IP Library › Granted Patent US 10,624,946
Granted Patent B2
US 10,624,946 · App. 15/365,695 · Granted Apr 21, 2020

Treating liver diseases

Inventors: Nicholas F. LaRusso (Rochester, MN); Tetyana V. Masyuk (Rochester, MN); Melissa Muff-Luett (North Liberty, IA)
Assignee: Mayo Foundation for Medical Education and Research
A61K38/12A61K38/04A61K38/31A61K2121/00
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Quick Facts
Patent No.
US 10,624,946
App. No.
15/365,695
Granted
Apr 21, 2020
Kind
B2
Abstract

This document provides methods and materials related to treating liver conditions. For example, the methods and materials relating to the use of cAMP inhibitors to treat liver conditions are provided.

Claims (3)

1. A method for reducing kidney cyst volume in a mammal identified as having a kidney cyst, wherein said method comprises contacting said kidney cyst within said mammal with a formulation consisting of (a) a therapeutically effective amount of a somatostatin analog and (b) one or more pharmaceutically acceptable vehicles, lactic acid, mannitol, sodium bicarbonate, or a combination thereof, wherein the volume of said kidney cyst is reduced after said contacting step as compared to the volume of said kidney cyst before said contacting step.

2. The method of claim 1 , wherein said mammal is a human.

3. The method of claim 1 , wherein said somatostatin analog is octreotide, lanreotide, or vapreotide.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2017
From: LARUSSO, NICHOLAS F.; MASYUK, TETYANA V.; MUFF-LUETT, MELISSA
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 043355/0371 →
CONFIRMATORY LICENSE Recorded Jan 10, 2017
From: MAYO CLINIC ROCHESTER
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 041313/0679 →
Continuity (6)
Continuation 14924032 · Oct 27, 2015
Continuation 14665559 · Mar 23, 2015
Continuation 13533257 · Jun 26, 2012
Continuation 11915107
Provisional Application 60683617 · May 23, 2005
Related Publication 20170157205A1 · Jun 8, 2017