IP Library Granted Patent US 12,653,849
Granted Patent B2
US 12,653,849 · App. 18/493,979 · Granted Jun 16, 2026

Materials and methods for inhibiting a viral infection, including a coronavirus infection

Inventors: Nicholas T. Monsul (Sarasota, FL); Eva A. Berkes (Sarasota, FL); Frederick T. Boehm (Sarasota, FL); Yu-Hsien Liao (Sarasota, FL)
Assignee: QUORUM INNOVATIONS, INC.
A61K35/747A61K38/164A61K45/06A61P31/14C07K14/335C12N1/205C12R2001/225
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Quick Facts
Patent No.
US 12,653,849
App. No.
18/493,979
Granted
Jun 16, 2026
Kind
B2
Abstract

The subject invention provides compositions and methods for inhibiting viral infections. Preferred embodiments of the invention provide pharmaceutical compositions, and the methods of using the same, comprising a strain of Lactobacillus fermentum bacterium, or bioactive extracts thereof.

Claims (13)

1 . A self-decontaminating surface having antiviral properties wherein said surface comprises a composition comprising an isolated bioactive Lactobacillus fermentum bacterial strain grown as biofilm; wherein the Lactobacillus fermentum strain is Lactobacillus fermentum Qi6 having Accession No. PTA-122195, and wherein the surface is cloth, textile, metal, ceramic, or wood.

2 . The self-decontaminating surface of claim 1 , wherein the virus is an RNA virus.

3 . The self-decontaminating surface of claim 2 , wherein the virus is a coronavirus.

4 . The self-decontaminating surface of claim 2 , wherein the coronavirus is SARS-CoV-2.

5 . The self-decontaminating surface of claim 2 , wherein the coronavirus is SARS-COV.

6 . The self-decontaminating surface of claim 2 , wherein the coronavirus is MERS-COV.

7 . The self-decontaminating surface of claim 1 , wherein the surface is cloth.

8 . The self-decontaminating surface of claim 1 , wherein the surface is textile.

9 . The self-decontaminating surface of claim 1 , wherein the surface is metal.

10 . The self-decontaminating surface of claim 1 , wherein the surface is ceramic.

11 . The self-decontaminating surface of claim 1 , wherein the surface is wood.

12 . The self-decontaminating surface of claim 1 , wherein the bacterial strain has been grown as a biofilm in culture, and then applied to the surface.

13 . The self-decontaminating surface of claim 1 , wherein the biofilm on the surface does not comprise any living cells.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 18, 2025
From: QUORUM INNOVATIONS, LLC
To: QUORUM INNOVATIONS, INC.
Reel/Frame 072048/0175 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2023
From: MONSUL, NICHOLAS T.; BERKES, EVA A; BOEHM, FREDERICK T.; LIAO, YU-HSIEN
To: QUORUM INNOVATIONS, LLC
Reel/Frame 065745/0860 →
Continuity (3)
Continuation 17418440
Provisional Application 63035733 · Jun 6, 2020
Related Publication 20240075083A1 · Mar 7, 2024
References Cited (12)
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Subhadra, B., et al., “Draft Whole-Genome Sequence of Lactobacillus fermentum LfQi6, Derived from the Human Microbiome.” Genome Announcements, 2015, 3(3): e00423-15, pp. 1-2. [cited by applicant]