IP Library › Granted Patent US 12,583,855
Granted Patent B2
US 12,583,855 · App. 17/626,318 · Granted Mar 24, 2026

RET selective inhibitor, preparation method therefor and use thereof

Inventors: Zhihua Liu (Beijing, CN); Dechuang Yuan (Beijing, CN); Kuncheng Chen (Beijing, CN); Baokun Yuan (Beijing, CN); Ren Ren (Beijing, CN); Wangyang Min (Beijing, CN); Xijie Liu (Beijing, CN); Kai Zhang (Beijing, CN); Yongliang Sun (Beijing, CN); Chang Lu (Beijing, CN); Yinghui Sun (Beijing, CN)
Assignee: SHOUYAO HOLDINGS (BEIJING) CO., LTD.
C07D471/04C07D519/00
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Quick Facts
Patent No.
US 12,583,855
App. No.
17/626,318
Granted
Mar 24, 2026
Kind
B2
Abstract

The present invention provides an RET selective inhibitor and preparation method and use thereof; the present invention provides a compound of formula (1) and a pharmaceutically accepted salt, solvate, polymorph, or tautomer thereof, a composition comprising these compounds, and use of these compounds in the treatment of diseases related to RET.

Claims (2)

1 . A compound selected from below:

or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 11, 2022
From: LIU, ZHIHUA; YUAN, DECHUANG; CHEN, KUNCHENG; YUAN, BAOKUN; REN, REN; MIN, WANGYANG; LIU, XIJIE; ZHANG, KAI; SUN, YONGLIANG; LU, CHANG; SUN, YINGHUI
To: SHOUYAO HOLDINGS (BEIJING) CO., LTD.
Reel/Frame 058621/0855 →
Priority Claims (2)
CN 201910627353.7 · Jul 12, 2019 · national
CN 201910825867.3 · Sep 3, 2019 · national
Continuity (1)
Related Publication 20220289740A1 · Sep 15, 2022
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