Medical device and method for detecting atrioventricular block
A medical device includes a motion sensor configured to sense a motion signal. The medical device includes a control circuit configured to determine at least one ventricular event metric from the motion signal sensed over multiple of atrial cycles, determine that the ventricular event metric meets atrioventricular block criteria and generate an output in response to determining the atrioventricular block.
1 . A medical device comprising:
a motion sensor configured to sense a motion signal;
a control circuit configured to:
for each atrial cycle of a plurality of atrial cycles:
determine a fiducial point of the motion signal;
determine an atrioventricular activation time from an atrial event to the fiducial point of the motion signal;
determine a ventricular event metric based on the atrioventricular activation times determined for the plurality of atrial cycles;
determine that the ventricular event metric meets output criteria; and
generate an output comprising a pacing therapy adjustment in response to determining that the ventricular event metric meets the output criteria;
a memory configured to store the generated output; and
a therapy delivery circuit configured to deliver a pacing therapy according to the pacing therapy adjustment.
2 . The medical device of claim 1 wherein the control circuit is further configured to determine the ventricular event metric by determining a trend of the atrioventricular activation time based on the atrioventricular activation times.
3 . The medical device of claim 1 wherein the control circuit is further configured to determine the ventricular event metric based on the atrioventricular activation times by determining a variability of the atrioventricular activation times.
4 . The medical device of claim 1 wherein the control circuit is further configured to:
compare the atrioventricular activation times to a first threshold activation time;
count each atrioventricular activation time that is greater than the first threshold activation time as an atrioventricular block cycle; and
determine the ventricular event metric as the count of the atrioventricular block cycles.
5 . The medical device of claim 4 wherein the control circuit is further configured to:
compare the atrioventricular activation times to a second threshold activation time that is less than the first threshold activation time; and
count each atrioventricular activation time that is less than the second threshold activation time as an atrioventricular block cycle.
6 . The medical device of claim 1 wherein the control circuit is further configured to:
determine the ventricular activity metric by:
determining a representative value of the atrioventricular activation times;
determining a range of the atrioventricular activation times; and
determine that the ventricular activity metric meets the output criteria when the representative value is greater than a threshold atrioventricular activation time and the range is greater than a threshold range.
7 . The medical device of claim 1 wherein the control circuit is further configured to determine the ventricular activity metric by determining a sum of differences between successive atrioventricular activation times of the determined atrioventricular activation times.
8 . The medical device of claim 1 wherein the control circuit is further configured to determine the fiducial point of the motion signal as a maximum peak amplitude of the motion signal sensed during the respective atrial cycle.
9 . The medical device of claim 1 wherein the control circuit is further configured to:
detect a condition for monitoring for atrioventricular block; and
determine the ventricular activation times in response to detecting the condition for monitoring for atrioventricular block.
10 . The medical device of claim 1 further comprising:
a sensing circuit configured to sense a cardiac electrical signal; and
a telemetry circuit;
wherein the control circuit is further configured to store an episode of at least one of the cardiac electrical signal and the motion signal in response to determining that the ventricular event metric meets the atrioventricular block criteria; and
the telemetry circuit is configured to transmit the stored episode.
11 . A method comprising:
sensing a motion signal;
for each atrial cycle of a plurality of atrial cycles:
determining a fiducial point of the motion signal;
determining an atrioventricular activation time from an atrial event to the fiducial point of the motion signal;
determining a ventricular event metric based on the atrioventricular activation times determined for the plurality of atrial cycles;
determining that the ventricular event metric meets output criteria;
generating an output comprising a pacing therapy adjustment in response to determining that the ventricular event metric meets the output criteria;
storing the generated output in a memory; and
delivering a pacing therapy according to the pacing therapy adjustment.
12 . The method of claim 11 further comprising determining the ventricular event metric by determining a trend of the atrioventricular activation time based on the atrioventricular activation times.
13 . The method of claim 11 further comprising determining the ventricular event metric based on the atrioventricular activation times by determining a variability of the atrioventricular activation times.
14 . The method of claim 11 further comprising:
comparing the atrioventricular activation times to a first threshold activation time;
counting each atrioventricular activation time that is greater than the first threshold activation time as an atrioventricular block cycle; and
determining the ventricular event metric as the count of the atrioventricular block cycles.
15 . The method of claim 14 further comprising:
comparing the atrioventricular activation times to a second threshold activation time that is less than the first threshold activation time; and
counting each atrioventricular activation time that is less than the second threshold activation time as an atrioventricular block cycle.
16 . The method of claim 11 further comprising:
determining the ventricular activity metric by:
determining a representative value of the atrioventricular activation times;
determining a range of the atrioventricular activation times; and
determining that the ventricular activity metric meets the output criteria when the representative value is greater than a threshold atrioventricular activation time and the range is greater than a threshold range.
17 . The method of claim 11 further comprising determining the ventricular activity metric by determining a sum of differences between successive atrioventricular activation times of the determined atrioventricular activation times.
18 . The method of claim 11 further comprising determining the fiducial point of the motion signal as a maximum peak amplitude of the motion signal sensed during the respective atrial cycle.
19 . The method of claim 11 further comprising:
detecting a condition for monitoring for atrioventricular block; and
determining the ventricular activation times in response to detecting the condition for monitoring for atrioventricular block.
20 . The method of claim 11 further comprising:
sensing a cardiac electrical signal;
storing an episode of at least one of the cardiac electrical signal and the motion signal in response to determining that the ventricular event metric meets the atrioventricular block criteria; and
transmitting the stored episode.