performing multivariate analysis on the plurality of spectrum groups.
5 . A sample analyzer comprising the phase analyzer according to claim 1 .
6 . An analysis method comprising:
acquiring a plurality of pieces of spectrum imaging data in which positions on a sample are associated with spectra which are based on signals from the sample;
acquiring a first representative spectrum group for each piece of spectrum imaging data by performing multivariate analysis on each of the plurality of pieces of spectrum imaging data by extracting representative spectra from a plurality of X-ray spectra included in each of the plurality of pieces of spectrum imaging data, thereby acquiring a plurality of first representative spectrum groups comprising a collection of spectra representing the plurality of X-ray spectra included in each of the plurality of pieces of spectrum imaging data;
acquiring a second representative spectrum group by performing multivariate analysis on the acquired plurality of first representative spectrum groups by extracting representative spectra from each of the plurality of first representative spectrum groups to acquire the second representative spectrum group, which is an overall representative spectrum group comprising a plurality of representative spectra representing all of the plurality of pieces of spectrum imaging data;
classifying the plurality of representative spectra included in the second representative spectrum group acquired by the second acquisition unit and creates clusters; and
performing phase analysis on each of the plurality of pieces of spectrum imaging data by using the second representative spectrum group by determining a similarity between an X-ray spectrum of each pixel of the plurality of pieces of spectrum imaging data and each representative spectrum included in the second representative spectrum group and determining one of the clusters to which each pixel belongs.