Guide wire and method of manufacturing guide wire
A guide wire having a shaping property capable of shaping into a desired shape and a shape retaining property of retaining a shape at a time of shaping against an external force applied in a blood vessel, thereby allowing a procedure to be easily performed while maintaining high operability and blood vessel selectivity; and a method of manufacturing a guide wire. The guide wire includes an elongated core component including a flat portion at a distal end of the elongated core component. The flat portion is formed of a Ni—Ti alloy having an elastic portion of total indentation work of 46.0% to 59.5% and having a Martens hardness of 1300 N/mm 2 to 3000 N/mm 2 , more preferably having a Martens hardness of 1300 N/mm 2 to 2120 N/mm 2 .
1 . A guide wire, comprising:
an elongated core component including a flat portion at a distal end of the elongated core component;
the elongated core component includes, in an order from a distal end side, the flat portion, and a transition portion extending from a proximal end of the flat portion toward a proximal end side along a longitudinal direction;
the elongated core component includes a heat treatment region extending from a distal end of the flat portion to at least a part of the transition portion, the transition portion having a width and a thickness, and wherein the width of the transition portion increases toward the distal end side of the elongated core component along the longitudinal direction; and
wherein the flat portion is made of a Ni—Ti alloy having an elastic portion of total indentation work of 46.0% to 59.5% and a Martens hardness of 1300 N/mm 2 to 3000 N/mm 2 .
2 . The guide wire according to claim 1 , wherein the Martens hardness of the flat portion is 1300 N/mm 2 to 2120 N/mm 2 .
3 . The guide wire according to claim 1 , wherein a ratio of a first length from a distal end of the transition portion to a proximal end of the heat treatment region along the longitudinal direction to a second length from the distal end of the transition portion to a proximal end of the transition portion along the longitudinal direction is 10% to 100%.
4 . The guide wire according to claim 3 , wherein the ratio of the first length from the distal end of the transition portion to the proximal end of the heat treatment region along the longitudinal direction to the second length from the distal end of the transition portion to the proximal end of the transition portion along the longitudinal direction is 55% to 65%.
5 . The guide wire according to claim 1 , wherein the elongated core component includes a first core member, the first core member extending from a proximal end of the elongated core component to the distal end side of the elongated core component includes a first bonding portion, a first constant outer diameter portion, a first tapered portion, a second constant outer diameter portion, the transition portion, and the flat portion.
6 . The guide wire according to claim 5 , wherein the first bonding portion is bonded to a second bonding portion of a second core member, and an outer diameter of the first bonding portion is larger than an outer diameter of the first constant outer diameter portion and is substantially equal to an outer diameter of the second bonding portion.
7 . The guide wire according to claim 6 , wherein the outer diameter of the first bonding portion and the outer diameter of the second bonding portion are larger than an outer diameter of the first constant outer diameter portion and an outer diameter of a proximal portion of the second core member.
8 . The guide wire according to claim 1 , wherein the flat portion has a rectangular transverse sectional shape.
9 . The guide wire according to claim 8 , wherein a thickness of the flat portion is substantially constant from a distal end of the transition portion to a distal end of the flat portion.
10 . A guide wire, comprising:
an elongated core component including a flat portion at a distal end of the elongated core component, the flat portion having an elastic portion of total indentation work of 46.0% to 59.5% and a Martens hardness of 1300 N/mm 2 to 3000 N/mm 2 ;
the elongated core component includes, in an order from a distal end side, the flat portion, and a transition portion extending from a proximal end of the flat portion toward a proximal end side along a longitudinal direction;
the elongated core component includes a heat treatment region that includes an oxide film formed on an outer surface of the elongated core component extending from a distal end of the flat portion to at least a part of the transition portion along the longitudinal direction; and
a tubular body that is spirally wound around a portion of the elongated core component and covers at least a portion of the oxide film formed on the outer surface of the elongated core component.
11 . The guide wire according to claim 10 , wherein the flat portion is made of a Ni—Ti alloy.
12 . The guide wire according to claim 10 , wherein the Martens hardness of the flat portion is 1300 N/mm 2 to 2120 N/mm 2 .
13 . The guide wire according to claim 10 , wherein a ratio of a first length from a distal end of the transition portion to a proximal end of the heat treatment region along the longitudinal direction to a second length from the distal end of the transition portion to a proximal end of the transition portion along the longitudinal direction is 55% to 65%.
14 . The guide wire according to claim 10 , wherein
the elongated core component includes a first core member, the first core member extending from a proximal end of the elongated core component to the distal end side of the elongated core component includes a first bonding portion, a first constant outer diameter portion, a first tapered portion, a second constant outer diameter portion, a transition portion, and the flat portion; and
the tubular body includes a first coil and a second coil, the second coil being disposed on a proximal end side of the first coil, the first coil being disposed from the distal end of the first core member of elongated core component to an intermediate portion of the first core member of the elongated core component, and the second coil being disposed from the intermediate portion to a proximal end side of the first core member of the elongated core component.
15 . The guide wire according to claim 5 , further comprising:
a second tapered portion extending from a distal end of the second constant outer diameter to a proximal end of the transition portion, and wherein the thickness of the transition portion decreases from the second tapered portion toward the flat portion of the elongated core component along the longitudinal direction in a wedge shape.
16 . The guide wire according to claim 1 , wherein the width and the thickness of the transition portion are different.
17 . A method of manufacturing a guide wire, the method comprising:
forming the guide wire according to claim 1 , the forming of the guide wire including:
cold working the distal portion of the elongated core component such that the distal portion includes the flat portion and the transition portion extending from the proximal end of the flat portion toward the proximal end side along the longitudinal direction; and
heat treating the flat portion and the at least a part of the transition portion such that the elastic portion of total indentation work of the flat portion is 46.0% to 59.5% and the Martens hardness of the flat portion is 1300 N/mm 2 to 3000 N/mm 2 .
18 . The method according to claim 17 , wherein the Martens hardness of the flat portion is 1300 N/mm 2 to 2120 N/mm 2 .
19 . The method according to claim 17 , wherein a ratio of a first length from a distal end of the transition portion to a proximal end of the heat treatment region along the longitudinal direction to a second length from the distal end of the transition portion to a proximal end of the transition portion along the longitudinal direction is 10% to 100%.
20 . The method according to claim 19 , wherein the ratio of the first length from the distal end of the transition portion to the proximal end of the heat treatment region along the longitudinal direction to the second length from the distal end of the transition portion to the proximal end of the transition portion along the longitudinal direction is 55% to 65%.