Peptide composition and respective uses
The current application discloses a composition that comprises at least one peptide with a sequence length of 6-12 amino acids, where 2-5 of those amino acids are cysteines for the treatment and cosmetics of animal hair, in preference human hair. There are several hair styling methods that involve breakage and reestablishment of disulfide bonds, allowing relaxation and straightening of the hair. However, the most effective methods currently used to modulate hair contain harmful chemicals. Thus there is a constant demand for formulations that efficiently model the hair fiber without damage. Thus, the present invention aims to provide a composition for treatment of the hair, including animal and human hair, without the use of chemicals harmful to the hair fiber and consumer health and uses of said compositions in shampoo, lotion, serum, cream, conditioner, foam, elixir, oil, aerosol or mask.
1. A peptide composition for hair treatment comprising: a keratin peptide fragment having 10% to 50% cysteine amino acid content, wherein the total number of cysteine amino acids in the keratin peptide fragment is 2-5 cysteine amino acids and the keratin peptide fragment comprises any one of SEQ ID NO: 5, SEQ ID NO: 75, SEQ ID NO: 409, SEQ ID NO: 412, SEQ ID NO: 1088, and SEQ ID NO: 1131, and wherein the keratin peptide fragment is present in the peptide composition at 0.001% to 20% (w/w).
2. The peptide composition of claim 1 , wherein the total number of cysteine amino acids in the keratin peptide fragment is 2 cysteine amino acids.
3. The peptide composition of claim 1 , wherein the concentration of the keratin peptide fragment in the peptide composition is 0.01% to 5% (w/w).
4. The peptide composition of claim 1 , comprising a dyeing agent or dye linked to the N or C terminal of the keratin peptide fragment.
5. The peptide composition of claim 1 for use in improving hair elasticity and strength.
6. The peptide composition of claim 1 for treatment of a hair scalp disease.
7. The peptide composition of claim 6 , wherein the hair scalp disease is scalp irritation, alopecia areata, lichen planus, folliculitis keloid of the neck, trichorrhexis nodosa, tricodistrophy, pili torti, tricorrexis invaginata, moniletrix, or uncombable hair syndrome.
8. The peptide composition of claim 1 , wherein the concentration of the keratin peptide fragment in the peptide composition is 0.001% to 1% (w/w).