Granted Patent B2

US 12,558,220 · App. 17/592,856 · Granted Feb 24, 2026

Inventors: Valavanur A. Subramanian (New York, NY); Gene Reis (San Jose, CA); Maurice Buchbinder (La Jolla, CA); Tim MacNeil (Nashville, TN)

Assignee: Heart Repair Technologies, Inc.

A61F2/2454A61F2210/0014A61F2220/0008A61F2230/0017

Abstract

Claims (26)

1 . A transvalvular implant comprising:

an elongate body having a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion connected to the first end and the second end, wherein the central portion comprises an arcuate shape, wherein the elongate body tapers from a minimum width at the first end and second end to a maximum width at the central portion, wherein the elongate body comprises of a generally diamond shape,

the elongate body consisting of single length of wire, wherein the elongate body forms a continuous outline wherein a starting point and an ending point of the single length of wire are connected with a weld, wherein the first anchoring portion of the elongate body comprises a first eyelet and the second anchoring portion comprises a second eyelet, wherein the first eyelet comprises stacked coils which enclose a first eyelet opening, wherein the second eyelet comprises stacked coils which enclose a second eyelet opening, wherein the elongate body comprises a central opening, wherein the central opening comprises a generally diamond shape, wherein the transvalvular implant does not obstruct the flow of blood through the central opening;

a first helical anchor comprising a first post, wherein the first post is configured to extend through the first eyelet opening of the first eyelet;

a first locking clip configured to lock with the first post above the elongate body;

a second helical anchor comprising a second post, wherein the second post is configured to extend through the second eyelet opening of the second eyelet; and

a second locking clip configured to lock with the second post above the elongate body.

2 . The transvalvular implant of claim 1 , wherein the central portion is configured to be displaced transversely from an intraannular plane which includes a valve annulus and is transverse to a direction of blood flow when the elongate body is attached to the valve annulus.

3 . The transvalvular implant of claim 1 , wherein the first end and the second end are configured to be attached to a mitral valve annulus within an intraannular plane and the central portion is configured to be convex in a direction of outflow to support valve leaflets at a point displaced toward a ventricle from the intraannular plane.

4 . The transvalvular implant of claim 1 , wherein the first end and the second end are configured to be attached to a tricuspid valve annulus within an intraannular plane and the central portion is configured to be convex.

5 . The transvalvular implant of claim 1 , wherein the first end and the second end are configured to reside on a generally septal-lateral axis transverse to coaptive edges of valve leaflets when the elongate body is attached to a valve annulus.

6 . The transvalvular implant of claim 1 , wherein the transvalvular implant is configured for straddling a mitral valve orifice in a septal lateral diameter of a mitral valve annulus.

7 . The transvalvular implant of claim 1 , wherein the transvalvular implant is configured for the treatment of mitral valve regurgitation caused by dilatation of a mitral valve annulus and deformation of mitral valve leaflets or the treatment of tricuspid valve regurgitation caused by dilatation of a tricuspid valve annulus and deformation of tricuspid valve leaflets.

8 . The transvalvular implant of claim 1 , wherein a first tether extends from the first post, wherein the first tether is configured to be threaded through the first eyelet opening of the first eyelet of the first anchoring portion.

9 . The transvalvular implant of claim 1 , wherein the elongate body comprises stainless steel or nitinol.

10 . The transvalvular implant of claim 1 , wherein the elongate body comprises two planes of symmetry.

11 . The transvalvular implant of claim 1 , wherein transvalvular implant is wider toward a center or midpoint.

12 . The transvalvular implant of claim 1 , wherein the central opening extends along a majority of a length of the transvalvular implant.

13 . The transvalvular implant of claim 1 , wherein the central opening is uncoated.

14 . The transvalvular implant of claim 1 , wherein the central opening is enclosed by the elongate body.

15 . The transvalvular implant of claim 1 , wherein the central opening is uncovered.

16 . The transvalvular implant of claim 8 , wherein the first locking clip is configured to slide along the first tether to the first post.

17 . The transvalvular implant of claim 8 , wherein a second tether extends from the second post, wherein the second tether is configured to be threaded through the second eyelet opening of the second eyelet of the second anchoring portion.

18 . The transvalvular implant of claim 1 , wherein the first eyelet comprises three stacked coils.

19 . The transvalvular implant of claim 1 , wherein the first locking clip forms a friction fit with the first post of the first helical anchor.

20 . The transvalvular implant of claim 1 , wherein the first post comprises a groove shaped to accommodate the first locking clip.

Assignments (1)

Continuity (3)

References Cited (305)