Granted Patent B2

US 12,741,095 · App. 19/352,067 · Granted Sep 22, 2026

Inventors: Thomas Kramer (Andover, MN); Matthew H. Rust (Hudson, WI); Paul M. Goudreau (St. Paul, MN); Peter A. Hoeft (Seattle, WA); Julius C. Sund (Plymouth, MN); Peter L. Sadowski (Woodbury, MN); Michael Travanty (S. Minneapolis, MN); Patrick Madsen (Litchfield, MN)

Assignee: Antares Pharma, Inc.

A61M5/2033A61M5/20A61M5/2053A61M5/30A61M5/5086A61M2005/2013A61M2005/2026A61M2005/208A61M2005/3125A61M5/326A61M2202/0007A61M2202/048

Abstract

Claims (33)

1 . A method for delivering a medicament to a subject in need thereof, the method comprising injecting the medicament in the subject using an injector comprising:

a housing;

a trigger mechanism including:

a floating trigger member having a retaining portion; and

a ram assembly slidably mounted within the housing and having a ram defining an axis and configured to pressurize a medicament container for expelling the medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition;

an energy source associated with the ram for powering the ram to expel the medicament; and

a user-operable firing-initiation member operable for causing a rotation of the floating trigger member about the axis from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

2 . The method of claim 1 , wherein the energy source is configured to pressurize the medicament to between about 80 psi and about 1000 psi.

3 . The method of claim 1 , wherein a needle is in fluid communication with the medicament container for injecting the medicament expelled therefrom during a firing.

4 . The method of claim 3 , wherein the energy source and the needle are configured for jet injecting the medicament through the needle.

5 . The method of claim 3 , wherein the energy source and the needle are configured for injecting the medicament at a rate of between 0.2 mL/sec and about 0.75 mL/sec.

6 . The method of claim 5 , wherein the energy source and the needle are configured for injecting the medicament at a rate of about 0.2 mL/sec.

7 . The method of claim 6 , wherein the energy source and the needle are configured for injecting the medicament at a rate of about 4 mL/sec.

8 . The method of claim 3 , wherein the needle has a length of between about 4 mm and about 8 mm.

9 . The method of claim 3 , wherein the needle is a 26-28 gauge needle.

10 . The method of claim 1 , wherein about 0.2 mL to about 4 mL of medicament is delivered.

11 . The method of claim 1 , wherein the energy source is configured for powering the ram with a force of about 10 pounds to about 15 pounds.

12 . The method of claim 1 , wherein the medicament comprises an androgen.

13 . The method of claim 12 , wherein the androgen includes testosterone or a derivative or ester thereof.

14 . The method of claim 13 , wherein the androgen includes testosterone cypionate.

15 . The method of claim 14 , wherein the androgen includes testosterone enanthate.

16 . A method for delivering a medicament to a subject in need thereof, the method comprising injecting the medicament in the subject using an injector comprising:

a housing;

a trigger mechanism including:

a floating trigger member having a retaining portion; and

a ram assembly slidably mounted within the housing and having a ram defining an axis and configured to pressurize a medicament container for expelling the medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition;

an energy source associated with the ram for powering the ram to expel the medicament; and

a user-operable firing-initiation member operable for causing a rotation of the floating trigger member about the axis from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram,

wherein the energy source is configured to pressurize the medicament to between about 80 psi and about 1000 psi,

wherein the energy source and the needle are configured for injecting the medicament at a rate of between 0.2 mL/sec and about 0.75 mL/sec,

wherein about 0.2 mL to about 4 mL of medicament is delivered,

wherein the needle has a length of between about 4 mm and about 8 mm, and

wherein the energy source is configured for powering the ram with a force of about 10 pounds to about 15 pounds.

Assignments (1)

Continuity (10)

References Cited (400)