Patent Assignment
Reel/Frame 073058/0504
Patent Security Agreement
Recorded: 2025-10-10
Pages: 17
Assignor
KARYOPHARM THERAPEUTICS INC.
Executed: 2025-10-10
Assignee
WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL TRUSTEE
500 DELAWARE AVENUE, 11TH FLOOR, WILMINGTON, DELAWARE, 19801
Covered Properties
(65)
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Application:
19/075,233 →
Publication:
US US20260062391A1
Nuclear Transport Modulators and Uses Thereof
Substituted Benzofuranyl and Benzoxazolyl Compounds and Uses Thereof
Application:
19/197,345 →
Publication:
US US20260085064A1
Polymorphs of Selinexor
Application:
19/258,063 →
Publication:
US US20260152489A1
Process for Preparing XPO1 Inhibitors and Intermediates for Use in the Preparation of XPO1 Inhibitors
Crystalline Form of Selinexor
Biomarkers for Selinexor
Application:
17/598,101 →
Publication:
US US20220178927A1
Methods of Synthesis of Heteroaryl Derivatives of Triazolyl Acrylamides and Crystalline Forms
Selinexor and Analogs for Use in the Treament of Endometrial Cancer in Patients with Wild-Type TP53 Gene
Application:
19/154,281 →
Uses of Il-12 as a Replacement Immunotherapeutic
Application:
16/318,670 →
Publication:
US US20240181010A1
Il-12 Compositions and Methods of Use in Hematopoietic Recovery
Application:
17/368,346 →
Publication:
US US20220168393A1
Co-Crystal Forms of Selinexor
Nuclear Transport Modulators and Uses Thereof
Application:
18/526,900 →
Publication:
US US20240376114A1
Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators And Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Hydrazide Containing Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Substituted 2,3-Dihydrobenzofuranyl Compounds And Uses Thereof
Methods of Promoting Wound Healing Using CRM1 Inhibitors
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Substituted Benzofuranyl and Benzoxazolyl Compounds and Uses Thereof
Substituted Benzofuranyl and Benzoxazolyl Compounds and Uses Thereof
Substituted Benzofuranyl and Benzoxazolyl Compounds and Uses Thereof
Substituted Benzofuranyl and Benzoxazolyl Compounds and Uses Thereof
Multicyclic Compounds And Methods Of Using Same
Polymorphs of Selinexor
Polymorphs of Selinexor
Polymorphs of Selinexor
Polymorphs of Selinexor
Polymorphs of Selinexor
Polymorphs of Selinexor
(S,E)-3-(6-Aminopyridin-3-Yl)-N-((5-(4-(3-Fluoro-3-Methylpyrrolidine-1-Carbonyl)Phenyl)-7-(4-Fluorophenyl)Benzofuran-2-Yl)Methyl)Acrylamide for the Treatment of Cancer
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Multicyclic Compounds and Uses Thereof
The Combination of XPO1 Inhibitors and Second Agents for the Treatment of Prostate Cancer
Nuclear Transport Modulators And Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
Nuclear Transport Modulators and Uses Thereof
CRM1 Inhibitors for Treating Epilepsy
A Method of Increasing Survival of a Human Subject Having Exposure to an Acute Exposure to Non-Therapeutic Whole Body Ionization by Administering a Therapeutically Effective Dose of Il-12
Patent:
8,921,315 →
Application:
12/430,016 →
Method for Treating Brain Cancer Using a Novel Tumor Suppressor Gene and Secreted Factor
Il-12 Formulations for Enhancing Hematopoiesis
Uses of Il-12 and the Il-12 Receptor Positive Cell in Tissue Repair and Regeneration
Mitigation of Cutaneous Injury with Il-12
Methods for Radiation Protection by Administering Il-12
Il-12 for Radiation Protection and Radiation-Induced Toxicity Mitigation
Related Assignments
(17)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignor's Interest
Sep 13, 2018
From: SANDANAYAKA, VINCENT P.; SHACHAM, SHARON; MCCAULEY, DILARA; SHECHTER, SHARON
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 046870/0383 →
Notice of Security Interest in Patents
Sep 27, 2019
From: KARYOPHARM THERAPEUTICS INC.
To: HCR COLLATERAL MANAGEMENT, LLC
Reel/Frame 050575/0574 →
Assignment of Assignor's Interest
Jan 14, 2021
From: BASILE, LENA
To: NEUMEDICINES INC.
Reel/Frame 054926/0774 →
Assignment of Assignor's Interest
Jan 13, 2022
From: BASILE, LENA A.
To: NEUMEDICINES, INC.
Reel/Frame 058639/0226 →
Assignment of Assignor's Interest
Jan 14, 2022
From: NEUMEDICINES, INC.
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 058661/0931 →
Assignment of Assignor's Interest
Jun 13, 2022
From: NEUMEDICINES INC.
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 060181/0342 →
Assignment of Assignor's Interest
Nov 7, 2022
From: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
To: MACFARLAN SMITH LIMITED
Reel/Frame 061888/0166 →
Assignment of Assignor's Interest
May 19, 2023
From: HAMILTON, CLIFTON
To: JOHNSON MATTHEY PUBLIC LIMITED
Reel/Frame 063703/0155 →
Security Interest
May 8, 2024
From: KARYOPHARM THERAPEUTICS INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB
Reel/Frame 067345/0255 →
Second Lien Patent Security Agreement
May 13, 2024
From: KARYOPHARM THERAPEUTICS INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB
Reel/Frame 067396/0532 →
Assignment of Assignor's Interest
Sep 13, 2024
From: MACFARLAN SMITH LTD. D/B/A VERANOVA
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 068577/0890 →
Assignment of Assignor's Interest
Mar 18, 2025
From: AUSTAD, BRIAN C.; ROE, DAVID G.
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 070540/0244 →
Assignment of Assignor's Interest
Oct 8, 2025
From: BALOGLU, ERKAN; SHACHAM, SHARON; MCCAULEY, DILARA; KASHYAP, TRINAYAN
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 073030/0444 →
Patent Security Agreement
Oct 10, 2025
From: KARYOPHARM THERAPEUTICS INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS AGENT
Reel/Frame 073058/0647 →
Release of Security Interest in Patents at Reel/Frame No. 67396/0532
Oct 14, 2025
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS AGENT
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 073111/0142 →
Assignment of Assignor's Interest
Oct 23, 2025
From: AUSTAD, BRIAN C.; ROE, DAVID G.
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 072650/0449 →
Assignment of Assignor's Interest
Mar 31, 2026
From: BALOGLU, ERKAN; AUSTAD, BRIAN C.; ROE, DAVID G.; LEDUC, ANDREW
To: KARYOPHARM THERAPEUTICS INC.
Reel/Frame 075355/0889 →