IP Library Granted Patent US 12,723,283
Granted Patent B2
US 12,723,283 · App. 17/386,594 · Granted Sep 1, 2026

Combination of soybean whole genome SNP loci, gene chip and application thereof

Inventors: Xianzhong Feng (Changchun city, CN); Hui Yu (Changchun city, CN); Jiantian Leng (Changchun city, CN); Huangkai Zhou (Changchun city, CN); Guang Li (Changchun city, CN); Kuanqiang Tang (Changchun city, CN); Beifang Zhao (Changchun city, CN)
Assignee: NORTHEAST INSTITUTE OF GEOGRAPHY AND AGROECOLOGY, CHINESE ACADEMY OF SCIENCES
C12Q1/6895C12Q1/6837G16B20/20C12Q2600/156C40B40/06
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,723,283
App. No.
17/386,594
Granted
Sep 1, 2026
Kind
B2
Abstract

The present invention relates to a combination of soybean whole genome SNP loci, a gene chip and an application thereof. The combination of soybean whole genome SNP loci includes 20,648 SNP loci, which are shown as S00001-20648. The gene chip provided by the present invention has extremely high coverage on functional genes, the SNP marker loci cover 17,096 functional genes of soybean, accounting for about 31% of the total number of soybean genes, and the SNP marker loci are located in gene coding regions. Among the 20,648 SNP marker loci, 17,588 SNP marker loci are located on genes, accounting for 85% of the total number of the SNP marker loci. Therefore, when those SNP marker loci are applied in molecular assisted breeding or whole genome selective breeding, they can accelerate the breeding process.

Claims (2)

1 . A gene chip for detecting a combination of soybean whole genome single nucleotide polymorphism (SNP) loci, wherein the gene chip is a liquid-phase chip containing a set of polynucleotide probes for the soybean whole genome SNP loci that comprise 20,648 SNP loci, wherein each of SNP loci contains two different nucleotide variation positions for detecting allelic changes of the locus, wherein the physical positions of the 20,648 SNP loci are determined on the basis of the whole genome sequence alignment of soybean variety Williams82, the version number of the whole genome sequence of the soybean variety Williams82 is Glycine max Wm82.a2.v1, and the 20,648 SNP loci are shown as S00001-20648.

2 . The gene chip according to claim 1 , wherein a solution system of the liquid-phase chip is nuclease-free water, and the concentration of the probes in the solution system is 60 ng/μL.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2021
From: FENG, XIANZHONG; YU, HUI; LENG, JIANTIAN; ZHOU, HUANGKAI; LI, GUANG; TANG, KUANQIANG; ZHAO, BEIFANG
To: NORTHEAST INSTITUTE OF GEOGRAPHY AND AGROECOLOGY,CHINESE ACADEMY OF SCIENCES
Reel/Frame 056999/0453 →
Priority Claims (1)
CN 202011633836.7 · Dec 31, 2020 · national
Continuity (1)
Related Publication 20220205053A1 · Jun 30, 2022
References Cited (8)
US 20140007304A1 · Wang et al. · 2014 [cited by applicant]
CN 105567857A · 2016 [cited by applicant]
CN 110698551A · 2020 [cited by applicant]
CN 111676308A · 2020 [cited by applicant]
Elshire et al., “A Robust, Simple Genotyping-by-Sequencing (GBS) Approach for High Diversity Species,” PLoS ONE 2011, 6(5): e19379. (Year: 2011). [cited by examiner]
Song, Q., et al., “Development and Evaluation of SoySNP50K, a High-Density Genotyping Array for Soybean.” PLos One, Jan. 2013, 8(1): e54985, pp. 1-12. [cited by applicant]
Wang, J., et al., “Development and application of a novel genome-wide SNP array reveals domestication history in soybean.” Scientific Reports, 2016, 6(1): 20728, pp. 1-10. [cited by applicant]
Wang, Y., et al., “Genotyping of Soybean Cultivars with Medium-Density Array Reveals the Population Structure and QTNs Underlying Maturity and Seed Traits.” Frontiers in Plant Science, May 2018, 9(610): pp. 1-16. [cited by applicant]