Physiological signal monitoring system for fast assembly
An implantation device for prompt subcutaneous implantation of a sensor to measure a physiological signal of an analyte in a biofluid of a living body is disclosed. The implantation device includes a housing, an implantation module, a detachable module and a bottom cover. The housing has a bottom opening. The implantation module includes an implanting device and a needle extracting device. The detachable module includes the sensor detachably engaged with the implantation module; and a base configured to mount the sensor thereon. The bottom cover is detachably coupled to the bottom opening so that the housing and the bottom cover together form an accommodating space. The implantation module and the detachable module are accommodated in the accommodating space. The bottom cover has an operating portion configured to bear a force, and a supporting portion is formed on the opposite end of the operating portion.
1 . An implantation device for prompt subcutaneous implantation of a sensor to measure a physiological signal of an analyte in a biofluid of a living body having a skin surface, comprising:
a housing having a bottom opening and a lining piece disposed therein, the lining piece having an actuating portion protruding therefrom;
an implantation module including;
a main body, connected to the lining piece, having a slide groove extending along an axial direction, a pair of recessed portions, and a stopping portion adjacent to the pair of recessed portions;
a main cover connected to the main body, defining a displacement space together with the main body, and including a constraint element disposed along the axial direction;
a needle implanting seat movably disposed in the displacement space extendable along the axial direction, and including:
a limiting groove extending parallel to the axial direction,
a limiting element disposed on an inner cylindrical member and configured to be restricted by the limiting groove from radial deflection for keeping a needle extracting seat at a constant location relative to the needle implanting seat, and
a pair of buckle portions having elasticity and configured for causing bias relative to the axial direction, respectively disposed on an outer cylindrical member and detachably sitting on the stopping portion;
a first elastic element disposed between the needle implanting seat and the lining piece in a first pre-compressed manner;
the needle extracting seat slidably installed inside the needle implanting seat along the axial direction; and
a second elastic element disposed between the needle implanting seat and the needle extracting seat in a second pre-compressed manner; and
a detachable module including the sensor detachably engaged with the implantation module, and
wherein:
when the implantation module is in a first operating status before the detachable module is attached on the skin surface, the constraint element of the main cover and the limiting groove of the needle implanting seat are kept in a constraint state,
when the implantation module is in a second operating status that the detachable module is in a process of being attached on the skin surface, the first elastic element in the first pre-compressed manner is released to a released manner by an external force exerting on the housing through the actuating portion to bias the pair of buckle portions to release the stopping portion so that the constraint element and the limiting groove are not in the constraint state, and
when the detachable module has been attached on the skin surface, the needle extracting seat is withdrawn upward so as to release the second elastic element from being in the second pre-compressed manner.
2 . The implantation device according to claim 1 , further comprising:
a bottom cover detachably coupled to the bottom opening so that the housing and the bottom cover together form an accommodating space.
3 . The implantation device according to claim 2 , further comprising:
a desiccation indicator disposed at a location visible through a transparent or translucent portion of the housing and configured to provide a visual indication of a dryness within the accommodating space.
4 . The implantation device according to claim 2 , wherein the detachable module further includes:
an adhesive pad disposed on a base of the detachable module;
a release layer releasably attached to the adhesive pad; and
a tearing element connected to the release layer and attached to a chassis portion of the bottom cover, wherein the tearing element is configured to tear away the release layer from the adhesive pad when the bottom cover is separated from the bottom opening by a user.
5 . The implantation device according to claim 2 , wherein:
the bottom cover has a side wall adjacent to the bottom opening,
the bottom cover has an operating portion protruding from the side wall to bear a force in a direction away from the housing, wherein the operating portion enables a supporting portion to be formed on an opposite end from the operating portion,
a distance between the operating portion and the supporting portion and the force form an operating moment allowing a user to cause a partial side detachment between the bottom cover and the housing,
after the bottom cover is separated from the bottom opening by the user, the housing is operated to cause the implantation module to release an action force to cause the detachable module to be detached from the implantation module and to subcutaneously implant a portion of the sensor to measure the physiological signal.
6 . The implantation device according to claim 5 , wherein the operating portion is a convex portion.
7 . The implantation device according to claim 5 , wherein the force is in a range of 0.2 kgf and 10 kgf.
8 . The implantation device according to claim 5 , wherein the distance between the operating portion and the supporting portion is in a range of 15 millimeters to 100 millimeters.
9 . The implantation device according to claim 5 , wherein:
the operating portion is oriented in a first plane;
the bottom cover has a positioning piece that is oriented in a second plane that is substantially perpendicular to the first plane;
the bottom opening has a matching portion oriented in the second plane and configured to abut and align with the positioning piece when the bottom cover and the housing are engaged; and
the operating portion is configured to cause a partial side detachment between the bottom cover and the housing, taking advantage of a stress concentration status using the force, and continually applying the force on the operating portion toward a direction away from the housing to enlarge the partial side detachment.
10 . The implantation device according to claim 9 , wherein the bottom cover defines a reference point, and wherein an angle formed by a first imaginary line extending from the reference point to the positioning piece and a second imaginary line extending from the reference point to the operating portion is in a range of 5 degrees and 180 degrees.
11 . The implantation device according to claim 9 , wherein:
the partial side detachment is caused by overcoming a resistance force generated due to a combination between the bottom cover and the housing; and
during the partial side detachment, the resistance force moves progressively from a first abutment location near the operating portion to a second abutment location farther from the operating portion, wherein the distance in the operating moment increases progressively from a first distance to a second distance greater than the first distance, thereby reducing the force required to maintain the operating moment during the partial side detachment.
12 . The implantation device according to claim 2 , wherein:
the bottom opening has a first convex ring disposed along an edge of the bottom opening and a first annular groove disposed near the edge of the bottom opening to abut the first convex ring;
the bottom cover has a second convex ring disposed along an edge of the bottom cover and a second annular groove disposed near the edge of the bottom cover to abut the second convex ring;
the first convex ring is fitted into the second annular groove, and the second convex ring is fitted into the first annular groove;
the detachable module further includes a base configured to mount the sensor thereon and having an adhesive pad disposed thereon;
the housing further includes a protective ring sleeved on a bottom portion of the housing and having a lateral opening, wherein the base and the adhesive pad are disposed on an inner side of a bottom edge of the protective ring such that when the bottom edge of the protective ring abuts against the skin surface, wherein the adhesive pad does not contact the skin surface and is visible through the lateral opening before implantation of the sensor;
the implantation module and the detachable module are accommodated in the accommodating space.
13 . A physiological signal monitoring system for fast assembly and measuring a physiological signal of an analyte in a living body having a skin surface, comprising:
an implantation device including:
a housing having a bottom opening and a lining piece disposed therein, the lining piece having an actuating portion protruding therefrom;
an implantation module including:
a main body, connected to the lining piece, having a slide groove extending along an axial direction, a pair of recessed portions, and a stopping portion adjacent to the pair of recessed portions;
a main cover connected to the main body, defining a displacement space together with the main body, and including a constraint element disposed along the axial direction;
a needle implanting seat movably disposed in the displacement space extendable along the axial direction, and including:
a limiting groove extending parallel to the axial direction,
a limiting element disposed on an inner cylindrical member and configured to be restricted by the limiting groove from radial deflection for keeping a needle extracting seat at a constant location relative to the needle implanting seat, and
a pair of buckle portions having elasticity and configured for causing bias relative to the axial direction, respectively disposed on an outer cylindrical member and detachably sitting on the stopping portion;
a first elastic element disposed between the needle implanting seat and the lining piece in a first pre-compressed manner;
the needle extracting seat slidably installed inside the needle implanting seat along the axial direction; and
a second elastic element disposed between the needle implanting seat and the needle extracting seat in a second pre-compressed manner; and
a detachable module including:
a sensor configured to be detachably partially implanted into the living body; and
a base disposing the sensor thereon after the sensor is partially implanted into the living body; and
a bottom cover detachably coupled to the bottom opening so that the housing and the bottom cover together form an accommodating space; and
a transmitter coupled with the base after the sensor is partially implanted into the living body for transmitting the physiological signal that is measured by the sensor,
wherein:
when the implantation module is in a first operating status before the detachable module is attached on the skin surface, the constraint element of the main cover and the limiting groove of the needle implanting seat are kept in a constraint state,
when the implantation module is in a second operating status that the detachable module is in a process of being attached on the skin surface, the first elastic element in the first pre-compressed manner is released to a released manner by an external force exerting on the housing through the actuating portion to bias the pair of buckle portions to release the stopping portion so that the constraint element and the limiting groove are not in the constraint state, and
when the detachable module has been attached on the skin surface, the needle extracting seat is withdrawn upward so as to release the second elastic element from being in the second pre-compressed manner.
14 . The physiological signal monitoring system according to claim 13 , wherein:
the bottom cover has a side wall and an operating portion protruding therefrom to bear a force in a direction away from the housing,
the operating portion enables a supporting portion to be formed on an opposite end from the operating portion, and
the operating portion is a convex portion having a length of no less than 1 millimeter.
15 . The physiological signal monitoring system according to claim 13 , wherein the bottom opening and the bottom cover have a first joint portion and a second joint portion respectively, the first joint portion is a convex ring disposed along an edge of the bottom opening, the second joint portion is an annular groove disposed along an edge of the bottom cover, and the convex ring is fitted into the annular groove.
16 . An implantation device for prompt subcutaneous implantation of a sensor for measuring a physiological signal of a living body having a skin surface, comprising:
a housing having a bottom opening and a lining piece disposed therein, the lining piece having an actuating portion protruding therefrom;
an implantation module, disposed in the housing, including:
a main body, connected to the lining piece, having a slide groove extending along an axial direction, a pair of recessed portions, and a stopping portion adjacent to the pair of recessed portions;
a main cover connected to the main body, defining a displacement space together with the main body, and including a constraint element disposed along the axial direction;
a needle implanting seat movably disposed in the displacement space extendable along the axial direction, and including:
a limiting groove extending parallel to the axial direction,
a limiting element disposed on an inner cylindrical member and configured to be restricted by the limiting groove from radial deflection for keeping a needle extracting seat at a constant location relative to the needle implanting seat, and
a pair of buckle portions having elasticity and configured for causing bias relative to the axial direction, respectively disposed on an outer cylindrical member and detachably sitting on the stopping portion;
a first elastic element disposed between the needle implanting seat and the lining piece in a first pre-compressed manner;
the needle extracting seat slidably installed inside the needle implanting seat along the axial direction; and
a second elastic element disposed between the needle implanting seat and the needle extracting seat in a second pre-compressed manner; and
a sensor module detachably disposed in the implantation module to be attached on the skin surface and including a sensor and a base configured to mount the sensor thereon, wherein the base has an adhesive pad disposed thereon,
wherein:
when the implantation module is in a first operating status before the sensor module is attached on the skin surface, the constraint element of the main cover and the limiting groove of the needle implanting seat are kept in a constraint state,
when the implantation module is in a second operating status that the sensor module is in a process of being attached on the skin surface, the first elastic element in the first pre-compressed manner is released to a released manner by an external force exerting on the housing through the actuating portion to bias the pair of buckle portions to release the stopping portion so that the constraint element and the limiting groove are not in the constraint state, and
when the sensor module has been attached on the skin surface, the needle extracting seat is withdrawn upward so as to release the second elastic element from being in the second pre-compressed manner.
17 . The implantation device according to claim 16 , wherein:
the implantation module further includes a bottom cover detachably coupled with the bottom opening so that the housing and the bottom cover together form an accommodating space,
the bottom cover has a side wall adjacent to the bottom opening,
the bottom cover has an operating portion protruding from the side wall to bear a force in a direction away from the housing, and enable a supporting portion to be formed on an opposite end from the operating portion,
a distance between the operating portion and the supporting portion and the force form an operating moment,
the operating portion is configured to initiate a partial side detachment between the bottom cover and the housing, taking advantage of a stress concentration status using the force, to cause the partial side detachment between the bottom cover and the housing,
the operating portion is configured to continually bear the force in a direction away from the housing to enlarge the partial side detachment, which causes the bottom cover to be separated from the bottom opening,
the housing is put under an operating condition to cause the sensor module to be attached on the skin surface for measuring the physiological signal,
the bottom opening and the bottom cover have a first joint portion and a second joint portion,
the housing further includes a protective ring sleeved on a bottom portion of the housing and having a lateral opening recessed into a lateral surface of the protective ring, and
the implantation module and the sensor module are accommodated in the accommodating space.
18 . The implantation device according to claim 17 , wherein the accommodating space is an air-tight space.
19 . The implantation device according to claim 17 , wherein:
the bottom cover further includes:
an inner side surface and a pair of blocking portions protruding from the inner side surface;
the main body further includes:
a pair of fixing members, wherein a fixing member is slidably installed in the slide groove and has a pushing portion corresponding to a respective one of the pair of blocking portions;
the supporting portion opposite to the pushing portion;
a first hook disposed between the pushing portion and the supporting portion; and
a guiding portion disposed between the pushing portion and the supporting portion, and having a guide slanting surface;
the needle implanting seat further includes:
a flat plate portion;
the inner cylindrical member connected to the flat plate portion and configured for intersecting therewith; and
the outer cylindrical member connected to the flat plate portion, configured for intersecting therewith, and surrounding the inner cylindrical member;
the main cover is disposed between the lining piece and the needle implanting seat, and
the first elastic element is disposed between the needle implanting seat and the main cover in the first pre-compressed manner.
20 . The implantation device according to claim 17 , wherein the base and the adhesive pad of the sensor module are disposed on an inner side of a bottom edge of the protective ring.