Granted Patent
B2
US 12,383,484 · App. 18/497,900 · Granted Aug 12, 2025
Peptide composition and respective uses
Inventors:
Artur Manuel Cavaco Paulo (Braga, PT); Celia Freitas Da Cruz (Guimaraes, PT); Margarida Maria Macedo Francesko Fernandes (Braga, PT)
Assignee:
UNIVERSIDADE DO MINHO
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Abstract
The current application discloses a composition that comprises at least one peptide with a sequence length of 6-12 amino acids, where 2-5 of those amino acids are cysteines for the treatment and cosmetics of animal hair, in preference human hair. There are several hair styling methods that involve breakage and reestablishment of disulfide bonds, allowing relaxation and straightening of the hair. However, the most effective methods currently used to modulate hair contain harmful chemicals. Thus, there is a constant demand for formulations that efficiently model the hair fiber without damage. Thus, the present invention aims to provide a composition for treatment of the hair, including animal and human hair, without the use of chemicals harmful to the hair fiber and consumer health and uses of said compositions in shampoo, lotion, serum, cream, conditioner, foam, elixir, oil, aerosol or mask.
Claims (25)
1. A hair composition comprising:
a keratin peptide fragment having about 15% to about 30% cysteine amino acid content, wherein the keratin peptide fragment comprises a peptide sequence at least 90% identical to SEQ ID NO: 412 or SEQ ID NO: 409;
wherein the hair composition is a lotion or cream.
2. The hair composition of claim 1 , wherein the peptide sequence of the keratin peptide fragment is at least 95% identical to SEQ ID NO: 412.
3. The hair composition of claim 1 , wherein the peptide sequence of the keratin peptide fragment is at least 95% identical to SEQ ID NO: 409.
4. The hair composition of claim 1 , wherein the peptide sequence of the keratin peptide fragment is identical to SEQ ID NO: 412.
5. The hair composition of claim 1 , wherein the peptide sequence of the keratin peptide fragment is identical to SEQ ID NO: 409.
6. The hair composition of claim 1 , wherein the keratin peptide fragment forms one or more molecular interactions with hair.
7. The hair composition of claim 6 , wherein the one or more molecular interactions is one or more disulfide bonds.
8. The hair composition of claim 1 , wherein the total number of cysteine amino acids in the keratin peptide fragment is 2 cysteine amino acids.
9. A hair composition comprising:
a keratin peptide fragment having about 15% to about 30% cysteine amino acid content, wherein the keratin peptide fragment comprises a peptide sequence at least 90% identical to SEQ ID NO: 412 or SEQ ID NO: 409; and
at least one excipient comprising propylene glycol, polysorbate 20, hydrolyzed wheat protein, hydrolyzed wheat starch, potassium sorbate, or an alcohol, or a combination of two or more thereof,
wherein the total number of cysteine amino acids in the keratin peptide fragment is 2 cysteine amino acids.
10. The hair composition of claim 9 , wherein the at least one excipient further comprises ether dicaprylic, cetyl ester, behentrimonium chloride, or tocopherol, or a combination of two or more thereof.
11. The hair composition of claim 9 , wherein the at least one excipient further comprises potassium hydroxide, acrylate, or phenoxyethanol, or a combination or two or more thereof.
12. The hair composition of claim 9 , wherein the peptide sequence of the keratin peptide fragment is identical to SEQ ID NO: 412.
13. The hair composition of claim 9 , wherein the peptide sequence of the keratin peptide fragment is identical to SEQ ID NO: 409.
14. A hair composition comprising:
a keratin peptide fragment having about 15% to about 30% cysteine amino acid content, wherein the keratin peptide fragment comprises a peptide sequence at least 90% identical to SEQ ID NO: 412 or SEQ ID NO: 409; and
at least one excipient comprising an oil and/or an alcohol,
wherein the total number of cysteine amino acids in the keratin peptide fragment is 2 cysteine amino acids.
15. The hair composition of claim 14 , comprising the oil and the alcohol.
16. The hair composition of claim 14 , wherein the peptide sequence of the keratin peptide fragment is identical to SEQ ID NO: 412.
17. The hair composition of claim 14 , wherein the peptide sequence of the keratin peptide fragment is identical to SEQ ID NO: 409.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 31, 2023
From: CAVACO PAULO, ARTUR MANUEL; FREITAS DA CRUZ, CELIA; MACEDO FRANCESKO FERNANDES, MARGARIDA MARIA
To: UNIVERSIDADE DO MINHO
Reel/Frame 065415/0085 →
Priority Claims (1)
PT 107244
· Oct 18, 2013
· national
Continuity (5)
Continuation
15030313
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