IP Library › Granted Patent US 12,653,539
Granted Patent B2
US 12,653,539 · App. 18/490,986 · Granted Jun 16, 2026

Left atrial appendage closure device

Inventors: Jan-Hung Chen (St. Paul, MN); Harishankar Natesan (Shoreview, MN); Thyna M. Chau (Woodbury, MN)
Assignee: Boston Scientific Scimed, Inc.
A61B17/12172A61B17/12031A61B17/12122A61B2017/1205
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Quick Facts
Patent No.
US 12,653,539
App. No.
18/490,986
Granted
Jun 16, 2026
Kind
B2
Abstract

A left atrial appendage closure device may include an expandable framework having a plurality of struts joined at a proximal and distal hub. When the framework is fully constrained in a first position, a first segment of struts extends distally from the distal hub parallel to a central longitudinal axis to a first bend and a second segment of struts extends from the first bend proximally. A first amount of the framework is unconstrained in a second position, where the first segment extends distally from the distal hub parallel to the central longitudinal axis to the first bend, the second segment extends from the first bend proximally and radially outward to a second bend, a third segment of struts extends from the second bend proximally and radially inward to a third bend, and a fourth segment of struts extends from the third bend proximally to within the delivery sheath.

Claims (46)

1 . A medical implant, comprising:

an expandable framework having a plurality of struts disposed about a central longitudinal axis, the plurality of struts being joined at a proximal hub and a distal hub;

wherein the plurality of struts of the expandable framework are formed from a unitary tubular member:

wherein the expandable framework includes a proximal shoulder region extending from the proximal hub to a proximal shoulder region end point, and wherein the expandable framework includes a distal shoulder region extending from the distal hub to a distal shoulder region end point; and

wherein the portion of the expandable framework extending between the proximal shoulder region end point and the distal shoulder region end point is substantially parallel to the central longitudinal axis; and

wherein the plurality of struts extending between the proximal hub and the distal hub define an interior volume of the expandable framework, and wherein the proximal hub is located outside the interior volume of the expandable framework and the distal hub is located within the interior volume of the expandable framework;

wherein in a fully unconstrained configuration of the expandable framework, a first segment of the plurality of struts extends distally from the distal hub to a first bend, and a second segment of the plurality of struts extends from the first bend distally and radially outward to a second bend.

2 . The medical implant of claim 1 , wherein the proximal shoulder region includes a first grouping of cells adjacent to the proximal hub and defining a first row, and wherein a first cell in the first row of cells includes a first strut segment and a second strut segment joined at a first distal node.

3 . The medical implant of claim 2 , wherein the first row of cells extends circumferentially around the central longitudinal axis of the expandable framework.

4 . The medical implant of claim 3 , wherein the expandable framework further includes a second grouping of cells defining a second row adjacent to the first row, and wherein a second cell in the second row of cells includes a third strut segment and a fourth strut segment joined at a second distal node.

5 . The medical device of claim 4 , wherein the width of at least one cell of the second grouping of cells is different than the width of the cells defining the first grouping of cells.

6 . The medical device of claim 5 , wherein the width of at least one cell of the second grouping of cells is wider than the width of the cells defining the first grouping of cells.

7 . The medical implant of claim 1 , further comprising a membrane disposed along an outer surface of the expandable framework.

8 . The medical implant of claim 7 , wherein the membrane extends along the outer surface of the expandable framework from the proximal hub to a membrane end point, and wherein the membrane end point is positioned along the portion of the expandable framework that is substantially parallel to the central longitudinal axis.

9 . The medical implant of claim 8 , wherein the membrane end point is positioned at a second node of the second grouping of cells.

10 . The medical implant of claim 1 , wherein the expandable framework further includes a plurality of fixation members disposed thereon.

11 . The medical implant of claim 10 , wherein the plurality of fixation members are formed from the unitary tubular member.

12 . The medical implant of claim 11 , wherein at least a portion of the plurality of fixation members extend through an aperture formed in the membrane.

13 . The medical implant of claim 1 , wherein the plurality of struts extending between the proximal hub and the distal hub define an interior volume of the expandable framework, and wherein the proximal hub is located outside the interior volume of the expandable framework and the distal hub is located within the interior volume of the expandable framework, and wherein when in the expanded configuration, the distal hub is positioned proximal of a distalmost extent of the expandable framework.

14 . The medical implant of claim 1 , wherein the expandable framework is configured to shift between a first unexpanded configuration and an expanded configuration, and wherein when in the expanded configuration, the distal hub is positioned proximal of a distalmost extent of the expandable framework.

15 . An occlusive implant, comprising:

an expandable framework having a plurality of struts disposed about a central longitudinal axis, the plurality of struts being joined at a proximal hub and a distal hub;

wherein the plurality of struts of the expandable framework are formed from a unitary tubular member;

wherein the expandable framework includes a proximal shoulder region extending from the proximal hub to a proximal shoulder region end point; and

wherein the expandable framework includes a distal shoulder region extending from the distal hub to a distal shoulder region end point; and

wherein the portion of the expandable framework extending between the proximal shoulder region end point and the distal shoulder region end point is substantially parallel to the central longitudinal axis; and

wherein the plurality of struts extending between the proximal hub and the distal hub define an interior volume of the expandable framework, and wherein the proximal hub is located outside the interior volume of the expandable framework and the distal hub is located within the interior volume of the expandable framework;

wherein when the expandable framework is disposed within a delivery sheath in a fully constrained configuration, a first segment of the plurality of struts extends distally from the distal hub to a first bend, and a second segment of the plurality of struts extends from the first bend proximally;

wherein in a fully unconstrained configuration of the expandable framework, the first segment of the plurality of struts extends distally from the distal hub to the first bend, and the second segment of the plurality of struts extends from the first bend distally and radially outward to a second bend;

a membrane disposed along an outer surface of the expandable framework, wherein the membrane extends along the outer surface of the expandable framework from the proximal hub to a membrane end point; and

a plurality of fixation members disposed along the expandable framework.

16 . The occlusive implant of claim 15 , wherein the membrane end point is positioned along the portion of the expandable framework that is substantially parallel to the central longitudinal axis.

17 . The occlusive implant of claim 16 , wherein the expandable framework and the plurality of fixation members are formed from a unitary tubular member.

18 . The occlusive implant of claim 17 , wherein at least a portion of the plurality of fixation members extend through an aperture formed in the membrane.

19 . The occlusive implant of claim 15 , wherein the plurality of struts extending between the proximal hub and the distal hub define an interior volume of the expandable framework, and wherein the proximal hub is located outside the interior volume of the expandable framework and the distal hub is located within the interior volume of the expandable framework.

20 . A method for occluding a left atrial appendage of a patient, the method comprising:

positioning an occlusive implant adjacent the left atrial appendage, the occlusive implant including:

an expandable framework having a plurality of struts disposed about a central longitudinal axis, the plurality of struts being joined at a proximal hub and a distal hub;

wherein the plurality of struts of the expandable framework are formed from a unitary tubular member;

wherein the expandable framework includes a proximal shoulder region extending from the proximal hub to a proximal shoulder region end point; and

wherein the expandable framework includes a distal shoulder region extending from the distal hub to a distal shoulder region end point, and wherein the portion of the expandable framework extending between the proximal shoulder region end point and the distal shoulder region end point is substantially parallel to the central longitudinal axis; and

wherein the plurality of struts extending between the proximal hub and the distal hub define an interior volume of the expandable framework, and wherein the proximal hub is located outside the interior volume of the expandable framework and the distal hub is located within the interior volume of the expandable framework;

wherein in a fully unconstrained configuration of the expandable framework, a first segment of the plurality of struts extends distally from the distal hub to a first bend, and a second segment of the plurality of struts extends from the first bend distally and radially outward to a second bend;

a membrane disposed along an outer surface of the expandable framework, wherein the membrane extends along the outer surface of the expandable framework from the proximal hub to a membrane end point; and

a plurality of fixation members disposed along the expandable framework; and

expanding the occlusive implant within the left atrial appendage such that the membrane extends across an ostium of the left atrial appendage.

Continuity (3)
Continuation 17857513 · Jul 5, 2022
Provisional Application 63219696 · Jul 8, 2021
Related Publication 20240041469A1 · Feb 8, 2024
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