IP Library › Granted Patent US 12,698,417
Granted Patent B2
US 12,698,417 · App. 18/069,508 · Granted Aug 4, 2026

Coatings containing polymer modified enzyme for stable self-cleaning of organic stains

Inventors: Hongfei Jia (Ann Arbor, MI); Ping Wang (North Oaks, MN); Liting Zhang (St. Paul, MN); Andreas Buthe (Steinfurt, DE); Xueyan Zhao (Circle Pines, MN); Songtao Wu (Ann Arbor, MI); Masahiko Ishii (Okazaki City, JP); Minjuan Zhang (Ann Arbor, MI)
Assignees: TOYOTA MOTOR CORPORATION; Regents of the University of Minnesota
C09D189/00A61K47/60C08G65/33337C09D5/024C09D5/16C09D7/40C09D175/16C12N9/14C12N9/20C12N9/2408C12N9/2411C12N9/54C12N9/96C12N11/06C12N11/089C08L2203/02C08L2205/02
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Quick Facts
Patent No.
US 12,698,417
App. No.
18/069,508
Filed
Dec 21, 2022
Granted
Aug 4, 2026
Kind
B2
Art Unit
1657
USPC
524/17
Abstract

A process of stabilizing the activity of an enzyme against inactivation by water weathering are provided including associating one or more polymeric moieties of a polyoxyethylene having a molecular weight of 10,000 Daltons or greater with an enzyme to form a chemically modified enzyme; and dispersing said chemically modified enzyme in a base to form a water-stabilized active coating material.

Claims (10)

1 . A process of stabilizing the activity of an enzyme against water weathering in a coating composition comprising:

associating one or more polymeric moieties of a polyoxyethylene having a molecular weight of 10,000 Daltons or greater with an enzyme to form a chemically modified enzyme; and

dispersing said chemically modified enzyme in a base to form a water-stabilized active coating material.

2 . The process of claim 1 wherein said dispersing results in protein particles with an average particle diameter of less than 5 micrometers.

3 . The process of claim 1 further comprising coating a substrate with said active coating material such that said enzyme is capable of enzymatically degrading a component of an organic stain in contact with said active coating material.

4 . The process of claim 1 wherein said enzyme is a hydrolase.

5 . The process of claim 1 wherein said polyoxyethylene has a molecular weight between 1,000 and 15,000 Daltons.

6 . The process of claim 1 wherein said enzyme is an amylase.

7 . The process of claim 1 wherein said polyoxyethylene has a molecular weight of 10,000 Daltons to 20,000 Daltons.

8 . The process of claim 1 wherein said polyoxyethylene has a molecular weight of 12,000 Daltons or greater.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 17, 2024
From: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC.
To: TOYOTA MOTOR CORPORATION
Reel/Frame 067444/0430 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2023
From: JIA, HONGFEI; WU, SONGTAO; ZHANG, MINJUAN
To: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC.
Reel/Frame 064107/0965 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2023
From: WANG, PING; ZHANG, LITING; BUTHE, ANDREAS; ZHAO, XUEYAN
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 064108/0134 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2023
From: ISHII, MASAHIKO
To: TOYOTA MOTOR CORPORATION
Reel/Frame 064108/0041 →
Continuity (4)
Division 16258567 · Jan 26, 2019
Continuation 14812087 · Jul 29, 2015
Continuation 13229277 · Sep 9, 2011
Related Publication 20230212426A1 · Jul 6, 2023
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