US 8491938B2
· Feng
· 2013
[cited by applicant]
US 9861659B2
· Novak et al.
· 2018
[cited by applicant]
US 20060040980A1
· Lind et al.
· 2006
[cited by applicant]
US 20100172994A1
· Sigmund et al.
· 2010
[cited by applicant]
US 20110117210A1
· Ugolkov
· 2011
[cited by applicant]
US 20210187016A1
· Novak et al.
· 2021
[cited by applicant]
US 20220313731A1
· Novak et al.
· 2022
[cited by applicant]
US 20250032538A1
· Novak
· 2025
[cited by applicant]
US 20250213609A1
· Chung
· 2025
[cited by applicant]
US 20250375475A1
· Temnik et al.
· 2025
[cited by applicant]
US 20260029404A1
· Temnik et al.
· 2026
[cited by applicant]
GB 2597446A
· 2022
[cited by applicant]
KR 100925516B1
· 2009
[cited by applicant]
WO 2009072120A1
· 2009
[cited by applicant]
WO WO2021126231A1
· 2021
[cited by examiner]
WO 2022203684A1
· 2022
[cited by applicant]
Novak et al., “In Vitro Anticancer Activity of the Light Stable Zinc Isotope (64Zn) Compounds,” Anticancer Research 42, 2002, pp. 5685-5698.
[cited by applicant]
Perez Jesus et al., “Phase 1 First-in-Human Dose escalation and Dose Expansion Stud of KLS-1 (64Zinc Aspartate) in Patients With Cancer and Neurodegenerative Diseases,” Curesus, Oct. 4, 2022.
[cited by applicant]
International Search Report and Written Opinion received in PCT/US2026/018394 mailed Jun. 2, 2026, pp. 1-8.
[cited by applicant]
Schilling, Kathrin et all: “Investigations on Zinc Isotope Fractionation in Breast Cancer Tissue Using in vitro Cell Culture Uptake-Efflux Experiments” published on Jan. 20, 2022 in Frontiers in Medicine, https://www.fr…
[cited by applicant]
Schilling, Kathrin et all: “Zinc stable isotopes in urine as diagnostic for cancer of secretory organs” published on May 12, 2021: https://pubmed.ncbi.nlm.nih.gov/33877364/.
[cited by applicant]
Costello, Leslie et all: “Zinc: The Wonder Drug for the Treatment of Carcinomas” published on Jun. 25, 2020: https://pmc.ncbi.nlm.nih.gov/articles/PMC7316362/.
[cited by applicant]
Hastuti, Agustina et all: “Cu and Zn isotope ratio variations in plasma for survival prediction in hematological malignancy cases” published on Oct. 2, 2020: https://pmc.ncbi.nlm.nih.gov/articles/PMC7532200/.
[cited by applicant]
Zhang, Mengqi et all: “Isotope effect of 13C enriched testosterone on human cells” published on Feb. 16, 2022: https://www.spandidos-publications.com/10.3892/wasj.2022.144.
[cited by applicant]
Karolinska Institutet et all: “Ultralight ultrafast enzymes: Isotopes more powerful than previously thought” published on Dec. 4, 2023: https://phys.org/news/2023-12-ultralight-ultrafast-enzymes-isotopes-powerful.html.
[cited by applicant]
Guillin, Olivia et all: “Zinc Uptake by HIV-1 Viral Particles: An Isotopic Study” published on Oct. 16, 2023: https://www.mdpi.com/1422-0067/24/20/15274.
[cited by applicant]
Cheng, Yunqi et all: “Aberrance of Zinc Metalloenzymes-Induced Human Diseases and Its Potential Mechanisms” published on Dec. 13, 2021: https://pmc.ncbi.nlm.nih.gov/articles/PMC8707169/.
[cited by applicant]
Costa, Maria et all: “Zinc: From Biological Functions to Therapeutic Potential” published on Mar. 2, 2023: https://pmc.ncbi.nlm.nih.gov/articles/PMC10003636/.
[cited by applicant]
Bendellaa, Mohamed et all: “Roles of zinc in cancers: From altered metabolism to therapeutic applications” published on Aug. 23, 2023: https://onlinelibrary.wiley.com/doi/10.1002/ijc.34679.
[cited by applicant]
Wang, Jie et all: “Zinc dysregulation in cancers and its potential as a therapeutic target” published on Aug. 15, 2020: https://pmc.ncbi.nlm.nih.gov/articles/PMC7476080/.
[cited by applicant]
Narayan, Sugandha et all “Zinc dampens antitumor immunity by promoting Foxp3+ regulatory T cells” published on Aug. 24, 2024: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024. 1389387/full.
[cited by applicant]
Buj, Raquel et all: “CDKN2ALow cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance” published in Bio Rx IV on Feb. 8, 2025, https://www.biorxiv.org/content/10.1101/2025.02.0…
[cited by applicant]
Zhou, Xiao-Hong et all: “Targeting phosphatidylserine in tumor cell membranes with a zinc-containing molecule to efficiently combat tumor metastasis” published in Journal of Nanobiotechnology on May 20, 2025: https://pm…
[cited by applicant]
Khalaji, Amirreza et all: “Don't eat me/eat me signals as a novel strategy in cancer immunotherapy” published in Heliyon on Sep. 29, 2023: https://pmc.ncbi.nlm.nih.gov/articles/PMC10562801/.
[cited by applicant]
Xue, Jing et all: “Chloroquine Is a Zinc lonophore” published on Oct. 1, 2014: https://pmc.ncbi.nlm.nih.gov/articles/PMC4182877/.
[cited by applicant]
Ekinci, Ilksen Berfin et all: “Ionophore Toxicity in Animals: A Review of Clinical and Molecular Aspects” published on Jan. 15, 2023: https://pmc.ncbi.nlm.nih.gov/articles/PMC9863538/.
[cited by applicant]
Buchl, Anette et all: “Re-partitioning of Cu and Zn isotopes by modified protein expression” published on Oct. 10, 2008: https://pmc.ncbi.nlm.nih.gov/articles/PMC2570658/.
[cited by applicant]
Burián, Z et all: “Selective Inhibition of HIF1a Expression by ZnSO4 Has Antitumoral Effects in Human Melanoma” published on Apr. 26, 2020: https://pubmed.ncbi.nlm.nih.gov/30613921/.
[cited by applicant]
U.S. Appl. No. 19/076,021, filed Mar. 11, 2024.
[cited by applicant]
U.S. Appl. No. 19/068,709, filed Mar. 3, 2025.
[cited by applicant]
Paredes, Eduardo et all: “Impact of uranium uptake on isotopic fractionation and endogenous element homeostasis in human neuron-like cells” published on Nov. 21, 2018: https://pmc.ncbi.nlm.nih.gov/articles/PMC6249223/.
[cited by applicant]