Compositions and methods
An amorphous solid for use in aerosol generation, the amorphous solid including about 1 to about 50 wt % constituent, derivative or extract of cannabis ; about 10 to about 80 wt % aerosol-former material; gelling agent, the gelling agent having cellulose or a derivative thereof, and a non-cellulosic gelling agent; and optionally filler, wherein the amount of gelling agent and optional filler taken together is from about 10 to about 60 wt %; wherein the wt % values are calculated on a dry weight basis.
1 . An amorphous solid for use in aerosol generation, the amorphous solid comprising:
about 1 to about 50 wt % constituent, derivative or extract of cannabis ; about 10 to about 80 wt % aerosol-former material;
about 15 to about 60 wt % gelling agent, the gelling agent comprising cellulose or a derivative thereof, and a non-cellulosic gelling agent; and
optionally filler, wherein the amount of gelling agent and optional filler taken together is from about 15 to about 60 wt %;
wherein the wt % values are calculated on a dry weight basis.
2 . The amorphous solid of claim 1 comprising about 1 to about 12 wt % constituent, derivative or extract of cannabis.
3 . The amorphous solid of claim 1 comprising about 15 to about 50 wt % constituent, derivative or extract of cannabis.
4 . The amorphous solid of claim 1 comprising about 15 to about 40 wt % gelling agent.
5 . The amorphous solid of claim 1 , wherein the gelling agent comprises carboxymethyl cellulose (CMC) and a non-cellulosic gelling agent.
6 . The amorphous of claim 1 , wherein the gelling agent comprises carboxymethyl cellulose (CMC) and alginate.
7 . The amorphous solid of claim 1 , wherein the weight ratio of cellulosic gelling agent to non-cellulosic gelling agent is from about 1:4 to about 4:1.
8 . The amorphous solid of claim 1 , wherein the gelling agent is not crosslinked.
9 . The amorphous solid of claim 1 , wherein the constituent, derivative or extract of cannabis is a cannabinoid.
10 . The amorphous solid of claim 9 , wherein the cannabinoid is selected from cannabigerol (CBG), cannabichromene (CBC), cannabidiol (CBD), tetrahydrocannabinol (THC), cannabinol (CBN), cannabinodiol (CBDL), cannabicyclol (CBL), cannabivarin (CBV), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabichromevarin (CBCV), cannabigerovarin (CBGV), cannabigerol monomethyl ether (CBGM), cannabinerolic acid, cannabidiolic acid (CBDA), cannabinol propyl variant (CBNV), cannabitriol (CBO), tetrahydrocannabmolic acid (THCA), and tetrahydrocannabivarinic acid (THCV A).
11 . An aerosol-generating material comprising the amorphous solid of claim 1 .
12 . A consumable for use in a non-combustible aerosol provision device, the consumable comprising the aerosol-generating material of claim 11 .
13 . A non-combustible aerosol provision system comprising the consumable of claim 12 and a non-combustible aerosol provision device.
14 . The amorphous solid of claim 1 , comprising about 20 to about 60 wt % gelling agent.
15 . The amorphous solid of claim 1 , comprising less than 20 wt % filler.
16 . The amorphous solid of claim 1 , wherein cellulosic gelling agent to non-cellulosic gelling agent is greater than 1:1.
17 . A method of forming the amorphous solid of claim 1 , the method comprising:
(a) providing a slurry comprising the constituent, derivative or extract of cannabis , the gelling agent, the gelling agent comprising cellulose or a derivative thereof, and a non-cellulosic gelling agent, the aerosol-former material or the humectant, a solvent and any optional further components of the amorphous solid;
(b) forming a layer of the slurry;
(c) optionally setting the layer of the slurry; and
(d) drying the slurry to form the amorphous solid.
18 . A composition for oral delivery of a constituent, derivative or extract of cannabis , the composition comprising an amorphous solid, the amorphous solid comprising:
about 1 to about 50 wt % constituent, derivative or extract of cannabis ; about 10 to about 80 wt % humectant;
about 15 to about 60 wt % gelling agent, the gelling agent comprising cellulose or a derivative thereof, and a non-cellulosic gelling agent; and
optionally filler, wherein the amount of gelling agent and optional filler taken together is from about 15 to about 60 wt %;
wherein the wt % values are calculated on a dry weight basis.
19 . The composition for oral delivery of claim 18 , wherein the constituent, derivative or extract of cannabis is a cannabinoid.
20 . A slurry comprising:
about 1 to about 50 wt % constituent, derivative or extract of cannabis;
about 10 to about 80 wt % aerosol-former material or humectant;
about 15 to about 60 wt % gelling agent, the gelling agent comprising cellulose or a derivative thereof, and a non-cellulosic gelling agent; and
optionally filler, wherein the amount of gelling agent and optional filler taken together is from about 15 to about 60 wt %;
wherein the wt % values are calculated on a dry weight basis; and a solvent.