IP Library › Granted Patent US 12,544,264
Granted Patent B2
US 12,544,264 · App. 18/124,874 · Granted Feb 10, 2026

Intelligent topographic corneal procedure advisor

Inventor: Mark Lobanoff (North Oaks, MN)
Assignee: ALCON INC.
A61F9/00806A61B3/1035A61B3/107G06T7/0012G06T7/60A61B3/158A61F2009/00844A61F2009/00859A61F2009/00872A61F2009/0088A61F2009/00882A61F2009/00897
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Quick Facts
Patent No.
US 12,544,264
App. No.
18/124,874
Granted
Feb 10, 2026
Kind
B2
Abstract

Generation of treatment recommendations for topographic-based excimer laser surgical procedures is described that includes generating accurate cylinder compensation and spherical compensation values that are adjusted to compensate for unique characteristics of advanced topographic-based excimer laser surgical systems. Generating treatment recommendations generally includes determining a topographic vector from a topographic corneal map of the eye, determining a posterior astigmatism vector and an anterior astigmatism vector for the eye, and generating an interior astigmatism vector using the topographic vector, the posterior astigmatism vector, the anterior astigmatism vector, and a manifest astigmatism vector. In various embodiments, the cylinder compensation is generated using the interior astigmatism vector and the posterior astigmatism vector, and the spherical compensation is generated using an initial spherical compensation modified by a topographic addback modifier and a cylinder addback modifier.

Claims (46)

1 . A method for excimer laser treatments for a corneal surgical procedure on an eye, the method comprising:

receiving a topographic corneal map of the eye;

determining a topographic vector from the topographic corneal map of the eye;

determining a posterior astigmatism vector and an anterior astigmatism vector for the eye;

generating an interior astigmatism vector using the topographic vector, the posterior astigmatism vector, the anterior astigmatism vector, and a manifest astigmatism vector;

generating a cylinder compensation of a treatment recommendation using the interior astigmatism vector and the posterior astigmatism vector;

generating a spherical compensation of the treatment recommendation using an initial spherical compensation modified by a topographic addback modifier and a cylinder addback modifier; and

utilizing an excimer laser to perform a treatment based on the treatment recommendation, the cylinder compensation, and the spherical compensation.

2 . The method of claim 1 , wherein the topographic addback modifier is a value indicating a refractive effect of a difference between a height of a highest talus and an amount of tissue to be removed from the center of the cornea.

3 . The method of claim 1 , wherein the cylinder addback modifier is a value of one half a difference between a magnitude of the manifest astigmatism vector and a magnitude of the cylinder compensation.

4 . The method of claim 1 , wherein the topographic corneal map is determined by an optical measurement device.

5 . The method of claim 1 , wherein the topographic vector indicates a magnitude and a direction of an optical effect of a corneal talus.

6 . The method of claim 1 , wherein the initial spherical compensation is further modified by a nomogram addback modifier, where the nomogram addback modifier is based on a best-fit regression model of achieved correction versus attempted correction.

7 . The method of claim 1 , wherein the method further comprises:

receiving a plurality of inputs including the topographic corneal map, the posterior astigmatism vector, the anterior astigmatism vector, and the initial spherical compensation.

8 . The method of claim 7 , wherein the plurality of inputs are generated using topography guided LASIK software.

9 . The method of claim 1 , wherein the topographic vector is generated using Geographic Imaging System (GIS) processing of the topographic corneal map.

10 . The method of claim 1 , wherein the topographic vector is one of a set of one or more topographic vectors determined from the topographic corneal map of the eye, each of the set of topographic vectors indicating a magnitude and a direction of an optical effect of a corneal talus.

11 . A computer program product for generating a cylinder compensation and a spherical compensation for a corneal surgical procedure on an eye wherein the computer program product including a readable storage medium that is not a transitory signal per se, the program product including instructions executable by one or more processors to cause the one or more processors to perform a method comprising:

determining a topographic vector from a topographic corneal map of the eye, the topographic vector indicating a magnitude and a direction of an optical effect of a corneal talus, wherein the topographic corneal map is determined by a topographic-based LASIK treatment system including an optical measurement device;

determining a posterior astigmatism vector and an anterior astigmatism vector for the eye;

generating an interior astigmatism vector using the topographic vector, the posterior astigmatism vector, the anterior astigmatism vector, and a manifest astigmatism vector;

generating the cylinder compensation of a treatment recommendation using the interior astigmatism vector and the posterior astigmatism vector; and

generating the spherical compensation of the treatment recommendation using an initial spherical compensation modified by a topographic addback modifier and a cylinder addback modifier, where the topographic addback modifier is a value indicating a refractive effect of a difference between a height of a highest talus and an amount of tissue to be removed from the center of the cornea, and where the cylinder addback modifier is a value of one half a difference between a magnitude of the manifest astigmatism vector and a magnitude of the cylinder compensation; and

generating instructions executable by an excimer laser to perform a treatment based on the treatment recommendation, the cylinder compensation, and the spherical compensation.

12 . The computer program product of claim 11 , wherein the program product instructions cause the method to further comprise:

receiving a plurality of inputs including the topographic corneal map, the posterior astigmatism vector, the anterior astigmatism vector, and the initial spherical compensation, where the plurality of inputs are generated using topography guided LASIK software.

13 . A system for generating improved treatment recommendations for corneal procedures on an eye, the system comprising:

a display;

a processor; and

a computer readable storage medium having program instructions embodied therewith, wherein the computer readable storage medium is not a transitory signal per se, the program instructions executable by the processor to cause the processor to:

receive a topographic corneal map, a posterior astigmatism vector, an anterior astigmatism vector, an initial spherical compensation, an initial set of cylinder compensation values, and a manifest astigmatism vector for the eye;

determine a topographic vector from the topographic corneal map of the eye;

generate an interior astigmatism vector using the topographic vector, the posterior astigmatism vector, the anterior astigmatism vector, and the manifest astigmatism vector;

generate a cylinder compensation for the initial set of cylinder compensation values using the interior astigmatism vector and the posterior astigmatism vector;

generate a spherical compensation for the initial spherical compensation using the initial spherical compensation modified by a topographic addback modifier and a cylinder addback modifier; and

output, to the display, a visual representation of a treatment recommendation including the cylinder compensation and the spherical compensation; and

generating instructions executable by an excimer laser to perform a treatment based on the treatment recommendation, the cylinder compensation, and the spherical compensation.

14 . The system of claim 13 , wherein the topographic vector indicates a magnitude and a direction of an optical effect of a corneal talus.

15 . The system of claim 13 , wherein the topographic addback modifier is a value indicating a refractive effect of a difference between a height of a highest talus and an amount of tissue to be removed from the center of the cornea.

16 . The system of claim 13 , wherein the cylinder addback modifier is a value of one half a difference between a magnitude of the manifest astigmatism vector and a magnitude of the cylinder compensation.

17 . The system of claim 13 , wherein the program instructions are executable by the processor to further cause the processor to:

receive a plurality of inputs including the topographic corneal map, the posterior astigmatism vector, the anterior astigmatism vector, and the initial spherical compensation.

18 . The system of claim 17 , wherein the plurality of inputs are generated using topography guided LASIK software.

19 . The system of claim 13 , wherein the topographic vector is one of a set of one or more topographic vectors determined from the topographic corneal map of the eye.

20 . The system of claim 19 , wherein each of the set of topographic vectors indicates a magnitude and a direction of an optical effect of a corneal talus.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2025
From: LOBANOFF, MARK
To: PHORCIDES, LLC
Reel/Frame 070359/0359 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2025
From: PHORCIDES, LLC
To: ALCON RESEARCH, LLC
Reel/Frame 070359/0494 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2025
From: ALCON RESEARCH, LLC
To: ALCON INC.
Reel/Frame 070359/0583 →
Continuity (4)
Continuation 16523198 · Jul 26, 2019
Provisional Application 62798162 · Jan 29, 2019
Provisional Application 62770045 · Nov 20, 2018
Related Publication 20240041653A1 · Feb 8, 2024
References Cited (1)
WO WO2017091200A1 · 2017 [cited by examiner]