IP Library Granted Patent US 12,559,776
Granted Patent B2
US 12,559,776 · App. 18/278,976 · Granted Feb 24, 2026

Chemical and biological integrated degradation process for polyethylene terephthalate (PET), for recycling pet

Inventors: Kyoung Heon Kim (Seoul, KR); Dong Hyun Kim (Seoul, KR); Dong Oh Han (Seoul, KR); Jae Kyun Kim (Seoul, KR)
Assignee: Korea University Research and Business Foundation
C12P7/42C07C67/297
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Quick Facts
Patent No.
US 12,559,776
App. No.
18/278,976
Granted
Feb 24, 2026
Kind
B2
Abstract

The present invention relates to a chemical and biological integrated degradation process for PET, for recycling PET, and, more specifically, the present invention provides a PET upcycling technique for producing a high-value product via a chemical pretreatment process of PET, a TPA and EG production process using an enzyme, and a process for converting TPA and EG to PCA and GLA, respectively.

Claims (11)

1 . A method for depolymerizing polyethylene terephthalate (PET) into an oligomer using glycolysis as a process, with betaine acting as the catalyst.

2 . A method of producing a high-value compound from polyethylene terephthalate (PET), comprising:

producing bis(2-hydroxyethyl) terephthalate (BHET) through glycolysis of PET in the presence of betaine as a catalyst;

depolymerizing the produced BHET into terephthalic acid and ethylene glycol via mono(2-hydroxyethyl) terephthalate (MHET) through enzymatic hydrolysis; and

converting the terephthalic acid into protocatechuic acid (PCA) through bioconversion in the presence of a biocatalyst, or converting the ethylene glycol into glycolic acid (GLA) through fermentation.

3 . The method of claim 1 , wherein the glycolysis of PET is performed by applying microwaves in the presence of an ethylene glycol solvent.

4 . The method of claim 2 , wherein the BHET is hydrolyzed into MHET by IsPETase, and the MHET is hydrolyzed into terephthalic acid and ethylene glycol by IsMHETase.

5 . The method of claim 4 , wherein the IsPETase consists of the base sequence represented by SEQ ID NO: 1, and the IsMHETase consists of the base sequence represented by SEQ ID NO: 2.

6 . The method of claim 2 , wherein the bioconversion of terephthalic acid into protocatechuic acid is performed using microorganisms expressing terephthalic acid 1,2-dioxygenase and 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase as biocatalysts.

7 . The method of claim 2 , wherein the fermentation of ethylene glycol is performed using ethylene glycol-fermenting microorganisms including one or more selected from the group consisting of Gluconobacter oxydans ( G. oxydans ) KCCM 40109, Clostridium glycolicums , and Pseudomonas putida.

8 . The method of claim 2 , wherein the glycolysis of PET is performed by applying microwaves in the presence of an ethylene glycol solvent.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2024
From: KIM, KYOUNG HEON; KIM, DONG HYON; KIM, JAE KYUN; HAN, DONG OH
To: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Reel/Frame 066731/0362 →
Priority Claims (1)
KR 10-2021-0026729 · Feb 26, 2021 · national
Continuity (2)
Related Publication 20240132922A1 · Apr 25, 2024
Related Publication 20240229084A9 · Jul 11, 2024
References Cited (11)
US 10508186B2 · Parrott · 2019 [cited by applicant]
US 20200048621A1 · Kim · 2020 [cited by applicant]
KR 1020200067665A · 2020 [cited by applicant]
KR 1020200119213A · 2020 [cited by applicant]
WO 2018168679A1 · 2018 [cited by applicant]
WO 2019053392A1 · 2019 [cited by applicant]
Office Action issued Apr. 18, 2024 in Korean Application No. 10-2022-0025037. [cited by applicant]
Jian Sun, et al., “Solubilization and Upgrading of High Polyethylene Terephthalate Loadings in a Low-Costing Bifunctional Ionic Liquid”, ChemSusChem, 2018, vol. 11, pp. 781-792 (12 pages total). [cited by applicant]
Brandon C.Knott et al., “Characterization and engineering of a two-enzyme system for plastics depolymerization”, Proceedings of the National Academy of Sciences, Oct. 13, 2020, pp. 25476-25485, vol. 117, No. 41. [cited by applicant]
Dong Hyun Kim et al., “One-Pot Chemo-bioprocess of PET Depolymerization and Recycling Enabled by a Biocompatible Catalyst, Betaine”, American Chamical Society Catalysis, Nov. 2021, pp. 3996-4008. [cited by applicant]
International Search Report for PCT/KR2022/002784 dated Jun. 9, 2022. [cited by applicant]