Patent Assignment
Reel/Frame 057012/0881
Notice of Termination and Release of Patent Liens and Security Interests
Recorded: 2021-07-28
Pages: 36
Assignor
NEUMEDICINES INC.
Executed: 2021-07-22
Assignee
KARYOPHARM THERAPEUTICS INC.
85 WELLS AVENUE, SUITE 210, NEWTON, MASSACHUSETTS, 02459
Covered Properties
(26)
Effective Il-12 Dosing Regimens
PCT:
PCT/US2018/066596 ↗
Cell-Based and Immune Checkpoint Inhibitor Therapies Combined with Il-12 for Treating Cancer
PCT:
PCT/US2019/012423 ↗
Uses of Il-12 in Hematopoiesis
A Method of Increasing Survival of a Human Subject Having Exposure to an Acute Exposure to Non-Therapeutic Whole Body Ionization by Administering a Therapeutically Effective Dose of Il-12
Patent:
8,921,315 →
Application:
12/430,016 →
Method for Treating Deficiency in Hematopoiesis
Method for Bone Marrow Preservation or Recovery
Uses of Il-12 in Hematopoiesis
Use of Il-12 to Increase Survival Following Acute Exposure to Ionizing Radiation
Application:
13/353,179 →
Publication:
US 2012/0189577
Uses of Il-12 in Hematopoiesis
Method for Treating Brain Cancer Using a Novel Tumor Suppressor Gene and Secreted Factor
Il-12 Formulations for Enhancing Hematopoiesis
Methods for Radiation Protection by Administering Il-12
Uses of Il-12 and the Il-12 Receptor Positive Cell in Tissue Repair and Regeneration
Mitigation of Cutaneous Injury with Il-12
Use of Il-12 to Generate Endogenous Erythropoietin
Application:
14/234,959 →
Publication:
US 2014/0178335
Method for Treating Brain Cancer Using a Novel Tumor Suppressor Gene and Secreted Factor
Il-12 for Radiation Protection and Radiation-Induced Toxicity Mitigation
Uses of Il-12 and the Il-12 Receptor Positive Cell in Tissue Repair and Regeneration
Application:
14/469,332 →
Publication:
US 2015/0110739
Use of Il-12 to Increase Survival
Application:
14/577,529 →
Publication:
US 2015/0147294
Uses of Il-12 in Hematopoiesis
Endogenous Vaccine for Cancer and Infectious Diseases
Application:
14/775,461 →
Publication:
US 2016/0045569
Il-12 Compositions and Methods of Use in Hematopoietic Recovery
Application:
14/928,439 →
Publication:
US 2016/0120948
Uses of Il-12 in Hematopoietic Immunotherapy (Hit)
Application:
14/928,499 →
Publication:
US 2016/0120949
Il-12 Formulations for Enhancing Hematopoiesis
Application:
15/881,064 →
Publication:
US 2018/0207237
Il-12 Compositions and Methods of Use in Hematopoietic Recovery
Application:
16/291,999 →
Publication:
US 2020/0030412
Use of Il-12 to Generate Endogenous Erythropoietin
Application:
16/725,896 →
Publication:
US 2020/0131240
Related Assignments
(10)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignor's Interest
Dec 27, 2018
From: BASILE, LENA A.
To: NEUMEDICINES INC.
Reel/Frame 047862/0038 →
Assignment of Assignor's Interest
Jan 29, 2019
From: BASILE, LENA A.; LAWRENCE, CHRISTOPHER E.
To: NEUMEDICINES INC.
Reel/Frame 048169/0995 →
Security Interest
Aug 8, 2019
From: NEUMEDICINES INC.
To: NITTO AVECIA PHARMA SERVICES, INC.
Reel/Frame 050004/0751 →
Security Interest
Jun 16, 2020
From: NEUMEDICINES INC.
To: FRIEDMAN, ELLIOT
Reel/Frame 052956/0270 →
Assignment of Assignor's Interest
Dec 15, 2023
From: NEUMEDICINES INC.
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 065879/0436 →
Security Interest
May 8, 2024
From: KARYOPHARM THERAPEUTICS INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB
Reel/Frame 067345/0255 →
Second Lien Patent Security Agreement
May 13, 2024
From: KARYOPHARM THERAPEUTICS INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB
Reel/Frame 067396/0532 →
Patent Security Agreement
Oct 10, 2025
From: KARYOPHARM THERAPEUTICS INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS AGENT
Reel/Frame 073058/0647 →
Patent Security Agreement
Oct 10, 2025
From: KARYOPHARM THERAPEUTICS INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL TRUSTEE
Reel/Frame 073058/0504 →
Release of Security Interest in Patents at Reel/Frame No. 67396/0532
Oct 14, 2025
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS AGENT
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 073111/0142 →