Blood testing system
Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.
1. A cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, comprising:
a cartridge body comprising:
a measurement chamber;
a mixing chamber;
a testing chamber formed therein, the measurement chamber in fluid communication with the mixing chamber and the mixing chamber in fluid communication with the testing chamber through ductwork connecting the chambers; and
a valve seat configured to block flow through the ductwork when sealed; and
a cover attachable to a side of the cartridge body, the cover comprising a valve molded to the cover, the valve comprising an elastomeric material configured to distend away from an internal surface of the cover and seal with the valve seat in the cartridge body upon application of an external pressure to the valve through an external surface of the cover.
2. The cartridge device of claim 1 , wherein the valve is formed across an opening in the cover.
3. The cartridge device of claim 1 , wherein the elastomeric material is a thermoplastic elastomer.
4. The cartridge device of claim 1 , wherein the cover comprises a plurality of valves molded to the cover, the plurality of valves including the valve comprising the elastomeric material.
5. The cartridge device of claim 1 , wherein the external pressure applied to the valve is applied by a mechanical device contacting the elastomeric material of the valve.
6. The cartridge device of claim 5 , wherein the mechanical device is actuated by a solenoid.
7. The cartridge device of claim 4 , wherein a valve of the plurality of valves molded to the cover is further configured to regulate fluid flow to an overflow chamber of the cartridge body.
8. The cartridge device of claim 4 , wherein a valve of the plurality of valves molded to the cover is further configured to regulate fluid flow from a blood collection tube installed within a sample well of the cartridge body.
9. The cartridge device of claim 4 , wherein a valve of the plurality of valves molded to the cover is located between the mixing chamber and the testing chamber.