Combinations of drugs for the treatment of neoplastic disorders
The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
1. A pharmaceutical composition formulated for oral administration, said composition comprising chlorpromazine, pentamidine, and a pharmaceutically acceptable carrier, wherein said chlorpromazine and pentamidine are present in amounts that, when administered together to a patient having a neoplasm that is sensitive to the combination of said chlorpromazine and said pentamidine, reduce cell proliferation of said neoplasm.
2. The composition of claim 1 , wherein the amount of said chloropromazine is between 10 and 2500 milligrams and the amount of pentamidine is between 1 and 1000 milligrams.
3. The composition of claim 1 , wherein said pentamidine is pentamidine isethionate and said chlorpromazine is chlorpromazine hydrochloride.
4. A pharmaceutical pack comprising chlorpromazine and pentamidine.
5. The pharmaceutical pack of claim 4 , wherein the amount of said chloropromazine is between 10 and 2500 milligrams and the amount of pentamidine is between 1 and 1000 milligrams.
6. The pharmaceutical pack of claim 4 , wherein said chlorpromazine and pentamidine are formulated for administration to a patient by intravenous, intramuscular, rectal, inhalation, or oral administration.
7. The pharmaceutical pack of claim 6 , wherein said chlorpromazine and pentamidine are formulated for oral administration.
8. The pharmaceutical pack of claim 7 , wherein said pentamidine is pentamidine isethionate and said chlorpromazine is chlorpromazine hydrochloride.