Stents, systems, and methods for gastrointestinal tract treatment
The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.
1 . A stent, comprising:
a tubular scaffold having a longitudinal extent with a first end opposite a second end and an anchoring region at an anchoring position along the longitudinal extent, and defining a lumen extending between the first end and the second end; and
a liner extending at least partially along the tubular scaffold;
wherein:
the anchoring region of the tubular scaffold has a shape distinct from the shape of a region of the tubular scaffold proximal to the anchoring region and a region of the tubular scaffold distal to the anchoring region; and
a portion of the liner located along the longitudinal extent of the tubular scaffold at the same position as the anchoring position is spaced radially-inwardly from and within the anchoring region of the tubular scaffold to promote tissue ingrowth with the anchoring region of the tubular scaffold.
2 . The stent of claim 1 , wherein the anchoring region is a medial anchoring region along the medial section of the scaffold to promote tissue ingrowth with the medial section.
3 . The stent of claim 2 , wherein the medial anchoring region is provided at an expanded portion of the medial section, and wherein the expanded portion has a diameter greater than a diameter of the medial section.
4 . The stent of claim 3 , wherein the liner is radially-inwardly spaced from and within the expanded portion to promote tissue ingrowth with the expanded portion.
5 . The stent of claim 1 , wherein the anchoring region is located along a sloped portion of a flared section of the tubular scaffold, and wherein the sloped portion extends away from a central longitudinal axis extending through the lumen.
6 . The stent of claim 1 , wherein the medial section has a substantially uniform diameter.
7 . The stent of claim 1 , wherein:
the tubular scaffold comprises a flared section and a medial section extending longitudinally from the flared section; and
the anchoring region is located along the flared section.
8 . A system, comprising:
a stent comprising:
a tubular scaffold having a longitudinal extent with a first end opposite a second end and an anchoring region along the longitudinal extent, and defining a lumen extending between the first end and the second end; and
a liner extending at least partially along the tubular scaffold, wherein a portion of the liner located along the longitudinal extent of the tubular scaffold at the same position as the anchoring region of the tubular scaffold is spaced radially-inwardly from and within the anchoring region to promote tissue ingrowth with the anchoring region and between the regions of the tubular scaffold proximal and distal to the anchoring region; and
a sheath extending from the second end of the tubular scaffold, the sheath having a proximal end opposite a distal end, wherein a lumen extends between the proximal end and the distal end.
9 . The system of claim 8 , further comprising a second stent coupled to the distal end of the sheath.
10 . The system of claim 9 , the second stent comprising:
a second tubular scaffold; and
a second liner extending partially along the second tubular scaffold.
11 . The system of claim 10 , wherein:
the first tubular scaffold comprises a flared section and a medial section extending longitudinally from the flared section;
the second tubular scaffold comprises a flared section and a medial section extending from the flared section; and
the liner extending at least partially along the tubular scaffold is spaced from and within an anchoring region along the flared section of the tubular scaffold to promote tissue ingrowth with the anchoring region.
12 . The system of claim 8 , wherein the anchoring region is a medial anchoring region along the medial section of the scaffold to promote tissue ingrowth with the medial section.
13 . The stent of claim 8 , wherein the anchoring region is located along a sloped portion of a flared section of the tubular scaffold, and wherein the sloped portion extends away from a central longitudinal axis extending through the lumen.
14 . The stent of claim 8 , wherein the medial section includes an expanded portion, the expanded portion having a diameter greater than a diameter of the medial section.
15 . The stent of claim 14 , wherein the liner is radially-inwardly spaced from and within the expanded portion to promote tissue ingrowth with the expanded portion.
16 . The stent of claim 8 , wherein the sheath comprises a structural support element.
17 . A method, comprising:
deploying a system within a gastrointestinal (GI) tract of a patient, the system comprising:
a stent comprising a tubular scaffold having a longitudinal extent with a first end opposite a second end and an anchoring region at an anchoring position along the longitudinal extent, and defining a lumen extending between the first end and the second end; and
a liner extending at least partially along the tubular scaffold, wherein a portion of the liner located along the longitudinal extent of the tubular scaffold at the same position as the anchoring position is spaced radially-inwardly from and within the anchoring region of the tubular scaffold such that the anchoring region is exposed to the GI tract to promote tissue ingrowth between the anchoring region of the tubular scaffold and the GI tract; and
positioning the tubular scaffold in the GI tract with the anchoring region of the tubular scaffold adjacent tissue in the GI tract to promote tissue ingrowth therewith.
18 . The method of claim 17 , further comprising determining a location of the GI tract target site, wherein the GI tract target site corresponds to a leak of the GI tract.
19 . The method of claim 17 , further comprising bypassing a portion of the GI tract using a sheath extending from the second end of the tubular scaffold, the sheath having a proximal end opposite a distal end, wherein a lumen extends between the proximal and distal ends.
20 . The method of claim 19 , further comprising securing a second stent within the GI tract, the second stent coupled to the distal end of the sheath.