Granted Patent
B2
US 12,673,076 · App. 15/034,500 · Granted Jul 7, 2026
Lactobactilus plantarum 2830 (ECGC 13110402) for use in treatments
Assignee:
PROBIOTIX LIMITED
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Abstract
The present invention relates to one or more strains of Lactobacilli and a cholesterol modifying agent (such as an oligosaccharide) for use in modifying the absorption of cholesterol in an individual or the treatment of heart disease, diabetes or obesity.
Claims (14)
1 . A composition comprising a strain of Lactobacilli having an elevated bile salt hydrolase activity and a galactooligosaccharide; wherein the strain is Lactobacillus plantarum 2830 (ECGC 13110402),
wherein the galactooligosaccharide is produced by the strain by reverse β-galactosidase reaction, and wherein
the composition further comprises an excipient and/or carrier compound;
the composition is in the form of a food stuff or a food additive;
the Lactobacillus plantarum 2830 is freeze-dried;
the composition further comprises at least one selected from: vitamins, minerals, phytochemicals and/or antioxidants; or
a combination thereof.
2 . The composition of claim 1 for modifying the absorption of cholesterol in an individual.
3 . The composition of claim 1 for treatment of high cholesterol, heart disease, diabetes or obesity.
4 . The composition of claim 1 , wherein the galactooligosaccharide comprises a selective growth medium for the strain of Lactobacilli.
5 . The composition of claim 1 , wherein the composition is encapsulated.
6 . The composition of claim 1 , in the form of a foodstuff and/or for use as a dietary supplement.
7 . The composition of claim 1 , further comprising a prebiotic.
8 . A method of producing a composition, the method comprising: mixing a composition according to claim 1 with a cholesterol modifying agent in a biologically effective amount.
Assignments (4)
CHANGE OF NAME
Recorded Jun 4, 2026
From: PROBIOTIX HEALTH LIMITED
To: PROBIOTIX LIMITED
Reel/Frame 074853/0575 →
CONFIRMATORY LICENSE
Recorded Dec 22, 2021
From: OPTIBIOTIX LIMITED
To: OPTIBIOTIX HEALTH PLC
Reel/Frame 058457/0937 →
CONFIRMATORY LICENSE
Recorded Dec 22, 2021
From: OPTIBIOTIX HEALTH PLC
To: PROBIOTIX HEALTH LIMITED
Reel/Frame 058458/0089 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 2, 2020
From: O'HARA, STEPHEN PATRICK
To: OPTIBIOTIX LIMITED
Reel/Frame 053668/0731 →
Priority Claims (1)
GB 1319538
· Nov 5, 2013
· national
Continuity (1)
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