IP Library Granted Patent US 12,578,567
Granted Patent B2
US 12,578,567 · App. 18/598,307 · Granted Mar 17, 2026

Apparatus and methods for real-time image generation

Inventors: Ganesh Ramamoorthy (Andover, MA); Prasanth Perugupalli (Cary, NC)
Assignee: Pramana, Inc.
G02B21/361G02B21/26G02B21/32G02B21/34G02B21/365G02B21/368
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Quick Facts
Patent No.
US 12,578,567
App. No.
18/598,307
Granted
Mar 17, 2026
Kind
B2
Abstract

Aspects of present disclosure relate to real-time image generation. An exemplary apparatus for real time image generation includes at least an optical system, a slide port configured to hold a slide, an actuator mechanism mechanically connected to a mobile element, a user interface comprising an input interface and an output interface, at least a processor configured to: using the at least an optical system, capture a first image of the slide at a first position, modify the first image, using the output interface, display the first image to a user, using the input interface, receive a parameter set from the user.

Claims (36)

1 . An apparatus for real time image generation, the apparatus comprising:

at least an optical system;

a slide port configured to hold a slide;

an actuator mechanism mechanically connected to a mobile element;

a user interface;

at least a processor; and

a memory communicatively connected to the at least a processor, the memory containing instructions configuring the at least a processor to:

using the at least an optical system, capture a first image of the slide at a first position;

receive a first parameter set;

using the actuator mechanism, move the mobile element into a second position, wherein the second position is determined based on the first parameter set;

using the at least an optical system, capture a second image of the slide at the second position; and

using the user interface, display the second image to a user.

2 . The apparatus of claim 1 , wherein the first image comprises an image of the entire slide.

3 . The apparatus of claim 1 , wherein the second image comprises a plurality of images of an region of interest of the slide at differing focus depths for each image of the plurality of images.

4 . The apparatus of claim 1 , wherein the memory contains further instructions configuring the at least a processor to add an annotation to the second image based as a function of an annotation instruction.

5 . The apparatus of claim 1 , wherein the memory contains further instructions configuring the at least a processor to identify at least an artifact within the first image using a machine vision system.

6 . The apparatus of claim 5 , wherein the memory contains further instructions configuring the at least a processor to remove the at least an artifact from the first image.

7 . The apparatus of claim 1 , wherein the memory contains further instructions configuring the at least a processor to identify a second parameter set as a function of the first parameter set, wherein the second parameter set comprises a level of zoom associated with a region of interest of the slide.

8 . The apparatus of claim 1 , wherein the memory contains further instructions configuring the at least a processor to modify the second image, wherein modifying the second image comprises replacing at least a region of the first image with the second image to create a hybrid image.

9 . The apparatus of claim 1 , wherein moving the mobile element into the second position comprises setting a focus height of the at least an optical system based on a focus height specified by the first parameter set.

10 . The apparatus of claim 1 , wherein moving the mobile element into the second position comprises positioning, using the actuator mechanism, the at least an optical system relative to the slide such that a region of interest of the slide defined by the first parameter set is within a frame of the at least an optical sensor of the at least an optical system.

11 . A method for real time image generation, the method comprising:

capturing, by at least a processor, a first image of a slide at a first position using at least an optical system;

receiving, by the at least a processor, a first parameter set;

moving, by the at least a processor, a mobile element into a second position, wherein the second position is determined based on the first parameter set using an actuator mechanism;

capturing, by the at least a processor, a second image of the slide at the second position using at least an optical system; and

displaying, by the at least a processor, the second image to a user using a user interface.

12 . The method of claim 11 , wherein the first image comprises an image of the entire slide.

13 . The method of claim 11 , wherein the second image comprises a plurality of images of an region of interest of the slide at differing focus depths for each image of the plurality of images.

14 . The method of claim 11 , wherein method further comprises adding, by the at least a processor, an annotation to the second image based as a function of an annotation instruction.

15 . The method of claim 11 , wherein method further comprises identifying, by the at least a processor, at least an artifact within the first image using a machine vision system.

16 . The method of claim 15 , wherein method further comprises removing, by the at least a processor, the at least an artifact from the first image.

17 . The method of claim 11 , wherein method further comprises identifying, by the at least a processor, a second parameter set as a function of the first parameter set, wherein the second parameter set comprises a level of zoom associated with a region of interest within the slide.

18 . The method of claim 11 , wherein method further comprises modifying, by the at least a processor, the second image, wherein modifying the second image comprises replacing at least a region of the first image with the second image to create a hybrid image.

19 . The method of claim 11 , wherein moving the mobile element into the second position comprises setting a focus height of the at least an optical system based on a focus height specified by the first parameter set.

20 . The method of claim 11 , wherein moving the mobile element into the second position comprises positioning, using the actuator mechanism, the at least an optical system relative to the slide such that a region of interest of the slide defined by the first parameter set is within a frame of the at least an optical sensor of the at least an optical system.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2025
From: RAMAMOORTHY, GANESH; PERUGUPALLI, PRASANTH
To: PRAMANA, INC.
Reel/Frame 071902/0512 →
Continuity (2)
Continuation 18226100 · Jul 25, 2023
Related Publication 20250035907A1 · Jan 30, 2025
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