Granted Patent
B2
US 12,691,050 · App. 18/003,127 · Granted Jul 28, 2026
Fragrance release mechanism, method and uses thereof
Inventors:
Artur Manuel Cavaco Paulo (Braga, PT); Filipa Daniela Gomes Gonçalves (Braga, PT); Artur Jorge Araújo Magalhães Ribeiro (Braga, PT); Carla Manuela Pereira Marinho Da Silva (Guimaraes, PT)
Assignee:
UNIVERSIDADE DO MINHO
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Abstract
A release composition comprising a protein and an active agent, wherein the active agent is released when in presence of an electrolyte solution is described. A kit and an article comprising the release composition of the present-subject matter are also encompassed.
Claims (21)
1 . A composition comprising:
0.01 to 5000 μM of an odorant binding protein comprising an amino acid sequence of SEQ ID NO: 21; and
0.1 μM to 2 M of an active agent, wherein the active agent is a deodorizing agent, a natural essence, a fragrance, a moisturizing agent, or a combination of two or more thereof,
wherein the active agent is released from the odorant binding protein in the presence of an electrolyte solution at a temperature of about 10° C. to about 70° C.,
wherein the active agent has a molecular weight from 20 to 1000 g/mol, and
wherein the electrolyte solution comprises sweat, salty water or micellar water.
2 . The composition according to claim 1 , wherein the active agent is present at a concentration of about 0.2 μM to about 1 M.
3 . The composition according to claim 1 , wherein the odorant binding protein has an affinity constant to the active agent in water or a buffer solution of about 1 μM to about 4.5 μM.
4 . The composition according to claim 1 , wherein the odorant binding protein has an affinity constant to the active agent in an electrolyte solution of about 0.1 μM to about 0.99 μM.
5 . The composition according to claim 1 , wherein the active agent has a molecular weight from 75-300 g/mol.
6 . The composition according to claim 1 , wherein the active agent is a fragrance molecule.
7 . The composition according to claim 1 , wherein the active agent is a fragrance molecule comprising 2-acetyl-1-pyrroline, α-terpineol, β-ocimene, benzyl acetate, butyl acetate, camphor, carvone, citral, citronellol, coumarin, diacetyl, eugenol, fructone, gamma decalactone, gamma nonalactone, geraniol, hedione, isoamyl acetate, lilac aldehyde, limonene, linalool, mefrosol, menthol, methyl butyrate, myrcene, pinene, pomarose, pulegone, sandalore, vanillin, or a combination of two or more thereof.
8 . The composition according to claim 1 , wherein the active agent is released over about 30 seconds to about 24 hours.
9 . The composition according to claim 1 , wherein the odorant binding protein is stable in polar and non-polar solvents, wherein the polar and non-polar solvents comprise ethanol, methanol, butanol, benzene and undecanol.
10 . The composition according to claim 1 , wherein the odorant binding protein is stable at temperatures of about 18° C. to about 70° C.
11 . The composition according to claim 1 , wherein the odorant binding protein is stable in a pH range of about 4.0 to about 10.0.
12 . The composition according to claim 1 , further comprising glycerol, erythritol, arabitol, sorbitol, mannitol, xylitol, mannitol, glucosylglycerol, glucose, fructose, sucrose, trehalose, isofluoroside, dextrans, levans, polyethylene glycol, salts of chloride, citrate, sulfates, acetate, or phosphates, or a combination of two or more thereof.
13 . The composition according to claim 1 , wherein the composition is used as a cosmetic composition.
14 . The composition according to claim 13 , wherein the composition is used as a deodorant composition.
15 . A kit or article comprising the composition according to claim 1 .
16 . The kit or article according to claim 15 , wherein the article is selected from the group consisting of fabric, textiles, fibers, clothes, scarfs, hats, gloves, socks and turbans, shoes, insoles, bags, handbags, detergents, creams, lotions, foams, perfumes, softeners, aerosols, deodorants, lipsticks, lip creams, face mask powders, face and body creams, skin clarifiers, primers, foundations, eyelash mascaras, hair shampoos, hair serum, hairs masks, hair conditioners or hair coloration creams.
Priority Claims (2)
PT 116561
· Jul 3, 2020
· national
EP 20206292
· Nov 6, 2020
· regional
Continuity (1)
Related Publication
20230248631A1
· Aug 10, 2023
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