IP Library › Granted Patent US 12,636,617
Granted Patent B2
US 12,636,617 · App. 18/493,880 · Granted May 26, 2026

Compact spiral-wound filter elements, modules and systems

Inventor: Jonathan Steen (Worcester, MA)
Assignee: EMD Millipore Corporation
B01D63/12B01D61/025B01D61/145B01D63/103B01D63/107C02F1/44C02F1/441C02F1/442D06C15/02B01D61/147B01D67/0086B01D71/68B01D2313/14B01D2313/143B01D2313/146B01D2315/10B01D2315/16B01D2317/02C02F1/444
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Quick Facts
Patent No.
US 12,636,617
App. No.
18/493,880
Granted
May 26, 2026
Kind
B2
Abstract

The present invention provides compact spiral-wound filter elements having cassette-like performance. The invention further provides filtration systems (e.g., TFF systems) and processes (e.g., SPTFF processes) employing compact spiral-wound filter elements having cassette-like performance.

Claims (15)

1 . A filter system, comprising: two or more filter modules, each of the two or more filter modules comprising: a housing, a spiral-wound filter element comprised of a spiral-wound membrane having an interior, said spiral-wound membrane wrapped around and attached to a perforated core having an interior, with the interior of a single leaf spiral-wound membrane in fluid communication with the interior of the perforated core, said interior of the single leaf spiral-wound membrane and interior of the perforated core forming a permeate channel, and a feed stream inlet located on the housing external to the spiral-wound membrane, wherein said two or more modules are in fluid communication in series such that retentate of a first filter module becomes the feed stream of a second filter module or the permeate of the first filter module becomes the feed stream of the second filter module and the feed channel flow cross section changes between at least two successive modules and wherein the outermost feed channel of the spiral-wound filter element is blocked.

2 . The filter system of claim 1 , wherein feed channel flow cross section successively decreases.

3 . The filter system of claim 2 , wherein the feed channel height remains the same.

4 . The filter system of claim 1 , said filter system further comprising a feed screen.

5 . The filter system of claim 4 , wherein said feed screen is a high turbulence-promoting feed screen.

6 . The filter system of claim 1 , said filter system further comprising a permeate screen.

7 . The filter system of claim 1 , wherein the retentate of the first filter module becomes the feed of the second filter module.

8 . The filter system of claim 1 , wherein the permeate of the first filter module becomes the feed of the second filter module.

9 . The filter system of claim 1 , wherein said filter system is a tangential flow filter (TFF) system.

10 . The filter system of claim 1 , wherein said filter system is a single-pass tangential filter (SPTFF) system.

11 . The filter system of claim 1 , wherein said permeate exits the filter module from the core.

12 . The filter system of claim 1 , comprising an ultrafiltration membrane, a microfiltration membrane, a reverse-osmosis membrane or a nanofiltration membrane.

13 . The filter system of claim 1 , further comprising a reservoir for diafiltration solution and a conduit for delivering diafiltration to a feed reservoir.

14 . A process for filtering a liquid, comprising: passing a liquid feed through filter system of claim 1 , separating the liquid feed into permeate and retentate in the filter system; and recovering the permeate and at least a portion of the retentate from the filter system.

15 . The filter system of claim 1 , wherein said spiral-wound membrane is a single leaf spiral-wound membrane.

Continuity (5)
Continuation 17656285 · Mar 24, 2022
Continuation 16428189 · May 31, 2019
Division 14750838 · Jun 25, 2015
Provisional Application 62017084 · Jun 25, 2014
Related Publication 20240050900A1 · Feb 15, 2024
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