IP Library › Granted Patent US 12,622,784
Granted Patent B2
US 12,622,784 · App. 17/507,709 · Granted May 12, 2026

Heart valve repair

Inventors: Nima V. Nia (Mission Viejo, CA); Hengchu Cao (Irvine, CA); Bingquan Su (Irvine, CA); Douglas Thomas Dominick (Irvine, CA); Sakyasingh Tripathy (San Diego, CA)
Assignee: Edwards Lifesciences Corporation
A61F2/2463A61F2/2454A61F2/246A61F2220/0016A61F2220/0075
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Quick Facts
Patent No.
US 12,622,784
App. No.
17/507,709
Granted
May 12, 2026
Kind
B2
Abstract

A heart valve repair system includes an implantable device and a connector. The implantable device is configured to attach to at least two leaflets of a native heart valve of a patient and hold the at least two leaflets in a relatively fixed position. The connector is separate from the implantable device and includes first and second tissue anchors. The connector is configured to be attached to the at least two leaflets of the native valve when the at least two leaflets are held by the implantable device in the relatively fixed position. The implantable device is configured to be detached from the at least two leaflets and removed from the patient with the connector remaining attached to the at least two leaflets.

Claims (51)

1 . A heart valve repair system comprising:

an implantable device configured to attach to at least two leaflets of a native heart valve of a patient and hold the at least two leaflets in a relatively fixed position; and

a connector that is separate from the implantable device, the connector including first and second tissue anchors and being configured to be attached to the at least two leaflets of the native heart valve of the patient when the at least two leaflets are held by the implantable device in the relatively fixed position;

wherein the connector includes a wedge and a locking nut;

the connector having angled engagement surfaces that are configured to engage the at least two leaflets of the native valve and having a base surface with a locking aperture;

a first suture attached to the first anchor;

a second suture attached to the second anchor;

wherein the first suture and the second suture are received by the angled engagement surfaces, exit the wedge through the base surface and extend through an internal passage of the locking nut;

wherein the locking nut is configured to be at least partially received in the locking aperture;

wherein the locking nut is configured to capture the first suture and the second suture between the locking nut and the wedge; and

the implantable device being configured to be detached from the at least two leaflets and removed from the patient with the connector remaining attached to the at least two leaflets.

2 . The heart valve repair system of claim 1 , wherein the implantable device is configured both to allow the implantable device to remain attached to the native heart valve after the connector is attached to the native heart valve and to allow the implantable device to be removed from the native heart valve after the connector is attached to the native heart valve.

3 . The heart valve repair system of claim 2 , wherein the implantable device includes a spacer element.

4 . The heart valve repair system of claim 1 , wherein the implantable device includes a plurality of paddles that each comprise an inner paddle portion and an outer paddle portion.

5 . The heart valve repair system of claim 1 , wherein the implantable device and the connector are configured to close a gap in the native heart valve of the patient when the valve repair system is attached to the native heart valve.

6 . The heart valve repair system of claim 1 , wherein the first anchor comprises a pledget.

7 . The heart valve repair system of claim 1 , wherein the implantable device includes a first anchor configured to embed into a first valve leaflet and a second anchor configured to embed into a second valve leaflet.

8 . The heart valve repair system of claim 1 , wherein the locking nut is configured to be threaded into the locking aperture until the first suture line and the second suture line are sandwiched between the locking nut and an interior surface of the wedge.

9 . The heart valve repair system of claim 1 , wherein the locking nut is sized such that the locking nut and the base surface form a step.

10 . The heart valve repair system of claim 1 , wherein the locking nut is sized such that the locking nut is spaced apart from the at least two leaflets of the native heart valve.

11 . A valve repair system comprising:

an implantable device comprising:

first and second paddles that are movable between an open position and a closed position;

first and second tissue-gripping elements associated with the first and second paddles, respectively, each of the first and second tissue-gripping elements being configured to attach to a respective leaflet of a native heart valve of a patient;

a connector configured to be implanted in first and second leaflets of the native heart valve of the patient when the implantable device is gripped to the first and second leaflets and to allow for the implantable device to be removed when the connector is implanted in the first and second leaflets, the connector comprising:

a first anchor configured to engage a first valve leaflet of the native heart valve of the patient;

a second anchor configured to engage a second valve leaflet of the native heart valve of the patient;

a first suture attached to the first anchor;

a second suture attached to the second anchor;

wherein the first suture and the second suture extend between the first anchor and the second anchor;

a wedge having angled engagement surfaces that are configured to engage the first valve leaflet and the second valve leaflet between the first anchor and the second anchor and having a base surface with a locking aperture;

a locking nut at least partially received in the locking aperture;

wherein the first suture and the second suture are received by the angled engagement surfaces, exit the wedge through the base surface, and extend through an internal passage of the locking nut; and

wherein the locking nut is configured to capture the first suture and the second suture between the locking nut and the wedge.

12 . The valve repair system of claim 11 , wherein the implantable device is configured both to allow the implantable device to remain attached to the native heart valve after the connector is attached to the native heart valve and to allow the implantable device to be removed from the native heart valve after the connector is attached to the native heart valve.

13 . The valve repair system of claim 11 , wherein each of the first and second paddles comprise an inner paddle portion and an outer paddle portion.

14 . The valve repair system of claim 11 , wherein the connector is configured to keep a gap in the native heart valve of the patient closed after the implantable device is removed.

15 . The valve repair system of claim 11 , wherein the first anchor comprises a pledget.

16 . The valve repair system of claim 11 , wherein the first anchor is configured to embed into the first valve leaflet and the second anchor is configured to embed into the second valve leaflet.

17 . The valve repair system of claim 11 , wherein the locking nut is configured to be threaded into the lacking aperture until the first suture line and the second suture line are sandwiched between the locking nut and an interior surface of the wedge.

18 . The valve repair system of claim 11 , wherein the locking nut is sized such that the locking nut and the base surface form a step.

19 . The valve repair system of claim 11 , wherein the locking nut is sized such that the locking nut is spaced apart from the at least two leaflets of the native heart valve.

20 . A heart valve repair system comprising:

an implantable device configured to attach to at least two leaflets of a native heart valve of a patient and hold the at least two leaflets in a relatively fixed position; and

a connector that is separate from the implantable device, the connector including first and second tissue anchors and being configured to be attached to the at least two leaflets of the native heart valve of the patient when the at least two leaflets are held by the implantable device in the relatively fixed position;

wherein the connector includes a wedge and a lock;

the connector having angled engagement surfaces that are configured to engage the at least two leaflets of the native valve and having a base surface;

a first suture attached to the first anchor;

a second suture attached to the second anchor;

wherein the first suture and the second suture are received by the angled engagement surfaces, exit the wedge through the base surface and extend through an internal passage of the lock; and

the implantable device being configured to be detached from the at least two leaflets and removed from the patient with the connector remaining attached to the at least two leaflets.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2022
From: NIA, NIMA V.; CAO, HENGCHU; SU, BINGQUAN; DOMINICK, DOUGLAS THOMAS; TRIPATHY, SAKYASINGH
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 060876/0089 →
Continuity (3)
Continuation PCTUS2020027789 · Apr 10, 2020
Provisional Application 62836839 · Apr 22, 2019
Related Publication 20220039954A1 · Feb 10, 2022
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