Detection of nicotine, cannabinoids and drugs of abuse on vaping device surfaces and vaping liquid formulations
Provided herein is a portable test device, mass manufacture method and method of use for identification of at least one target drug of abuse. The portable detection kit can include a catalytic reagent, a solid support carrier, and an absorbent material. The colorimetric reagent and the catalytic reagent can be are affixed to the solid support carrier to form a reaction zone thereon. The colorimetric reagent and the catalytic reagent are configured to undergo chemical reaction with at least one target drug of abuse to produce a visible color change. The at least one target drug of abuse is selected from the group consisting of nicotine, cannabinoids, amphetamines, opioids, or cocaine. A target drug of abuse can be on vaping device surfaces and/or within vaping liquid formulations.
1 . A portable detection kit for identifying at least one target drug of abuse comprising:
a dry reaction zone that was printed onto the solid support and affixed thereto comprising a mixture of a 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and a catalytic reagent selected from the group consisting of a mineral acid, an oxalic acid, a citric acid, sodium bisulfate and any combination thereof; and
a separate absorbent material;
wherein the 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and the catalytic reagent are configured to undergo chemical reaction with at least one target drug of abuse to produce a visible color change; and
wherein the at least one target drug of abuse is selected from the group consisting of nicotine, cannabinoids, amphetamines, opioids, or cocaine; and
wherein the catalytic reagent increases the rate of appearance of the visible color change resulting from chemical reaction between the 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and the at least one target drug of abuse; and
wherein a ratio of the 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and the catalytic reagent in the mixture is about 1:1 by weight to about 1:5 by weight.
2 . A portable detection kit as in claim 1 , wherein the 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and catalytic reagent are configured to undergo chemical reaction with the at least one target drug of abuse in the form of liquids, gels or solid powders that are pure or admixed with a cutting agent.
3 . The portable detection kit of claim 1 , wherein the catalytic reagent is in a solid form and comprises at least one of oxalic acid, citric acid, or sodium bisulfate.
4 . The portable detection kit of claim 1 , wherein the separate absorbent material is a cotton swab, or wipe formed from natural or synthetic fibers.
5 . The portable detection kit of claim 4 , wherein the separate absorbent material is packaged in a container.
6 . The portable detection kit of claim 5 , wherein the container is in the form of a form fill seal pouch 12 micron thick, aluminum 7 micron thick, polyethylene 50 micron thick, or a heat seal pouch.
7 . The portable detection kit of claim 1 , wherein the solid support is a paper card, a paper sheet, synthetic paper, Whatman filter paper, polypropylene, or polyethylene synthetic paper.
8 . A portable detection kit for identifying at least one target drug of abuse comprising:
a dry reaction zone that was printed onto the solid support and affixed thereto comprising a mixture of a 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and a catalytic reagent selected from the group consisting of a mineral acid, an oxalic acid, a citric acid, sodium bisulfate and any combination thereof; and
a separate absorbent material;
wherein the 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and the catalytic reagent are configured to undergo chemical reaction with at least one target drug of abuse to produce a visible color change; and
wherein the at least one target drug of abuse is selected from the group consisting of nicotine, cannabinoids, amphetamines, opioids, or cocaine; and
wherein the catalytic reagent increases the rate of appearance of the visible color change resulting from chemical reaction between the 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and the at least one target drug of abuse; and
wherein the 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and the catalytic reagent are combined in a ratio of about 6 g to about 9 g 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein: about 50 g to about 70 g catalytic reagent.
9 . A method of fabricating a portable detection kit of claim 1 , comprising:
preparing a dry mixture including 3′,3″,5′,5″-Tetraiodophenolsulfonephthalein and a dry catalytic reagent;
affixing the dry mixture to a solid support carrier to form a reaction zone thereon, thereby forming the portable detection kit of claim 1 .