IP Library › Granted Patent US 12,564,719
Granted Patent B2
US 12,564,719 · App. 18/422,303 · Granted Mar 3, 2026

Selection of parameters for electrical stimulation

Inventor: Xin Su (Plymouth, MN)
Assignee: Medtronic, Inc.
A61N1/3615A61N1/025A61N1/36175A61N1/36192A61N1/36196A61N1/37247
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Quick Facts
Patent No.
US 12,564,719
App. No.
18/422,303
Granted
Mar 3, 2026
Kind
B2
Abstract

Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system may include processing circuitry configured to control a medical device to deliver a first electrical stimulation according to a first value of a first stimulation parameter of the plurality of stimulation parameters and a first value of a second parameter of the plurality of stimulation parameters, receive an input representative of an efficacy of the first electrical stimulation delivered to the patient according to the first value of the first stimulation parameter and the first value of the second parameter, select, based on the input and the relationship between the plurality of stimulation parameters, a second value of at least one of the first stimulation parameter or the second stimulation parameter, and control the medical device to deliver a second electrical stimulation according to the second value.

Claims (40)

1 . A system comprising:

a memory configured to store a relationship between pulse frequency and one or more other stimulation parameters; and

processing circuitry configured to:

control a medical device to deliver a first electrical stimulation according to a first pulse frequency value;

receive information representative of an evoked compound action potential (ECAP) sensed in response to the first electrical stimulation;

determine, based on the relationship and the information representative of the ECAP, a second pulse frequency value higher than the first pulse frequency value and a value of the one or more other stimulation parameters corresponding to the second pulse frequency value; and

control the medical device to deliver a second electrical stimulation according to the second pulse frequency value and the value of the one or more other stimulation parameters.

2 . The system of claim 1 , wherein the one or more other stimulation parameters comprises a pulse width.

3 . The system of claim 1 , wherein the one or more other stimulation parameters comprises an amplitude.

4 . The system of claim 1 , wherein the information representative of the ECAP comprises an ECAP characteristic value, and wherein the processing circuitry is configured to determine the second pulse frequency value and the value of the one or more other stimulation parameters such that the second electrical stimulation elicits the ECAP characteristic value.

5 . The system of claim 1 , wherein the relationship comprises a strength-duration curve between the pulse frequency and a pulse width.

6 . The system of claim 1 , wherein the medical device is configured to sense the ECAP, and wherein the medical device is configured to sense the ECAP elicited from the first electrical stimulation at the first pulse frequency value instead of the second electrical stimulation at the second pulse frequency value.

7 . The system of claim 1 , wherein the first pulse frequency is lower than 1 kHz, and wherein the second pulse frequency is in a range from 1 kHz to 10 KHz.

8 . The system of claim 1 , wherein the relationship is a first relationship, and wherein the processing circuitry is configured to determine a second relationship between an ECAP characteristic and at least one of the pulse frequency or the one or more stimulation parameters, and wherein the processing circuitry is configured to select at least the second pulse frequency value or the value of the one or more stimulation parameters based upon on the second relationship and the received information representative of the ECAP.

9 . The system of claim 1 , further comprising:

a stimulation generator configured to generate the first electrical stimulation and the second electrical stimulation;

sensing circuitry configured to sense the ECAP; and

the medical device, wherein the medical device is configured to house the stimulation generator and the sensing circuitry and configured to be implanted in a patient.

10 . The system of claim 1 , wherein the first electrical stimulation and the second electrical stimulation is configured to provide spinal cord stimulation therapy that reduces pain of a patient.

11 . A method comprising:

storing a relationship between pulse frequency and one or more other stimulation parameters;

controlling, by processing circuitry, a medical device to deliver a first electrical stimulation according to a first pulse frequency value;

receiving, by the processing circuitry, information representative of an evoked compound action potential (ECAP) sensed in response to the first electrical stimulation;

determining, by the processing circuitry and based on the relationship and the information representative of the ECAP, a second pulse frequency value higher than the first pulse frequency value and a value of the one or more other stimulation parameters corresponding to the second pulse frequency value; and

controlling, by the processing circuitry, the medical device to deliver a second electrical stimulation according to the second pulse frequency value and the value of the one or more other stimulation parameters.

12 . The method of claim 11 , wherein the one or more other stimulation parameters comprises a pulse width.

13 . The method of claim 11 , wherein the one or more other stimulation parameters comprises an amplitude.

14 . The method of claim 11 , wherein the information representative of the ECAP comprises an ECAP characteristic value, and wherein determining the second pulse frequency value and the value of the one or more other stimulation parameters comprises determine the second pulse frequency value and the value of the one or more other stimulation parameters such that the second electrical stimulation elicits the ECAP characteristic value.

15 . The method of claim 11 , wherein the relationship comprises a strength-duration curve between the pulse frequency and a pulse width.

16 . The method of claim 11 , further comprising sensing, by the medical device, the ECAP elicited from the first electrical stimulation at the first pulse frequency value instead of the second electrical stimulation at the second pulse frequency value.

17 . The method of claim 11 , wherein the first pulse frequency is lower than 1 kHz, and wherein the second pulse frequency is in a range from 1 kHz to 10 kHz.

18 . The method of claim 11 , wherein the relationship is a first relationship, and wherein the method further comprises determining a second relationship between an ECAP characteristic and at least one of the pulse frequency or the one or more stimulation parameters, and wherein selecting at least the second pulse frequency value or the value of the one or more stimulation parameters comprises selecting at least the second pulse frequency value or the value of the one or more stimulation parameters based upon on the second relationship and the received information representative of the ECAP.

19 . The method of claim 11 , wherein the first electrical stimulation and the second electrical stimulation is configured to provide spinal cord stimulation therapy that reduces pain of a patient.

20 . A computer-readable storage medium comprising instructions that, when executed, causes processing circuitry to:

a memory configured to store a relationship between a pulse frequency and one or more other stimulation parameters; and

processing circuitry configured to:

control a medical device to deliver a first electrical stimulation according to a first pulse frequency value;

receive information representative of an evoked compound action potential (ECAP) sensed in response to the first electrical stimulation;

determine, based on a relationship and the information representative of the ECAP, a second pulse frequency value higher than the first pulse frequency value and a value of the one or more other stimulation parameters corresponding to the second pulse frequency value, wherein the relationship is stored in memory and between a pulse frequency and one or more other stimulation parameters; and

control the medical device to deliver a second electrical stimulation according to the second pulse frequency value and the value of the one or more other stimulation parameters.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2024
From: SU, XIN
To: MEDTRONIC, INC.
Reel/Frame 066245/0037 →
Continuity (3)
Continuation 17653670 · Mar 7, 2022
Continuation 16215072 · Dec 10, 2018
Related Publication 20240157150A1 · May 16, 2024
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