IP Library Granted Patent US 12,659,893
Granted Patent B2
US 12,659,893 · App. 18/557,914 · Granted Jun 16, 2026

Technique for obtaining and processing a measurement of a biosignal

Inventors: Brian Murphy (Greystones, IE); Yannick Tremblay (Dunmurry, GB); Hugh Nolan (Dublin, IE); Matthew Shaw (Bushmills, GB)
Assignee: CUMULUS NEUROSCIENCE LTD
H04W56/001A61B5/002A61B5/6814H04W84/12
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Quick Facts
Patent No.
US 12,659,893
App. No.
18/557,914
Granted
Jun 16, 2026
Kind
B2
Abstract

A head-wearable sensor arrangement for obtaining a measurement of biosignal of a user is provided. The present disclosure also relates to a stimulus-providing wireless mobile device and a computing system. The head-wearable sensor arrangement may send time-stamped medical data comprising a representation of the measurement to the wireless mobile device time-synchronized with the arrangement. The wireless mobile device may send the time-stamped medical data to a computing system. The computing system may process the time-stamped medical data to determine an indicator of health, well-being or performance of the user. The processing may involve decomposing the measurement and using residuals of an autoregressive model or a robust aggregation method on the decomposed measurement.

Claims (63)

1 . A wireless head-wearable sensor arrangement for sending medical data to a wireless mobile device, the wireless head-wearable sensor arrangement comprising:

at least one sensor configured to generate at least one measurement of a biosignal of a user wearing the wireless head-wearable sensor arrangement;

a first wireless interface;

a first clock; and

a first processor configured to:

perform a time-synchronization procedure to synchronize the first clock with a second clock of the wireless mobile device or to instruct synchronization of the second clock of the wireless mobile device with the first clock;

after having performed the time-synchronization procedure, obtain, from the at least one sensor, the at least one measurement of the biosignal of the user wearing the wireless head-wearable sensor arrangement, allocate at least one time-stamp to the obtained at least one measurement, and send the medical data via the first wireless interface to the wireless mobile device, the medical data comprising a representation of the at least one measurement and the at least one time-stamp allocated to the at least one measurement, wherein the first processor is configured to perform the time-synchronization procedure by:

sending a time information request message to the wireless mobile device via the first wireless interface, the time information request message comprising a first time-stamp of a time of sending the time information request message; and

receiving a time information response message from the wireless mobile device via the first wireless interface, the time information response message comprising synchronization information,

wherein the first processor is configured to synchronize the first clock by adjusting the first clock based at least on the synchronization information,

wherein the first processor is configured to, after having adjusted the first clock, send a configuration message to the wireless mobile device via the first wireless interface, the configuration message comprising at least one of a second time-stamp of a time of sending the configuration message and an indication of an adjustment amount of the first clock.

2 . The arrangement of claim 1 , wherein the synchronization information is dependent on at least the first time-stamp, and wherein the synchronization information comprises an indication of a first time difference between the time of sending the time information request message as indicated by the first time-stamp and a time of receiving the time information request message.

3 . The arrangement of claim 2 , wherein the synchronization information comprises a third time-stamp of a time of sending the time information response message, and wherein the first processor is configured to determine a synchronization deviation between the first clock and the second clock based on the first time difference and a second time difference between the time of sending the time information response message as indicated by the third time-stamp and a time of receiving the time information response message.

4 . The arrangement of claim 3 , wherein the first processor is configured to determine a round-trip latency based on the first time difference and the second time difference, and determine the synchronization deviation further based on the round-trip latency.

5 . The arrangement of claim 4 , wherein the first processor is configured to synchronize the first clock by adjusting the first clock such that the determined synchronization deviation is compensated, and wherein the first processor is configured to perform multiple cycles of sending the time information request message and receiving the time information response message, determine the synchronization deviation for each pair of time information request message and time information response message, and adjust the first clock such that a smallest of the determined synchronization deviations is compensated or such that an average of the determined synchronization deviations is compensated.

6 . A wireless mobile device for receiving medical data from a wireless head-wearable sensor arrangement, the wireless mobile device comprising:

a second wireless interface;

a second clock; and

a second processor configured to:

perform a time-synchronization procedure to synchronize the second clock with a first clock of the wireless head-wearable sensor arrangement or to instruct synchronization of the first clock of the wireless head-wearable sensor arrangement with the second clock; and

after having performed the time-synchronization procedure, receive the medical data from the wireless head-wearable sensor arrangement via the second wireless interface and send the medical data to a computing system, the medical data comprising a representation of at least one measurement of a biosignal of a user wearing the wireless head-wearable sensor arrangement and at least one time-stamp allocated to the at least one measurement,

wherein the second processor is configured to:

receive a time information request message from the wireless head-wearable sensor arrangement via the second wireless interface, the time information request message comprising a first time-stamp of a time of sending the time information request message;

determine synchronization information based at least on information comprised in the time information request message; and

send a time information response message to the wireless head-wearable sensor arrangement via the second wireless interface, the time information response message comprising the synchronization information,

wherein the second processor is configured to, after having sent the time information response message, receive a configuration message from the wireless head-wearable sensor arrangement via the second wireless interface, the configuration message comprising an indication of an adjustment amount of the first clock and a second time-stamp of a time of sending the configuration message.

7 . The device of claim 6 , wherein the synchronization information is dependent on at least the first time-stamp, and wherein the synchronization information comprises an indication of a first time difference between the time of sending the time information request message as indicated by the first time-stamp and a time of receiving the time information request message.

8 . The device of claim 7 , wherein the synchronization information comprises a third time-stamp of a time of sending the time information response message, and wherein the second processor is configured to determine a synchronization deviation between the first clock and the second clock based on the first time difference and a second time difference between the time of sending the time information response message as indicated by the third time-stamp and a time of receiving the time information response message.

9 . The device of claim 6 , wherein:

the second processor is configured to receive a time synchronization request message from the wireless head-wearable sensor arrangement via the second wireless interface and to start performing the time-synchronization procedure in response to receiving the time synchronization request message;

the time synchronization request message comprises a fourth time-stamp of a time of sending the time synchronization request message and the second processor is configured to pre-adjust the second clock based on the time of sending the time synchronization request message as indicated by the fourth time-stamp, before performing the time-synchronization procedure; and

the second processor is configured to pre-adjust the second clock if the time indicated by the fourth time-stamp deviates more than a predefined amount from a time of receiving the time synchronization request message.

10 . The device of claim 6 , wherein:

the second processor is configured to send a time synchronization request message to the wireless head-wearable sensor arrangement via the second wireless interface to trigger the wireless head-wearable sensor arrangement to start performing the time-synchronization procedure;

the time synchronization request message comprises a fourth time-stamp of a time of sending the time synchronization request message and instructs the head-wearable sensor arrangement to pre-adjust the first clock based on the time of sending the time synchronization request message as indicated by the fourth time-stamp, before performing the time-synchronization procedure; and

the time synchronization request message instructs the wireless head-wearable sensor arrangement to pre-adjust the first clock if the time indicated by the fourth time-stamp deviates more than a predefined amount from a time of receiving the time synchronization request message.

11 . A computing system for receiving medical data from a wireless mobile device, the computing system comprising one or more processors configured to:

receive, from the wireless mobile device comprising a second clock, medical data comprising a representation of at least one measurement of a biosignal of a user wearing a wireless head-wearable sensor arrangement and at least one time-stamp allocated to the at least one measurement, the wireless head-wearable sensor arrangement comprising a first clock; and

determine, based on the representation of the at least one measurement and the at least one time-stamp allocated to the at least one measurement, an indicator of health, well-being or performance of the user of the wireless head-wearable sensor arrangement,

wherein the one or more processors are configured to receive, from the wireless mobile device,

an indication of an adjustment amount of either the first clock or the second clock used for synchronizing the first clock or the second clock, or

an adjustment amount instruction used for synchronizing the first clock or the second clock, and

wherein the one or more processors are configured to determine the indicator of health, well-being or performance of the user further based on the indication of the adjustment amount or the adjustment amount instruction.

12 . The system of claim 11 , wherein the one or more processors are configured to receive a time-association between the adjustment amount and the at least one measurement, or between the adjustment amount instruction and the at least one measurement from the wireless mobile device, and

wherein the one or more processors are configured to determine the indicator of health, well-being or performance of the user further based on the time-association.

13 . The system of claim 11 , wherein the one or more processors are configured to:

receive, from the wireless mobile device, an indication of one or more stimulus time points at which at least one stimulus is provided to the user,

wherein the one or more processors are configured to determine the indicator of health, well-being or performance of the user further based on the indication of the one or more stimulus time points, and wherein the indication of the one or more stimulus time points comprises a time-association between the one or more stimulus time points and the at least one measurement.

14 . The system of claim 11 , wherein the one or more processors are configured to receive, from the wireless mobile device, user data describing a user input received via a user interface of the wireless mobile device, and wherein the one or more processors are configured to determine the indicator of health, well-being or performance of the user further based on the user data, and wherein the user data comprises a time-association between one or more time points of received user input and the at least one measurement.

15 . The system of claim 11 , wherein the one or more processors are configured to determine at least one time-adjusted measurement by performing one or more of:

adjusting at least a part of the representation of the at least one measurement in time based on at least some information received from the wireless mobile device, and determining the indicator of health, well-being or performance of the user of the wireless head-wearable sensor arrangement based on the at least one time-adjusted measurement; and

adjusting the at least one time-stamp allocated to the at least one measurement in time based on the at least some information received from the wireless mobile device, and determining the indicator of health, well-being or performance of the user of the wireless head-wearable sensor arrangement further based on the at least one time-adjusted time-stamp.

16 . A medical data processing system comprising at least two of the following:

a computing system;

a wireless head-wearable sensor arrangement; or

a wireless mobile device comprising:

a second wireless interface;

a second clock; and

a second processor configured to:

perform a time-synchronization procedure to synchronize the second clock with a first clock of the wireless head-wearable sensor arrangement or to instruct synchronization of the first clock of the wireless head-wearable sensor arrangement with the second clock; and

after having performed the time-synchronization procedure, receive medical data from the wireless head-wearable sensor arrangement via the second wireless interface and send the medical data to the computing system, the medical data comprising a representation of at least one measurement of a biosignal of a user wearing the wireless head-wearable sensor arrangement and at least one time-stamp allocated to the at least one measurement, wherein the second processor is configured to perform the time-synchronization procedure by:

sending a time information request message to the wireless head-wearable sensor arrangement via the second wireless interface, the time information request message comprising a first time-stamp of a time of sending the time information request message; and

receiving a time information response message from the wireless head-wearable sensor arrangement via the second wireless interface, the time information response message comprising synchronization information, wherein the second processor is configured to synchronize the second clock by adjusting the second clock based at least on the synchronization information, and wherein the second processor is configured to, after having adjusted the second clock, send a configuration message to the wireless head-wearable sensor arrangement via the second wireless interface, the configuration message comprising at least one of a second time-stamp of a time of sending the configuration message and an indication of an adjustment amount of the second clock.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 15, 2026
From: MURPHY, BRIAN; TREMBLAY, YANNICK; NOLAN, HUGH; SHAW, MATTHEW
To: CUMULUS NEUROSCIENCE LTD
Reel/Frame 074672/0265 →
Continuity (1)
Related Publication 20240259966A1 · Aug 1, 2024
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