Bidirectional blood vessel segmentation
Embodiments relate to segmenting blood vessels in angiogram images. An aspect includes a method that includes receiving and preprocessing at least one angiogram frame and preprocessing. In one embodiment, at least one angiogram frame is received and preprocessed. Bottom-up filtering of the preprocessed angiogram frame and top-down segmentation of the preprocessed angiogram frame are performed based on the results of the bottom-up filtering. The bottom-up filtering and the top-down segmentation are iteratively repeated until the difference between results of the top-down segmentation from consecutive iterations is equal to or below a threshold value. Based on determining that a difference between results of the top-down segmentation from consecutive iterations is below or equal to the threshold value, the results of the top-down segmentation are outputted.
1. A computer program product for segmenting blood vessels, the computer program product comprising a computer readable storage medium having program code embodied therewith, the program code executable by a processor to:
receive at least one angiogram frame;
preprocess the angiogram frame, wherein the preprocessing includes taking a gradient of a standard deviation of pixel intensities;
perform bottom-up filtering of the preprocessed angiogram frame;
perform top-down segmentation of the preprocessed angiogram frame based on the results of the bottom-up filtering;
iteratively repeating the bottom-up filtering and the top-down segmentation until the difference between results of the top-down segmentation from consecutive iterations is equal to or below a threshold value;
outputting the results of the top-down segmentation based on a determination that a difference between results of the top-down segmentation from consecutive iterations is below or equal to the threshold value.
2. The computer program product of claim 1 , wherein preprocessing the one or more angiogram frame comprises detecting one or more regions of interest.
3. The computer program product of claim 2 , wherein preprocessing the one or more angiogram frame comprises adaptive enhancement of the one or more regions of interest.
4. The computer program product of claim 2 , wherein preprocessing the one or more angiogram frame comprises removal of non-arterial shapes from the one or more regions of interest.
5. The computer program product of claim 1 , wherein preprocessing the one or more angiogram frame comprises applying a Butterworth bandpass filter to suppress high and low frequency background noise.
6. The computer program product of claim 1 , wherein performing bottom-up filtering comprises performing a Frangi-Radon feature filter on the one or more angiogram frame.
7. The computer program product of claim 1 , wherein the top-down segmentation model uses motion through active contours to segment blood vessels.
8. A system comprising:
a memory having computer readable computer instructions; and
a processor for executing the computer readable instructions, the instruction including:
receiving at least one angiogram frame;
preprocessing the angiogram frame, wherein the preprocessing includes taking a gradient of a standard deviation of pixel intensities;
performing bottom-up filtering of the preprocessed angiogram frame;
performing top-down segmentation of the one or more angiogram frame based on the results of the bottom-up filtering;
iteratively repeating the bottom-up filtering and the top-down segmentation until the difference between results of the top-down segmentation from consecutive iterations is equal to or below a threshold value;
outputting the results of the top-down segmentation based on a determination that a difference between results of the top-down segmentation from consecutive iterations is below or equal to the threshold value.
9. The system of claim 8 , wherein preprocessing the one or more angiogram frame comprises detecting one or more regions of interest.
10. The system of claim 9 , wherein preprocessing the one or more angiogram frame comprises adaptive enhancement of the one or more regions of interest.
11. The system of claim 9 , wherein preprocessing the one or more angiogram frame comprises removal of non-arterial shapes from the one or more regions of interest.
12. The system of claim 8 , wherein preprocessing the one or more angiogram frame comprises applying a Butterworth bandpass filter to suppress high and low frequency background noise.
13. The system of claim 8 , wherein performing bottom-up filtering comprises performing a Frangi-Radon feature filter on the one or more angiogram frame.