IP Library Granted Patent US 12,643,105
Granted Patent B2
US 12,643,105 · App. 18/065,007 · Granted Jun 2, 2026

Method and device for collecting and analysing airborne particles

Inventors: Guillaume Blaire (Grenoble Cedex, FR); Manuel Alessio (Grenoble Cedex, FR); Mélissa Baque (Grenoble Cedex, FR); Jean-Maxime Roux (Grenoble Cedex, FR)
Assignee: Commissariat à l'Energie Atomique et aux Energies Alternatives
B01L3/502761B01L7/52C12Q1/6844G01N1/2202B01L2200/0652B01L2200/16B01L2400/0677C12Q1/6806G01N2001/222
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Quick Facts
Patent No.
US 12,643,105
App. No.
18/065,007
Granted
Jun 2, 2026
Kind
B2
Abstract

A method for collecting and analysing airborne particles, including a step of eluting particles precipitated on a collecting surface, a step of analysing the airborne particles collected in the reaction chamber, the eluting step being carried out by heating a first reservoir containing the elution liquid to a first temperature value, the analysing step being carried out by heating the reaction chamber to a second temperature value higher than the first temperature value, so as to: activate a detection reaction in the reaction chamber, isolate the reaction chamber during the detection reaction, initiate a device for sealing the reaction chamber, a step of sealing the reaction chamber.

Claims (15)

1 . A method for collecting and analysing airborne particles, comprising:

precipitating particles from air on a collecting surface;

injecting a first reservoir with elution liquid to store the elution liquid in the first reservoir under pressure resulting from the injecting, an outlet of the first reservoir being blocked by a first meltable compound;

heating the first reservoir containing the elution liquid to a first temperature value to melt the first meltable compound;

conveying, via the pressure of the first reservoir, the elution liquid through an elution fluidic circuit to the collecting surface;

conveying the elution liquid along with the precipitated particles through the elution fluidic circuit to a reaction chamber of an analysis module;

heating the reaction chamber to a second temperature value higher than the first temperature value, so as to activate a detection reaction in said reaction chamber;

isolating said reaction chamber during the detection reaction by melting a second meltable compound and sealing said reaction chamber by setting the second meltable compound when the temperature drops to a third temperature value lower than said second temperature value; and

analyzing the airborne particles collected in the reaction chamber.

2 . The method according to claim 1 , further comprising controlling the detection reaction by injecting a second elution liquid into at least one control chamber identical to said reaction chamber.

3 . The method according to claim 2 , wherein each elution liquid contains reagents.

4 . The method according to claim 1 , wherein the detection reaction is a biomolecular-amplification reaction.

5 . The method according to claim 1 , wherein isolating the reaction chamber includes closing via a deformable membrane, a first isolation valve arranged in the elution fluidic circuit.

6 . The method according to claim 5 , wherein sealing the reaction chamber includes releasing the second meltable compound into the elution fluidic circuit.

7 . The method according to claim 5 , wherein sealing the reaction chamber includes releasing the second meltable compound so that the second meltable compound deposits on the deformable membrane of the first isolation valve.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 13, 2022
From: BLAIRE, GUILLAUME; ALESSIO, MANUEL; BAQUE, MÉLISSA; ROUX, JEAN-MAXIME
To: COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Reel/Frame 062065/0101 →
Priority Claims (1)
FR 21 13752 · Dec 17, 2021 · national
Continuity (1)
Related Publication 20230191410A1 · Jun 22, 2023
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