IP Library › Granted Patent US 12,514,870
Granted Patent B2
US 12,514,870 · App. 18/519,251 · Granted Jan 6, 2026

Leave-on oral care compositions

Inventors: Ross Strand (Singapore, SG); Yang Su (Beijing, CN); Yunming Shi (Beijing, CN); Xiaoxiao Li (Beijing, CN); Guannan Wang (Beijing, CN)
Assignee: The Procter & Gamble Company
A61K31/728A61C19/063A61G11/00A61K8/60A61K8/673A61K8/676A61K8/678A61K8/735A61K8/8147A61K9/0053A61K31/197A61K31/355A61K31/375A61K31/7016A61K47/32A61K2800/30A61K2800/87
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Quick Facts
Patent No.
US 12,514,870
App. No.
18/519,251
Granted
Jan 6, 2026
Kind
B2
Abstract

Leave-on oral care compositions comprising a hyaluronic acid and a gum-strengthening polyol are provided for promoting Gum Health of a user.

Claims (28)

1 . An oral care composition comprising:

a) from about 0.1% to about 10%, by weight of the composition, of a polyacrylic acid;

b) from about 0.01% to about 10%, by weight of the composition, of a hyaluronic acid or a salt thereof; and

c) from about 0.5% to about 20%, by weight of the composition, of a gum-strengthening polyol;

wherein the oral care composition is a spreadable leave-on gel composition with a Viscosity Consistency Coefficient of about 50 Pa-s to 250 Pa-s and is substantially free of abrasive.

2 . The oral care composition of claim 1 , wherein the gum-strengthening polyol is selected from the group consisting of trehalose, rafiose, stachyose, verbascose, isomalt, maltitol, lactitol, maltotriitol, maltotetraitol, polyglycitol, and combinations thereof.

3 . The oral care composition of claim 2 , wherein the gum-strengthening polyol is trehalose or isomalt.

4 . The oral care composition of claim 1 , further comprising from about 0.2% to about 5%, by weight of the composition, of the polyacrylic acid.

5 . The oral care composition of claim 1 , wherein the hyaluronic acid has a weight average molecular weight of from about 900,000 Daltons to about 5,000,000 Daltons, and wherein the hyaluronic acid is present in the amount of from about 0.1% to about 5.0%, by weight of the composition.

6 . The oral care composition of claim 1 , further comprising from about 0.1% to about 10%, by weight of the composition, of an additional polymer selected from the group consisting of xanthan gum, carrageenan, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, polyvinyl pyrrolidine, co-polymers of maleic anhydride with methyl vinyl ether having a weight average molecular weight of about 30,000 Daltons to about 1,000,000 Daltons, and combinations thereof.

7 . The oral care composition of claim 6 , wherein the additional polymer is present in the amount of from about 0.5% to about 6%, by weight of the composition.

8 . The oral care composition of claim 1 , wherein a total water content is from about 40% to about 80%, by weight of the composition.

9 . The oral care composition of claim 1 , further comprising a humectant selected from the group consisting of glycerin, sorbitol, xylitol, erythritol, butylene glycol, polyethylene glycol, propylene glycol, and combinations thereof.

10 . The oral care composition of claim 9 , wherein the humectant is present in the amount of from about 1% to about 50%, by weight of the composition.

11 . The oral care composition of claim 1 , wherein the oral care composition is substantially free of ethanol.

12 . The oral care composition of claim 1 , further comprising a vitamin selected from the group consisting of Vitamin C, Vitamin E, Vitamin B5, and combinations thereof.

13 . The oral care composition of claim 1 , wherein the composition comprises about 0.5% to about 18%, by weight of the composition, of the gum-strengthening polyol.

14 . The oral care composition of claim 1 , wherein the composition comprises from about 0.1% to about 5.0%, by weight of the composition, of the hyaluronic acid.

15 . A method of improving Gum Health of a subject, the method comprising:

applying the oral care composition of claim 1 onto intraoral tissue of the subject; and

leaving the oral care composition on the intraoral tissue for a duration of time of from about 1 minute to about 1000 minutes.

16 . The method of claim 15 , wherein the oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

17 . A method of improving Gum Health of a subject, the method comprising the steps of:

(a) brushing teeth of the subject with an antibacterial toothpaste; and

(b) subsequently, applying the oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue for a duration of time of at least about 2 minutes.

18 . The method of claim 17 , wherein the oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

19 . A kit comprising a toothpaste and the oral care composition of claim 1 .

20 . A kit comprising the oral care composition of claim 1 and a delivery carrier.

Priority Claims (2)
WO PCT/CN2019/091325 · Jun 14, 2019 · international
WO PCT/CN2020/095578 · Jun 11, 2020 · international
Continuity (2)
Continuation 16899919 · Jun 12, 2020
Related Publication 20240082295A1 · Mar 14, 2024
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