IP Library › Granted Patent US 12,727,847
Granted Patent B2
US 12,727,847 · App. 18/864,048 · Granted Sep 8, 2026

Continuous blood pressure measurement system and method

Inventors: Rohan Joshi (Eindhoven, NL); Sergei Y. Shulepov (Eindhoven, NL); Kevin Daniel Seng Hung Lau (Eindhoven, NL)
Assignee: KONINKLIJKE PHILIPS N.V.
A61B8/06A61B8/488
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Quick Facts
Patent No.
US 12,727,847
App. No.
18/864,048
Granted
Sep 8, 2026
Kind
B2
Abstract

A system and method for measuring blood pressure makes flow velocity measurements from an artery location and vessel diameter measurements from the same artery location, using an ultrasound system. An arterial wave velocity is obtained from the blood flow velocity and vessel diameter and changes in blood pressure are then tracked. A continuous blood pressure estimate is made from intermittent cuff measurements together with tracked changes in blood pressure between those intermittent measurements.

Claims (46)

1 . A method of measuring blood pressure, the method comprising:

receiving ultrasound blood flow velocity measurements from an artery location; and

receiving ultrasound vessel diameter measurements from the same artery location using the same, single ultrasound system;

determining an arterial wave velocity from a diameter-velocity loop relating a blood flow velocity and a vessel diameter;

tracking changes in blood pressure based on the arterial wave velocity and the blood flow velocity measurements;

obtaining an intermittently measured blood pressure from a cuff; and

deriving a continuous blood pressure estimate from the intermittent measurements and the tracked changes in blood pressure between those intermittent measurements.

2 . The method of claim 1 , comprising:

receiving pulsed wave Doppler ultrasound blood flow velocity measurements from the artery location; and

receiving B-mode ultrasound vessel diameter measurements from the same artery location.

3 . The method of claim 1 , comprising obtaining the arterial wave velocity from the rate of change of blood flow velocity with respect to a logarithm of the diameter.

4 . The method of claim 1 , comprising setting the timing of a next cuff measurement based on a level of change of the arterial wave velocity.

5 . The method of claim 4 comprising identifying a change in arterial wave velocity that is a predetermined factor more than a threshold level of hemodynamic change.

6 . The method of claim 1 , further comprising estimating cardiac output from the blood flow velocity measurement and vessel diameter measurement.

7 . A blood pressure analysis system, comprising:

a single ultrasound system; and

a processor,

wherein the processor is configured to:

receive blood flow velocity measurements from an artery location taken by the ultrasound system;

receive vessel diameter measurements from the same artery location taken by the ultrasound system;

determine; an arterial wave velocity from a diameter-velocity loop relating a blood flow velocity and a vessel diameter;

track changes in blood pressure based on the arterial wave velocity and the blood flow velocity measurements;

receive an intermittently measured blood pressure from a cuff; and

derive a continuous blood pressure estimate from the intermittent measurements and the tracked changes in blood pressure between those intermittent measurements.

8 . The blood pressure analysis system of claim 7 , wherein the processor is configured to set the timing of a next cuff measurement based on a level of change of the arterial wave velocity.

9 . The blood pressure analysis system of claim 8 , wherein the processor is configured to identify a change in arterial wave velocity that is a predetermined factor more than a threshold level of hemodynamic change.

10 . The blood pressure analysis system of claim 7 , wherein the processor is configured to estimate a cardiac output from a blood flow velocity measurement and a vessel diameter measurement.

11 . The blood pressure analysis system of claim 7 , wherein the processor is configured to obtain the arterial wave velocity from the rate of change of blood flow velocity with respect to a logarithm of the diameter.

12 . A blood pressure measurement system, comprising:

a blood pressure measurement cuff; and

a blood pressure analysis system comprising:

a single ultrasound system configured to:

obtain blood flow velocity measurements from an artery location; and

obtain vessel diameter measurements from the same artery location; and

a processor, wherein the processor is configured to:

receive the blood flow velocity measurements from the artery location taken by the single ultrasound system;

receive the vessel diameter measurements from the same artery location taken by the single ultrasound system;

determine an arterial wave velocity from a diameter-velocity loop relating a blood flow velocity and a vessel diameter;

track changes in blood pressure based on the arterial wave velocity and the blood flow velocity measurements;

receive an intermittently measured blood pressure from the blood pressure measurement cuff; and

derive a continuous blood pressure estimate from the intermittent measurements and the tracked changes in blood pressure between those intermittent measurements.

13 . The blood pressure measurement system of claim 12 , wherein the ultrasound system comprises an ultrasound patch.

14 . The blood pressure measurement system of claim 12 , wherein the ultrasound system is configured to:

obtain the vessel diameter measurements by B-mode ultrasound imaging; and

obtain the blood flow velocity measurements by pulsed wave Doppler ultrasound.

15 . A non-transitory computer-readable medium that stores therein a computer program product, which, when executed on a processor, causes the processor to perform the method of claim 1 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 8, 2024
From: JOSHI, ROHAN; SHULEPOV, SERGEI Y.; LAU, KEVIN DANIEL SENG HUNG
To: KONINKLIJKE PHILIPS N.V.
Reel/Frame 069214/0739 →
Priority Claims (1)
EP 22172251 · May 9, 2022 · regional
Continuity (1)
Related Publication 20250331804A1 · Oct 30, 2025
References Cited (19)
US 7125383B2 · Hoctor · 2006 [cited by applicant]
US 9603533B2 · Lading · 2017 [cited by examiner]
US 12564370B2 · Joshi · 2026 [cited by examiner]
US 20020055680A1 · Miele · 2002 [cited by examiner]
US 20020173693A1 · Landesberg · 2002 [cited by examiner]
US 20040059234A1 · Martin · 2004 [cited by examiner]
US 20050143640A1 · Hoctor · 2005 [cited by applicant]
US 20060211942A1 · Hoctor · 2006 [cited by examiner]
US 20080177131A1 · Dancu · 2008 [cited by examiner]
US 20100106016A1 · Orbay · 2010 [cited by applicant]
US 20130178736A1 · Pahlevan · 2013 [cited by examiner]
US 20150230774A1 · Thai · 2015 [cited by applicant]
US 20170181643A1 · Pahlevan · 2017 [cited by examiner]
US 20170281018A1 · Kramer · 2017 [cited by examiner]
EP 3513717A1 · 2019 [cited by applicant]
WO WO2021250234A2 · 2021 [cited by examiner]
International Search Report Dated Jul. 14, 2023 for International Appln. No. PCT/EP-2023/061427 Filed May 1, 2023. [cited by applicant]
Feng J et al: “Determination of Wave Speed and Wave Separation inthe Arterites Using Diameter and Velocity”, Journal of Biomechanics, Pergamon Press, NY. vol, 43, No. 3 Feb. 10, 2010, pp. 455-462. [cited by applicant]
V. Sheshadri, A. Tiwari, M. Nagappa, and L. Venkatraghavan, “Accuracy in blood pressure monitoring: The effect of noninvasive blood pressure cuff inflation on intra-arterial blood pressure values,” Anesth. Essays Res., … [cited by applicant]