Phosphonate compounds
View Patent ↗The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and the like.
1. A method for the treatment of a viral disease selected from human immunodeficiency virus, influenza, herpes simplex virus, human herpes virus, cytomegalovirus, hepatitis B and C virus, Epstein-Barr virus, varicella zoster virus, orthopox virus, ebola virus and papilloma virus comprising administering an effective amount of a compound optionally in a pharmaceutically acceptable carrier, wherein said compound is a compound having the structure (A):
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 , wherein the virus is an orthopox virus selected from variola major and minor, vaccinia, smallpox, cowpox, camelpox and monkeypox.
3. The method of claim 1 , wherein the virus is human immunodeficiency virus.
4. The method of claim 1 , wherein the virus is influenza.
5. The method of claim 1 , wherein the virus is herpes.
6. The method of claim 1 , wherein the virus is cytomegalovirus.
7. The method of claim 1 , wherein the virus is hepatitis B.
8. The method of claim 1 , wherein the virus is hepatitis C.
9. The method of claim 1 , wherein the virus is Epstein-Barr virus.
10. The method of claim 1 , wherein the virus is varicella zoster virus.
11. The method of claim 1 , wherein the virus is papilloma.