IP Library Granted Patent US 8,021,422
Granted Patent B2
US 8,021,422 · App. 12/454,440 · Granted Sep 20, 2011

Actuating mechanism for pneumatically-driven artificial heart

Assignee: Syncardia Systems, Inc.
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Quick Facts
Patent No.
US 8,021,422
App. No.
12/454,440
Granted
Sep 20, 2011
Kind
B2
Abstract

A pneumatic pump comprises two coaxial cylindrical pumping chambers, each enclosing a piston connected to the other through a partition by a tube, thereby forming a monolithic piston assembly that is driven axially by a common electrical actuator providing reciprocating motion. The volume in the bottom chamber is selected as needed to provide the desired pressure in the left ventricle of an artificial heart driven by the pump. The diameter of the tube connecting the pistons is selected such that the stroke volume of the top chamber is reduced with respect to that of the bottom chamber as needed to match the reduced pressure requirements of the right ventricle of the artificial heart. Check valves are used in each chamber to ensure venting of excess pressure during the blood ejection phase and to limit the vacuum during the fill phase.

Claims (41)

1. A pump for driving an artificial heart comprising a right ventricle and a left ventricle actuated by pneumatic pressure, comprising:

a housing;

a pair of pistons slidably mounted inside the housing;

a partition defining two separate chambers in the housing, each chamber containing one of said pistons;

a connector coupling said pair of pistons through the partition; and

a port connecting each of said chambers to a respective ventricle of the artificial heart;

wherein said separate chambers are adapted to produce respective displacements such that a maximum pressure produced by a stroke of the pump in the right ventricle is a predetermined fraction of a maximum pressure produced by said stroke in the left ventricle of the artificial heart.

2. The pump of claim 1 , wherein said separate chambers and respective pistons are substantially equal in cross-section and said connector is sized such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

3. The pump of claim 1 , wherein said separate chambers and respective pistons are substantially equal in cross-section and one of said chambers is greater in length such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

4. The pump of claim 1 , wherein said separate chambers are substantially equal in length and one of said chambers and a respective piston are greater in cross-section such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

5. The pump of claim 1 , further comprising a buffer chamber connected to one of said separate chambers such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

6. The pump of claim 1 , further comprising an actuator for producing reciprocating motion of said pistons in the separate chambers.

7. The pump of claim 1 , further comprising a pressure limiting valve and a vacuum limiting valve in each of said chambers.

8. The pump of claim 1 , wherein said housing, pistons and connector have a circular cross-section.

9. The pump of claim 8 , wherein said pistons have a diameter of approximately 3.0 inches and a stroke length of about 0.943 inches, and said connector has a diameter of 1.1 inches.

10. A pneumatically driven artificial heart comprising:

a right ventricle and a left ventricle implanted on a human heart, each comprising a diaphragm actuated by pneumatic pressure;

an exterior housing;

a pair of pistons slidably mounted inside the housing;

a partition defining two separate chambers in the housing, each chamber containing one of said pistons;

a connector coupling said pair of pistons through the partition; and

a pair of air lines connecting said chambers to respective ventricles of the artificial heart;

wherein said separate chambers are adapted to produce respective displacements such that a maximum pressure produced by a stroke of the pump in the right ventricle is a predetermined fraction of a maximum pressure produced by said stroke in the left ventricle of the artificial heart.

11. The pneumatically driven artificial heart of claim 10 , wherein said separate chambers and respective pistons are substantially equal in cross-section and said connector is sized such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

12. The pneumatically driven artificial heart of claim 10 , wherein said separate chambers and respective pistons are substantially equal in cross-section and one of said chambers is greater in length such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

13. The pneumatically driven artificial heart of claim 10 , wherein said separate chambers are substantially equal in length and one of said chambers and a respective piston are greater in cross-section such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

14. The pneumatically driven artificial heart of claim 10 , further comprising a buffer chamber connected to one of said separate chambers such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

15. The pneumatically driven artificial heart of claim 10 , wherein said air lines connecting said chambers to respective ventricles of the artificial heart are sized such that said maximum pressure produced by the stroke of the pump in the right ventricle is a predetermined fraction of the maximum pressure produced by said stroke in the left ventricle of the artificial heart.

16. The pneumatically driven artificial heart of claim 10 , further comprising an actuator for producing reciprocating motion of said pistons in the separate chambers.

17. The pneumatically driven artificial heart of claim 10 , wherein said housing, pistons and connector have a circular cross-section.

18. The pneumatically driven artificial heart of claim 17 , wherein said pistons have a diameter of approximately 3.0 inches and a stroke length of about 0.943 inches, and said connector has a diameter of 1.1 inches.

19. A pump for driving an artificial heart comprising a right ventricle and a left ventricle actuated by pneumatic pressure, comprising:

a housing of circular cross-section;

a pair of pistons slidably mounted inside the housing;

a partition defining two separate cylindrical chambers in the housing, each chamber containing one of said pistons;

a tubular connector coupling said pair of pistons through the partition;

a port connecting each of said chambers to a respective ventricle of the artificial heart;

a pressure limiting valve in each of said chambers;

a vacuum limiting valve in each of said chambers; and

an actuator for producing reciprocating motion of said pistons in the separate chambers;

wherein said pistons have a diameter of approximately 3.0 inches and a stroke length of about 0.943 inches, and said connector has a diameter of 1.1 inches, such that a maximum pressure produced by a stroke of the pump in the right ventricle is a predetermined fraction of a maximum pressure produced by said stroke in the left ventricle of the artificial heart.

Assignments (19)
RELEASE OF SECURITY INTEREST Recorded Jan 5, 2026
From: SINDEX SSI LENDING, LLC
To: SYNCARDIA SYSTEMS, LLC
Reel/Frame 073370/0158 →
SECURITY INTEREST Recorded Dec 30, 2025
From: SYNCARDIA SYSTEMS, LLC, A DELAWARE LLC
To: HIGH TRAIL SPECIAL SITUATIONS LLC
Reel/Frame 073339/0142 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 27, 2025
From: TAH WINDOWN, INC.
To: SYNCARDIA SYSTEMS, LLC
Reel/Frame 070651/0838 →
CHANGE OF NAME Recorded Mar 27, 2025
From: SYNCARDIA SYSTEMS, INC.
To: TAH WINDOWN, INC.
Reel/Frame 070668/0517 →
RELEASE OF SECURITY INTEREST Recorded Sep 19, 2016
From: SWK FUNDING LLC
To: SYNCARDIA SYSTEMS, INC.
Reel/Frame 039782/0808 →
RELEASE OF SECURITY INTEREST Recorded Sep 19, 2016
From: SWK FUNDING LLC
To: SYNCARDIA SYSTEMS, INC.
Reel/Frame 039782/0842 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2016
From: TAH WINDOWN, INC. (F/K/A SYNCARDIA SYSTEMS, INC)
To: SYNCARDIA SYSTEMS, LLC
Reel/Frame 039784/0504 →
SECURITY INTEREST Recorded Sep 19, 2016
From: SYNCARDIA SYSTEMS, LLC
To: SINDEX SSI LENDING, LLC
Reel/Frame 039784/0608 →
SECURITY INTEREST Recorded Feb 18, 2016
From: CANTOR FITZGERALD SECURITIES
To: SWK FUNDING LLC
Reel/Frame 037763/0413 →
SECURITY INTEREST Recorded Feb 18, 2016
From: CANTOR FITZGERALD SECURITIES
To: SWK FUNDING LLC
Reel/Frame 037764/0184 →
NOTICE OF GRANT OF SECURITY INTEREST Recorded Jan 22, 2016
From: SYNCARDIA SYSTEMS, INC.
To: CANTOR FITZGERALD SECURITIES
Reel/Frame 037573/0546 →
INTELLECTUAL PROPERTY SECURITY INTEREST ASSIGNMENT AGREEMENT Recorded Dec 20, 2013
From: ATHYRIUM OPPORTUNITIES FUND (A) LP, AS RESIGNING ADMINISTRATIVE AGENT
To: CANTOR FITZGERALD SECURITIES, AS SUCCESSOR ADMINISTRATIVE AGENT
Reel/Frame 031866/0599 →
SECURITY AGREEMENT Recorded Dec 16, 2013
From: SYNCARDIA SYSTEMS, INC.
To: CANTOR FITGERALD SECURITIES, AS ADMINISTRATIVE AGENT
Reel/Frame 031829/0535 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Dec 16, 2013
From: SYNCARDIA SYSTEMS, INC.
To: CANTOR FITZGERALD SECURITIES, AS ADMINISTRATIVE AGENT
Reel/Frame 031825/0369 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Mar 7, 2013
From: SILICON VALLEY BANK
To: SYNCARDIA SYSTEMS, INC.
Reel/Frame 029940/0542 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Mar 6, 2013
From: SYNCARDIA SYSTEMS, INC.
To: ATHYRIUM OPPORTUNITIES FUND (A) LP, AS ADMINISTRATIVE AGENT
Reel/Frame 029939/0433 →
AMENDED AND RESTATED IPSA Recorded Aug 6, 2012
From: SYNCARDIA SYSTEMS, INC.
To: SILICON VALLEY BANK
Reel/Frame 028734/0742 →
SECURITY AGREEMENT Recorded Sep 30, 2010
From: SYNCARDIA SYSTEMS, INC.
To: SILICON VALLEY BANK
Reel/Frame 025067/0949 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 8, 2009
From: TINKER, FRANK A.
To: SYNCARDIA SYSTEMS, INC.
Reel/Frame 022796/0928 →
Continuity (1)
Related Publication 20100292786A1 · Nov 18, 2010