IP Library Granted Patent US 12,733,664
Granted Patent B2
US 12,733,664 · App. 18/262,515 · Granted Sep 15, 2026

Hydroxy- and methoxy-substituted flavones and their use

Inventors: Wen-Juan Xiang (Shanghai, CN); Dan-Ting Yin (Shanghai, CN); Wen-Ting Zhu (Shanghai, CN)
Assignee: Firmenich SA
A23L27/2052A23L27/84A23L27/86A23L27/88
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Quick Facts
Patent No.
US 12,733,664
App. No.
18/262,515
Granted
Sep 15, 2026
Kind
B2
Abstract

The present disclosure generally provides uses of certain mixed hydroxy- and methoxy-substituted flavones (HMFs) to reduce bitterness, astringency, or sourness, or to enhance sweetness of a ingestible composition, such as a flavored food or beverage product. In some embodiments, the disclosure provides uses of the HMFs disclosed herein to reduce the unpleasant taste of limonin, nomelin, or naringin, which can be present at elevated levels in certain citrus products.

Claims (17)

1 . A method of enhancing a sweet taste, reducing a bitter taste, reducing a sour taste, or reducing an astringent taste, of an ingestible composition, the method comprising introducing to the ingestible composition a flavor-modifying compound, wherein the flavor-modifying compound is selected from the group consisting of:

4′-hydroxy-5,6,7,3′-tetramethoxyflavone;

4′-hydroxy-3,5,6,7,3′-pentamethoxyflavone;

4′-hydroxy-5,6,7-trimethoxyflavone;

4′-hydroxy-3,5,6,7,8,3′-hexamethoxyflavone;

4′-hydroxy-5,6,7,8-tetramethoxyflavone;

3′-hydroxy-3,5,6,7,4′-pentamethoxyflavone;

3′-hydroxy-3,5,6,7,8,4′-hexamethoxyflavone;

any comestibly acceptable salts of the foregoing; and

any combination thereof.

2 . The method of claim 1 , wherein the flavor-modifying compound is present in the ingestible composition at a concentration ranging from 0.01 ppm to 1000 ppm, based on the total weight of the ingestible composition.

3 . The method of claim 1 , wherein the ingestible composition comprises one or more bitter compounds.

4 . The method of claim 3 , wherein the one or more bitter compounds comprise limonin, nomilin, naringin, or any combinations thereof.

5 . The method of claim 4 , wherein the ingestible composition is a citrus fruit juice.

6 . The method of claim 3 , wherein the ingestible composition is coffee, tea, fruit juice, or any combination thereof.

7 . The method of claim 1 , wherein the ingestible composition comprises one or more non-animal proteins.

8 . The method of claim 1 , wherein the ingestible composition comprises a sweetener.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 22, 2025
From: XIANG, WEN-JUAN; YIN, DAN-TING; ZHU, WEN-TING
To: FIRMENICH SA
Reel/Frame 072637/0402 →
Priority Claims (2)
WO PCT/CN2021/079733 · Mar 9, 2021 · international
EP 21164343 · Mar 23, 2021 · regional
Continuity (1)
Related Publication 20240114939A1 · Apr 11, 2024
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