Disposable fluid separation device and manifold assembly design with easy change-out feature
View Patent ↗Fluid separation assembly that allows easy and fast change-out even in confined spaces, and also minimizes or eliminates leakage during change-out. A fluid separation unit having a housing containing separation means, the housing having an inlet and an outlet spaced from the inlet, each including a fitting for attachment of the housing to a manifold or other device allowing fluid communication through the separation means to a point of use is provided. The fittings are designed for quick connect/disconnect, and for minimal or no leakage. The fittings may be on opposite ends, with top and bottom fittings of different configurations, thereby ensuring proper installation of the assembly. The particular medium to be separated is not particularly limited, and can include slurries, fluids including water, and pre-loaded chromatography columns.
1. A fluid separation unit and manifold assembly, said separation unit comprising a housing having an inlet, an outlet spaced from said inlet, and separation means within said housing between said inlet and said outlet;
said manifold comprising a first portion having a fluid path for fluid communication with said separation unit through said inlet, a second portion having a fluid path for fluid communication with said separation unit through said outlet;
said separation unit housing having a valve having an open position and a closed position, said valve being in said closed position and preventing the escape of fluid from said housing when said housing is disengaged from said manifold, and being in said open position and allowing fluid communication between said housing and one of said first or second portion of said manifold when said housing is engaged with said manifold;
wherein either said inlet or said outlet of said separation unit is engageable with a respective one of said first portion or said second portion of said manifold by a single pivot motion of said separation unit housing after the other of said inlet or said outlet is engaged with a respective one of said first portion or said second portion of said manifold.
2. The separation unit and manifold assembly of claim 1 , wherein said valve comprises biasing means for biasing said valve in said closed position, said valve further comprising a valve stem, and wherein said manifold comprises an actuator for actuating said valve stem against said biasing means so that said valve is in said open position.
3. The separation unit and manifold assembly of claim 1 , wherein said separation unit housing further comprises a second valve having an open position and a closed position, said second valve being in said closed position and preventing the escape of fluid from said housing when said housing is disengaged from said manifold, and being in said open position and allowing fluid communication between said housing and the other of said first and second portion of said manifold when said housing is engaged with said manifold.
4. The separation unit and manifold assembly of claim 1 , wherein one of said inlet or said outlet comprises a spherical portion, and wherein said second portion of said manifold comprises a recess for receiving said spherical portion, said recess accommodating swiveling of said spherical portion therein.
5. The separation unit and manifold assembly of claim 1 , wherein said separation unit comprises a filter.