IP Library › Granted Patent US 12,607,182
Granted Patent B2
US 12,607,182 · App. 19/071,580 · Granted Apr 21, 2026

Strain-actuated microfluidic pump sensor

Inventors: Ismail Emre Araci (San Jose, CA); Caroline Barbar Askar (San Jose, CA); Nick Cmager (Santa Clara, CA)
Assignee: Santa Clara University
F04B43/084F04B19/006F04B19/04
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Quick Facts
Patent No.
US 12,607,182
App. No.
19/071,580
Granted
Apr 21, 2026
Kind
B2
Abstract

A skin-strain-actuated microfluidic pump (SAMP) is provided that utilizes asymmetric aspect ratio of pumping channels for the recording of human activity in the fluidic domain.

Claims (9)

1 . A skin-strain-actuated microfluidic pump (SAMP), comprising:

(a) an actuator array of channels, wherein the channels are positioned more or less parallel to each other and fluidically connected capable of generating a reversible fluidic displacement caused by an in-plane strain;

(b) two asymmetric pumping channels fluidically connected to each other at a connection point, wherein the connection point is fluidically connected by a single channel to the actuator array of channels, and wherein cross-sections of each of the two asymmetric pumping channels are asymmetric from each other; and

(c) two liquid displacement quantification channels, wherein one of the two liquid displacement quantification channels is fluidically connected to one of the two asymmetric pumping channels, and the other of the liquid displacement quantification channels is fluidically connected to the other of the two asymmetric pumping channels,

wherein a difference in deformation characteristics of each of the two asymmetric pumping channels caused by the asymmetry of the cross-sections results in an asymmetric flow in the two asymmetric pumping channels.

2 . The skin-strain-actuated microfluidic pump as set forth in claim 1 , wherein the difference in the deformation characteristics of each of the two asymmetric pumping channels caused by the asymmetry of the cross-sections is defined as a ratio in hydraulic resistance for each of the two asymmetric pumping channels.

3 . The skin-strain-actuated microfluidic pump as set forth in claim 1 , wherein the cross-sections of the two asymmetric pumping channels have an aspect ratio defined by a height to a width ratio of the respective cross-sections, wherein a difference or asymmetry in the aspect ratios causes the difference in the deformation characteristics of each of the two asymmetric pumping channels caused by the asymmetry of the cross-sections.

4 . The skin-strain-actuated microfluidic pump as set forth in claim 1 , wherein the cross-sections of the two asymmetric pumping channels are circular, elliptical or triangular with dimensional asymmetry from one cross-section to the other cross-section.

5 . The skin-strain-actuated microfluidic pump as set forth in claim 1 , further comprising a working liquid flowing through the actuator array of channels, the two asymmetric pumping channels and the liquid displacement quantification channels.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2025
From: ARACI, ISMAIL EMRE; BARBAR ASKAR, CAROLINE; CMAGER, NICK
To: SANTA CLARA UNIVERSITY
Reel/Frame 070453/0567 →
Continuity (2)
Provisional Application 63565718 · Mar 15, 2024
Related Publication 20250290501A1 · Sep 18, 2025
References Cited (17)
US 1580479A · Frankenfield · 1926 [cited by examiner]
US 3148624A · Baldwin · 1964 [cited by examiner]
US 3630644A · Bellhouse · 1971 [cited by examiner]
US 5346369A · Miller, Jr. · 1994 [cited by examiner]
US 9395050B2 · Kornilovich · 2016 [cited by examiner]
US 9588100B2 · Appleyard · 2017 [cited by examiner]
US 11187224B2 · Xia · 2021 [cited by examiner]
US 11415503B2 · Appleyard · 2022 [cited by examiner]
US 20050133371A1 · Timperman · 2005 [cited by examiner]
US 20080166188A1 · Gilbert · 2008 [cited by examiner]
US 20150024373A1 · Xia · 2015 [cited by examiner]
US 20210106995A1 · Araci · 2021 [cited by examiner]
WO WO2020233791A1 · 2020 [cited by examiner]
Reeder et al., “Resettable skin interfaced microfluidic sweat collection devices with chemesthetic hydration feedback,” Nat Commun, vol. 10, No. 1, Dec. 2019, doi: 10.1038/s41467-019-13431-8. [cited by applicant]
Li et al., “Stretch-driven microfluidic chip for nucleic acid detection,” Biotechnol Bioeng, vol. 118, No. 9, pp. 3559-3568, Sep. 2021, doi: 10.1002/BIT.27839. [cited by applicant]
Mishra et al, “A Soft Wearable Microfluidic Patch with Finger-Actuated Pumps and Valves for On-Demand, Longitudinal, and Multianalyte Sweat Sensing,” ACS Sens, vol. 7, No. 10, pp. 3169-3180, Oct. 2022, doi: 10.1021/ACSS… [cited by applicant]
Liu et al., “Strain-Tunable Microfluidic Devices with Crack and Wrinkle Microvalves for Microsphere Screening and Fluidic Logic Gates,” ACS Appl Mater Interfaces, vol. 13, No. 31, pp. 36849-36858, Aug. 2021, doi: 10.102… [cited by applicant]