IP Library › Granted Patent US 12,521,171
Granted Patent B2
US 12,521,171 · App. 16/550,160 · Granted Jan 13, 2026

Macerator for intracranial surgery

Inventors: Ross Tsukashima (Irvine, CA); Peter G. Davis (Irvine, CA); Matthew Scott Lake (Irvine, CA)
Assignee: Rebound Therapeutics Corporation
A61B18/148A61B2017/320024A61B2017/320032A61B2017/32007A61B2017/320084A61B2017/320716A61B17/320758A61B2017/320775A61B17/320783A61B2018/00446A61B2018/00595A61B2018/00642A61B2018/00672A61B2018/00875A61B2090/065A61B2217/005A61B2218/007
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Quick Facts
Patent No.
US 12,521,171
App. No.
16/550,160
Granted
Jan 13, 2026
Kind
B2
Abstract

A tool for treating hematoma in the brain, and other tissue in the body, especially suited for use through a cannula. The tool may include a cautery probe for sealing blood vessels in the brain, and a macerating structure for disrupting a hematoma, and aspiration features for removing macerated hematoma debris from the body.

Claims (16)

1 . A device for removal of body tissue, said device comprising:

an elongate probe comprising a first tube with a distal end and a proximal end, said distal end configured for insertion into a surgical space in a patient;

a side-facing aperture located on a side wall of the first tube near the distal end of the first tube;

a macerator assembly comprising a rod having a proximal end and a distal end and establishing a longitudinal center line of the macerator assembly, and a macerator structure disposed at the distal end of the rod wherein

the macerator structure is disposed within the first tube, longitudinally aligned with the side-facing aperture and rotatable within the probe and operable to disrupt body tissue proximate the side-facing aperture, wherein said macerator structure comprises a first flat blade, extending radially outwardly from the longitudinal center line, said blade having a width which closely matches an inner radius of the first tube.

2 . The device of claim 1 , wherein the probe has a lumen extending from the proximal end of the first tube to the side-facing aperture, and a vacuum source in fluid communication with the side-facing aperture through said a lumen.

3 . The device of claim 1 , wherein the macerating structure further comprises a second flat blade, disposed on the distal end of the rod and co-planar with the first flat blade, and also having a width corresponding to the inner radius of the probe, such that the macerating structure has a width which closely matches an inner diameter of the first tube.

4 . The device of claim 3 , wherein the first flat blade and second flat blade lie in a first plane, and the rod also lies in said first plane.

5 . The device of claim 3 , wherein the rod lies in a plane longitudinally dissecting the first tube, and the first blade and second blade lie in said plane longitudinally dissecting the first tube.

6 . The device of claim 1, 2 or 3 , wherein the probe further comprises a socket inside the probe, at the distal end of the first tube, and the macerating structure further comprises a distally extending projection which extends into the socket, said socket configured to provide a bearing surface to stabilize the macerator structure during rotation of the macerator structure.

7 . The device of claim 1, 2 or 3 , wherein the macerating structure comprises one or more notches in an outer edge of the blade.

8 . The device of claim 1, 2 or 3 , wherein the blades of the macerating structure comprises a straight radial outer edge.

9 . The device of claim 1, 2 or 3 , further comprising a radially extending projection disposed on the rod proximal to the macerating structure, said projections having a planar configuration and being disposed in a first plane longitudinally dissecting the first tube.

10 . The device of claim 1 wherein the flat blade of the macerating structure comprises a rectangular shape with a plurality of radial projections, and the width of the macerating structure, at said projections, closely matches the inner radius of the first tube.

11 . The device of claim 1 , wherein the first flat blade defines a first plane, and the rod lies in said first plane.

12 . The device of claim 1 , wherein the rod lies in a plane longitudinally dissecting the first tube, and the first blade lies in said plane longitudinally dissecting the first tube.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2019
From: TSUKASHIMA, ROSS; DAVIS, PETER G.; LAKE, MATTHEW SCOTT
To: REBOUND THERAPEUTICS CORPORATION
Reel/Frame 050158/0721 →
Continuity (2)
Provisional Application 62744445 · Oct 11, 2018
Related Publication 20200113619A1 · Apr 16, 2020
References Cited (66)
US 4522505A · Medd · 1985 [cited by examiner]
US 5226909A · Evans · 1993 [cited by examiner]
US 5242460A · Klein · 1993 [cited by examiner]
US 5487747A · Stagmann · 1996 [cited by examiner]
US 5529580A · Kusunoki · 1996 [cited by examiner]
US 5569178A · Henley · 1996 [cited by examiner]
US 5569284A · Young · 1996 [cited by examiner]
US 5823990A · Henley · 1998 [cited by examiner]
US 5857995A · Thomas · 1999 [cited by examiner]
US 5871454A · Majlessi · 1999 [cited by examiner]
US 5896971A · Hein · 1999 [cited by examiner]
US 6113593A · Tu et al. · 2000 [cited by applicant]
US 6152919A · Hakky · 2000 [cited by examiner]
US 10945758B1 · Davis · 2021 [cited by examiner]
US 20030045870A1 · Madsen · 2003 [cited by applicant]
US 20070010823A1 · Kucklick · 2007 [cited by examiner]
US 20080004647A1 · To · 2008 [cited by examiner]
US 20080021447A1 · Davison et al. · 2008 [cited by applicant]
US 20080172052A1 · Eder et al. · 2008 [cited by applicant]
US 20080177199A1 · Podhajsky · 2008 [cited by applicant]
US 20100030212A1 · Aramayo · 2010 [cited by applicant]
US 20100036312A1 · Krolik · 2010 [cited by examiner]
US 20100100098A1 · Norton · 2010 [cited by examiner]
US 20100228240A1 · Henriksson et al. · 2010 [cited by applicant]
US 20110218526A1 · Mathur · 2011 [cited by applicant]
US 20140031844A1 · Kusleika · 2014 [cited by examiner]
US 20140066929A1 · Mark et al. · 2014 [cited by applicant]
US 20140148830A1 · Bowman · 2014 [cited by examiner]
US 20140277039A1 · Liberatore · 2014 [cited by examiner]
US 20140330286A1 · Wallace · 2014 [cited by examiner]
US 20140371735A1 · Long · 2014 [cited by applicant]
US 20150088120A1 · Garcia et al. · 2015 [cited by applicant]
US 20150305765A1 · Fojtik et al. · 2015 [cited by applicant]
US 20150351836A1 · Prutchi · 2015 [cited by applicant]
US 20180353199A1 · Tada · 2018 [cited by examiner]
US 20190125391A1 · Palushi · 2019 [cited by examiner]
US 20190142452A1 · Trosper · 2019 [cited by examiner]
US 20190262031A1 · Efremkin · 2019 [cited by examiner]
US 20190357936A1 · To · 2019 [cited by examiner]
US 20220000507A1 · Hauser · 2022 [cited by examiner]
CN 106470618 · 2017 [cited by applicant]
EP 0403402A1 · 1990 [cited by examiner]
JP 2010525867 · 2010 [cited by applicant]
JP 2011045756 · 2011 [cited by applicant]
JP 2011131061 · 2011 [cited by applicant]
JP 2013519438 · 2013 [cited by applicant]
JP 2015119895 · 2015 [cited by applicant]
JP 2015532604 · 2015 [cited by applicant]
JP 2016147018 · 2016 [cited by applicant]
WO WO0007507 · 2000 [cited by applicant]
WO WO2007028151 · 2007 [cited by applicant]
WO WO2017201203 · 2017 [cited by applicant]
WO WO2018035366 · 2018 [cited by applicant]
International Search Report from International Application No. PCT/US2019/054804 dated Jan. 23, 2020. [cited by applicant]
Partial Supplementary European Search Report dated Jun. 15, 2022 from European Patent Application No. 19870985.9. [cited by applicant]
Notification of Reasons for Refusal dated Jun. 20, 2023 from corresponding JP Application 2021-520189. [cited by applicant]
Notification of Reasons for Refusal dated Feb. 6, 2024 from Japanese Patent Application No. 2021-520189. [cited by applicant]
Office Action dated Nov. 22, 2023 from Chinese Application No. 201980074205.5. [cited by applicant]
Office Action dated Apr. 11, 2025 from European Patent Application No. 19870985.9. [cited by applicant]
McCann, et al., Variation in reported Human Head Tissue Electrical Conductivity Values, Brain Topography, Human Sciences Press, vol. 32, May 3, 2019. [cited by applicant]
Examination Report No. 2 dated Aug. 5, 2024 from Australian Patent Application No. 2019357958. [cited by applicant]
Office Action dated Jul. 1, 2024 from Chinese Patent Application No. 201980074205.5. [cited by applicant]
Office Action dated Jul. 24, 2024 from Korean Patent Application No. 10-2021-7014131. [cited by applicant]
Notification of Reasons for Refusal dated Nov. 12, 2024 from Japanese Patent Application No. 2023-183133. [cited by applicant]
Examination Report No. 1 dated May 28, 2024 from Australian Patent Application 2019357958. [cited by applicant]
Notice of Allowance dated Feb. 27, 2025 from Korean Patent Application No. 1020217014131. [cited by applicant]